15 research outputs found
Correlation between Serum Zinc Level and Erythrocyte Superoxide Dismutase (SOD) Activity in Non-frail and Frail Geriatric Patients
No full textIntroduction: Frailty syndrome (FS), as a health problem in elderly, can interfere with the quality of life. Many factors play roles in its occurrence, one of which is oxidative stress. Superoxide dismutase (SOD), in which one of its components is zinc (Zn), is one of the endogenous antioxidants that plays a role in preventing oxidative stress. This study was aimed to know the correlation between serum zinc level (sZn) and erythrocyte SOD (eSOD) activity in non-frail and frail geriatric patients.Methods: This was cross-sectional study with consecutive sampling method conducted in the Geriatric Clinic Cipto Mangunkusumo hospital, from August through September 2014, on 60 patients (30 patients for each group of non-frail and frail). Data were collected from interviews, physical measurements, and venous blood sampling.Results: Among 90% of the subjects had low Zn intake, at the same time, the mean of sZn was 8.41 ± 1.36mol/l and 93.3% of the subjects had experienced Zn deficiency. The mean of eSOD activity was 1526 ± 508U/gHb, and there was no significant difference between the groups. There were no significant correlation between sZn and eSOD activity both in the overall subject (r = -0.04; p = 0.076), as well as the non-frail group (r = -0.099; p=0.604) and frail group (r = 0.01; p = 0.957).Conclusion: Serum zinc level did not have any significant correlation with the eSOD activity, neither on overall or both non-frail and frail groups.</jats:p
HIV in Geriatrics
No full textThrough both prolonged survival and late acquisition of the disease, numbers of older adults with HIV are climbing. Along with ageing process is an accumulation of HIV-associated non-AIDS related comorbidities, creating a complex patient group affected by multi-morbidity along with polypharmacy, functional decline and social issues
Determinan Diagnostik Klinis Defisiensi Vitamin D pada Wanita Berusia Lebih dari 50 Tahun
No full textPendahuluan. Prevalensi deifisiensi vitamin D pada wanita 50 tahun ke atas di Indonesia cukup tinggi namun pemeriksaan kadar vitamin D serum sangat mahal. Oleh karena itu, diperlukan alat penyaring defisiensi vitamin D yang cukup ekonomis dan sederhana untuk dikerjakan di layanan kesehatan primer.
Metode. Penelitian ini merupakan penelitian diagnostik, menggunakan desain potong lintang (cross-sectional) sehubungan dengan pengambilan data hanya dilakukan sewaktu saja. Penelitian ini dilakukan di Kotamadia Bandung selama Agustus–Oktober 2012. Pada 240 subjek, dilakukan pengumpulan data berupa karakteristik responden, diabetes mellitus, penyakit ginjal kronik, riwayat jatuh, riwayat fraktur setelah menopause, nyeri tulang, skor paparan sinar matahari, skor proteksi sinar matahari, status gizi, kinerja fisik (5 timed chair-stands dan uji sikap tandem), status kesehatan (jumlah dan derajat berat penyakit kronis), kadar vitamin D serum. Untuk pengujian statistik hubungan antara dua variabel kualitatif dikotom dilakukan dengan uji Chi-square dilanjutkan dengan uji multivariat.
Hasil. Penelitian ini menemukan hubungan yang bermakna secara statistik antara diabetes mellitus, skor proteksi matahari, kelemaan otot ekstremitas bawah dengan defiisensi vitamin D. Berdasarkan ketiga determinan tersebut, dapat dibuat sistem skoring yang dapat digunakan untuk menyaring kelompok wanita 50 tahun ke atas yang mempunyai probabilitas besar menderita defisiensi vitamin D.
