1,200 research outputs found

    Giulia Veronica Varisco

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    The headword explains the biography and the contribution of the author Giulia Varisco to the children's literatur

    The frescoes of the Novalesa abbey complex, from restoration to preventive conservation through non-destructive diagnostics

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    The work presented shows the initial results of an interdisciplinary project focusing on actions necessary for the implementation of strategic maintenance plans to achieve preventive conservation of heritage systems. Started in May 2021, the project aims to assess and tune strategies for the prevention and mitigation of degradation phenomena affecting four historical buildings belonging to the architectonical site of the Novalesa abbey (Turin), with a particular focus on its medieval frescoes. It involves different professional actors (restorers, architects, conservation diagnostic scientists, and art historians) as well as the area's inhabitants. Based on the results of studies conducted over time on the wall paintings in the Chapel of St. Eldradus, one of the most important examples of Romanesque art in north-western Italy, the work methodology was extended to other areas of the monastery complex in need of attention. The apse of the church, the Chapels of St. Michael and the aforementioned St. Eldradus, and finally the so-called 'Camera Stellata' are now the subject of research in terms of the correlation between environmental conditions and the deterioration of the wall paintings, through the use of scientific nDT techniques and various types of analysis. The project deployed a system to collect the needed knowledge while managing the operations related to the preventive conservation plan (as i.e. salt extraction, local consolidation, etc.) and it is tended to be an asset supporting the project according to ICCROM and ICOMOS. Furthermore, the project is committed to involve the communities through dissemination initiatives. The Novalesa project was activated in the framework of PRIMA initiative funded by Fondazione Compagnia di San Paolo, having also the financial support of Città Metropolitana di Torino and Benedettini Congregation. The project operates under the supervising of the Soprintendenza Archeologia Belle Arti e Paesaggio per la Città Metropolitana di Torino

    Ytterbium Disilicate/Monosilicate Multilayer Environmental Barrier Coatings: Influence of Atmospheric Plasma Spray Parameters on Composition and Microstructure

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    first_pagesettingsOrder Article Reprints Open AccessArticle Ytterbium Disilicate/Monosilicate Multilayer Environmental Barrier Coatings: Influence of Atmospheric Plasma Spray Parameters on Composition and Microstructure by Giulia Di Iorio,Laura Paglia *ORCID,Giulia PedrizzettiORCID,Virgilio GenovaORCID,Francesco MarraORCID,Cecilia BartuliORCID andGiovanni PulciORCID INSTM Reference Laboratory for Materials and Surface Engineering, Sapienza University of Rome, Eudossiana 18, 00184 Rome, Italy * Author to whom correspondence should be addressed. Coatings 2023, 13(9), 1602; https://doi.org/10.3390/coatings13091602 Original submission received: 10 August 2023 / Revised: 31 August 2023 / Accepted: 11 September 2023 / Published: 13 September 2023 Downloadkeyboard_arrow_down Browse Figures Review Reports Versions Notes Abstract SiC/SiC ceramic matrix composites (SiCf/SiC CMCs) are regarded as the new materials for the hot-section components of aircraft gas turbine engines, since they have one-third of the density of metallic superalloys, a higher temperature capability, good mechanical strength, and excellent thermal shock resistance. However, high-temperature water-vapor-rich combustion gases can induce severe surface recession phenomena in SiC/SiC leading to component failure. For this reason, it is necessary to design protective coatings, i.e., environmental barrier coatings (EBCs), able to protect the SiC/SiC surface in combustion environments. In the present work, ytterbium monosilicate (Yb2SiO5), stable when exposed to water vapor at high temperatures, and ytterbium disilicate (Yb2Si2O7), characterized by a thermal expansion coefficient closer to that of the substrate, were selected for a multilayer EBC system. EBCs were processed using the atmospheric plasma spray (APS) technique. A set of deposition parameters were tested, varying the power of the torch, and the composition and microstructure of the deposited coatings were studied in terms of porosity, crack density, and post-deposition phase retention by performing SEM, EDS, and XRD analysis. The results allow for the definition of the influence of deposition parameters on the final properties of multilayer EBC coatings

