101,001 research outputs found
Metabolomics dataset of 44 Propionibacterium freudenreichii for Scoary2
No full text44 yogurts were produced, each by combining a different (sequenced) Propionibacterium freudenreichii strain with the same starter culture (Yoflex® YC-381). The metabolomes of these yogurts were measured using liquid chromatography MS (LC-MS) and gas chromatography MS (GC-MS), the latter measuring the yogurt’s volatile metabolites (volatiles). The aim of this study was to investigate the effect of the pan-genome of the added bacterial strains on the phenotype of the yogurts. We discovered two genes affecting carnitine metabolism.This data was analyzed using Scoary2: https://github.com/MrTomRod/scoary-2/wiki/Output#example-outputFile descriptions:- traits_44_noraw.tsv: corrected and filtered metabolomics data. Includes lc-ms as well as gc-ms volatiles data- traits_info_44_noraw.tsv: metadata about the measured metabolites, e.g. m/z, retention times, descriptions, putative HMDB IDs, etc.- isolate_info_44.tsv: links each sample to its species, in this case, all samples are Propionibacterium freudenreichii.- N0.tsv: a list of Hierarchical Orthogroups (HOGs) that groups orthologous genes together. It was created using OrthoFinder v2.5.4 based on protein FASTA files.- N0_best_names.tsv: maps each HOG to a putative descriptio
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Natural hazards knowledge and risk perception of Wujie indigenous community in Taiwan
No full textThe purpose of this work was to investigate the natural hazards knowledge and risk perception of Wujie indigenous community, located in Fazhi village in the Central Mountain Range of Taiwan. Natural hazards (e.g. floods, landslides and debris flows) are one of the most critical issues for the Taiwanese government and for the people living in mountainous areas. During the last centuries, the native people experienced economic competition and military conflicts with a series of colonial periods that have led to a progressive loss of their original cultural identity. The motivation of selecting the case study of Wujie community is because (1) it has experienced, more than others, generations of devastating colonial oppression by foreign governments; (2) several landslides and debris flows occurred during the last decades; and (3) the area was subject of land exploitation and several hydroelectric projects. Two questions appear spontaneously: How are those indigenous people nowadays living with natural hazards? Have land use change and the anthropic pressure affected their knowledge and perception of natural hazards and related risk? This research, one of the first carried out in Taiwan involving an indigenous community, can offer a unique opportunity to answer these questions. The investigation utilized a variety of participatory methods by the use of face-to-face interviews. Results revealed that residents felt a high worry about landslide and flood risks. However they felt a slight preparedness to face them. The most considerable differences were found between the personal evaluations respect to the overall community. The discrepancy in the attitude–behavioural link may derive from an unsatisfactory level of communication and information probably ground in the absence of community participation in the decision-making process. Results revealed also the complexity of residents’ perspectives about the causes of the increase of natural hazards occurrence. To this point, the community has ascribed this phenomenon to several uncontrolled human actions during colonial period that have affected the environment and their living. In addition, gender, age education and experience of natural hazards were found to be significant predictors in this study. Paying attention to the indigenous perception of a hazard and risk can increase the effectiveness of projects implemented by practitioners who might need to communicate risks in the future. It also helps governments in their possible need to order evacuations, and future researchers to conduct similar projects
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Measuring industry-science links through inventor-author relations: A profiling method
No full textIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
Proposal of forest road re-engineering in the area of state forest in Jezersko (Slovenia)
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