Simpulan. Determinan diagnostik defisiensi vitamin D berat yang ditemukan pada penelitian ini meliputi: adanya diabetes melitus, skor proteksi matahari, kelemahan otot tungkai bawah. Sistem skoring untuk menyaring defisiensi vitamin D berat pada wanita berusia 50 tahun ke atas dapat dibuat berdasarkan ketiga determinan tersebut di atas. Bobot untuk masing-masing determinan adalah: 1 untuk diabetes mellitus dan kelemahan otot tungkai bawah serta 2 untuk skor proteksi matahari. Bila penjumlahan dari skor ketiga komponen tersebut ³2, maka subjek tersebut diprediksi menderita defisiensi vitamin D berat
Identification of Potentially Inappropriate Prescribing in Outpatient Geriatric using STOPP/START Criteria at X Hospital Jakarta
No full textChronic diseases and decreased physiological function in geriatric patients play a role in the increased
Potentially Inappropriate Prescribing (PIP) and Adverse Drug Reactions (ADR). STOPP/START Criteria
(Screening Tool of Older Person's Prescriptions/Screening Tool to Alert to Right Treatment) is one of the
screening tools to identify Potentially Inappropriate Prescribing. The purpose of this study was to find out
how much Potentially Inappropriate Medicines (PIM) potential and Potency Prescribing Omissions (PPO) at
X hospital using STOPP START toolkit. This was a non-experimental descriptive study. Samples were
collected retrospective in January-March 2017. STOPP/START criteria were used as a screening tool to
identify Potentially Inappropriate Medication (PIM) and Potential Prescribing Omissions (PPO). In 91
samples of outpatient geriatric at X hospital, the potential for PIM according to the STOPP Criteria was
1.9% of a total of 560 drugs with criteria were for the administration of benzodiazepines in patients with a
history of falls, anticholinergics and antipsychotics in dementia patients, glimepiride administration in
geriatric patients with DM type 2. For the potential of negligence in drug administration according to the
START Criteria, there was 3.8% with the most occurrence being the administration of acetylcholinesterase
inhibitors in dementia patients. Of the 560 medications administered to outpatient geriatric patients, 1.9%
were included in the STOPP criteria and 3.8% included in the START criteria
Identification of Potentially Inappropriate Prescribing in Outpatient Geriatric using STOPP/START Criteria at X Hospital Jakarta
No full textDefining the Essence of Buddhism: Appropriating the Dharma for the West
No full textThe contribution presents the examples of three prominent Western Buddhists who strongly advocated the definition of the nature of Buddhism and argued to transfer the assumed essence of Buddhism without accompanying Asian cultural baggage. The paper selected the influential Buddhist teachers Lama Govinda, highly respected author, artist and founder of the Buddhist order Arya Maitreya Mandala; the British Sangharakshita, founder of the Friends of the Western Buddhist Order, renamed to Triratna; and Stephen Batchelor, well-known meditation teacher, author and advocate of a secular Buddhism. Overall the presentation argues that the definition of an essence is equal to the subjective composition of an essence. And this procedure entails three crucial principles: that of critique, of development and of ideal. The contribution will outline these implications in the second part of the paper, followed by a brief conclusion.+ ID der Publikation: unilu_61884 + Titel der Reihe: Religious Studies in Interfaith Contexts/Religionswissenschaft in interreligiösen Kontexten + Sprache: Englisch + Bemerkungen: keinen Vertrag mit dem Verlag geschlossen, daher wohl open access publikationsfähig nach einem halben Jahr + Letzte Aktualisierung: 2023-04-20 14:56:0
Comparisons of Characteristics and Nutritional Inadequacies in Indonesian Older Adults Consuming or Refraining from Dairy Products
No full textBackground: Milk consumption in the Indonesian elderly population is among the lowest in the world, and two-thirds of the population are lactose intolerant. This might have an impact on energy and nutrient intakes. However, data on the prevalence of nutrient intake inadequacies in dairy users versus non-dairy users, as well as population characteristics, are lacking. Therefore we obtained data comparing nutritional inadequacies and characteristics of Indonesian older adults consuming or refraining from dairy products. Methods: A cross-sectional study was conducted in 2021 as a part of the INA LACTASE study, involving 194 community-dwelling older adults in the outpatient geriatric clinic at Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia. We collected data on demographic and clinical characteristics as part of a routinely performed comprehensive geriatric assessment. A structured questionnaire was developed to categorize participants as dairy-or non-dairy users based on habitual dairy intake. Food records were collected to assess nutrient intakes. The prevalence of inadequacies of energy, macronutrients, and a selection of micronutrients (calcium, vitamin D, and vitamin B12) was calculated by comparing the reported mean intakes to the recommended dietary intakes of the Indonesian population (Indonesian RDA). Prevalence ratios were calculated to measure the association between dairy product consumption and the prevalence of nutrient inadequacies. Results: We recruited 194 eligible participants. This study found that dairy users had a higher proportion of women, a higher monthly income, but a lower proportion of hypertension, diabetes mellitus, and dyslipidaemia in older adults consuming dairy products. We observed wide variability in energy and nutrient intakes, as well as a high prevalence of inadequacies for all dietary intake parameters, particularly micronutrients. Dairy users had a lower prevalence of micronutrient inadequacies than non-dairy users. The prevalence of vitamin D inadequacies in dairy users versus non-dairy users was 91.6% vs. 99.3% in men and 71.9% vs. 98.0% in women, respectively. Inadequate vitamin B12 intake was found in 60.6% of dairy users vs. 89.4% of non-dairy users in men and 65.5% vs.. 68.4% of women, respectively. The most pronounced difference was found in the prevalence of calcium intake inadequacies in dairy users vs. non-dairy users, which was 64.8% vs. 99.5% in men and 89.9% vs. 99.8% in women. We found statistically significant differences in the prevalence of calcium, vitamin D, and vitamin B inadequacies between dairy and non-dairy users. Conclusion: This study identified that dairy users had a higher monthly income and had a lower proportion of hypertension, diabetes mellitus, and dyslipidemia. In addition, we discovered a high prevalence of nutrient intakes inadequacies in Indonesian older adults, particularly among non-dairy users. Micronutrient inadequacies are major sources of concern, with statistically significant difference in calcium, vitamin D, and vitamin B12 prevalence of inadequacies
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
No full textAuthor Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)
No full textAn amendment to this paper has been published and can be accessed via a link at the top of the paper
Education Research Gender, Education and Development - A Partially Annotated and Selective Bibliography
No full textCommunity/Rural/Urban Development,
