14,480 research outputs found
Estimating selection pressures on HIV-1 using phylogenetic likelihood models
No full textHuman immunodeficiency virus (HIV-1) can rapidly evolve due to selection pressures exerted by HIV-specific immune responses, antiviral agents, and to allow the virus to establish infection in different compartments in the body. Statistical models applied to HIV-1 sequence data can help to elucidate the nature of these selection pressures through comparisons of non-synonymous (or amino acid changing) and synonymous (or amino acid preserving) substitution rates. These models also need to take into account the non-independence of sequences due to their shared evolutionary history. We review how we have developed these methods and have applied them to characterize the evolution of HIV-1 in vivo. To illustrate our methods, we present an analysis of compartment-specific evolution of HIV-1 em) in blood and cerebrospinal fluid and of site-to-site variation in the gag gene of subtype C HIV-1. Copyright (C) 2008 John Wiley & Sons, Ltd
Report to Governor Neil Goldschmidt of Judge John C. Warden's corrections investigation
No full text"In accordance with Executive Order No. EO-89-12, on September 6, 1989 ..."--Page 1.Title from PDF title page (viewed on December 20, 2017).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (page ).Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Thoughts on civil liberty, [electronic resource] : on licentiousness, and faction. By the author of Essays on the characteristics, &c.
No full textAuthor of Essays on the characteristics, &c = John Brown.Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library
John Brent (1808-1882)
No full textAuthor, poet, campaigner and antiquarian John Brent was born in Rotherhithe in 1808, to a shipbuilder and his wife Susannah. The latter was from Sturry, and the family moved back to Canterbury in around 1821.
Biography for Kent Maps Online
Correspondence, C. W. Tayleure to John Brown, Jr., June 18, 1879
No full textA letter to C. W. Tayleure to John Brown, Jr. concerning the death of Brown's brother, Watson. 5 pages
The construction of Karen Karnak: The multi-author-function
No full textThis thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
The Crystal Structure of Selenourea at 20°C and ar -100°C
No full textTitle: The Crystal Structure of Selenourea at 20°C and ar -100°C, Author: John S. Rutherford, Location: ThodeThe trigonal form of selenourea has been
examined by X-ray crystallographic methods both at room temperature
and at a lower temperature ( -100°C) . The lattice parameters of
earlier workers have been refined and the space group assignment,
which requires nine crystallographically distinct SeC(NH2)2
molecules, confirmed. The crystal structure was solved using a
novel Patterson technique and differences Fourier syntheses, and
was refined by least squares using three - dimensional data obtained
0 at -100°C. Both the molecular dimensions and the crystal structure
found are compared to other members of the urea series, and the
similarity of the crystal structure to the urea- and thioureahydrocarbon
complexes discussed. Evidence is presented of N-H...Se
hydrogen bonds, supporting their recent discovery in chemically
related compounds.ThesisDoctor of Philosophy (PhD
Thoughts on civil liberty: on licentiousness, and faction. By the author of Essays on the characteristics, &c.
No full text167,[1]p. ; 8⁰.Author of Essays on the characteristics, &c = John Brown.Reproduction of original from the British Library.English Short Title Catalog, ESTCT789.Electronic data. Farmington Hills, Mich. : Thomson Gale, 2003. Page image (PNG). Digitized image of the microfilm version produced in Woodbridge, CT by Research Publications, 1982-2002 (later known as Primary Source Microfilm, an imprint of the Gale Group)
John Satterfield behind podium.
No full textSatterfield, John C.; American Bar Associationhttps://egrove.olemiss.edu/satterfield/1000/thumbnail.jp
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