    Multifaceted Aspects of HIV-1 Nucleocapsid Inhibition by TAR-Targeting Peptidyl-Anthraquinones Bearing Terminal Aromatic Moieties

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    2,6-dipeptidyl-anthraquinones are polycyclic planar systems substituted at opposite ring positions by short aminoacyl side chains. Derivatives with positively charged terminal amino acids showed in vitro inhibition of HIV-1 nucleocapsid (NC) protein correlating with threading intercalation through nucleic acid substrates. We found that the variation of the terminal amino acid into an aromatic moiety has profound effects on the NC inhibition of TAR–RNA melting, granting enhanced interaction with the protein. While all compounds showed appreciable NC and TAR binding, they exhibited different strengths driven by the length of the peptidyl side chains and by the stereochemistry of the terminal tyrosine. Unexpectedly, the best inhibitors of NC-induced TAR melting, characterized by the D- configuration of tyrosine, were able to form ternary complexes without competing with TAR–NC recognition sites, as shown by native mass spectrometry experiments. Furthermore, the hydrophobicity of the terminal residue enhances membrane permeation, with positive implications for further studies on these NC–TAR-targeted compounds

    Scrivere senza anestesia. La chiarezza di Giulia Niccolai

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    Il saggio colloca storicamente la narratrice e poetessa Giulia Niccolai nel canone del Novecento letterario italiano discutendone poetica e cifre stilistiche. L'ampia analisi proposta tocca tutte le opere dell'autrice evidenziandone i legami intertestuali, anche tra poesia e narrativa, e i progressivi sviluppi in un arco cronologico esteso, tra anni Sessanta e primi anni Duemila. Lo studio coglie anche l'importanza dei riferimenti alle arti visive, in particolare alla fotografia, che Giulia Niccolai ha praticato in prima persona negli anni della Neoavanguardia, e alla pittura americana.The essay places the narrator and poet Giulia Niccolai in the canonical twentieth century Italian literary discussing her poetics and stylistic figures. The wide analysis proposed touches all the works of the author highlighting the intertextual links, also between poetry and narrative, and the progressive developments in an extended chronological period, between the Sixties and early Twenties. The study also captures the importance of references to the visual arts, especially photography, which Giulia Niccolai has practiced in the years of the Neo-avant-garde, and to American painting

    Testing on mock-ups and on paintings of innovative polymeric gels for surface cleaning

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    Les recherches pour mon diplôme en Conservation et Restauration ont porté sur un nouveau type  de gels polymériques hydro-organiques pour le nettoyage des surfaces. La caractéristique principale de ces systèmes est leur haute élasticité, qui permet de les ôter des surfaces où ils sont appliqués par un mécanisme de peeling ou épluchage. L’évaluation de ces nouveaux outils a été faite à travers plusieurs tests, sur des maquettes et des cas réels. Les résultats positifs ont démontré que ils pourraient  représenter, dans le futur, une alternative valable aux systèmes de nettoyage traditionels.The research for my MA in Conservation and Restoration has focused on a new class of polymeric hydro-organo gels for cleaning surfaces. The main characteristic of these systems is their high elasticity, which allows them to be peeled from surfaces where they are applied. The assessment of these new cleaning tools has been made through several tests, on mock-ups and real cases. Positive results demonstrated that they could represent, in the future, a valid alternative to traditional cleaning systems

    BDC-Decomposition for global influence analysis

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    In biochemical networks, the steady-state input-output influence is the sign of the output steady-state variation due to a persistent positive input perturbation; if the sign does not depend on the value of the strictly positive system parameters, the influence is structural. As recently shown for small perturbations, when the linearized system approximation is valid, steady-state input-output influences can be structurally assessed, for biochemical networks with m unknown parameters, by means of a vertex algorithm with complexity 2m. This letter shows that the structural input-output influence of a biochemical network is a global property, which does not require any small-perturbation assumption. It also shows that, using a new algorithm, the complexity can be reduced down to 2m-n , where n is the system order, thus drastically reducing the computation time. Finally, when the uncertain parameters belong to known intervals, non-conservative bounds are given for the steady-state ratio between output and input, allowing for sensitivity analysis.Accepted Author ManuscriptTeam Tamas Keviczk
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