1,720,968 research outputs found
STUDY OF ORAL CAVITY LESIONS BY INFRARED SPECTROSCOPY
No full textFourier transform infrared (FTIR) microspectroscopy is considered a useful tool in the biomedical field, for analysing in situ and at cellular level, very small areas of tissues and cells, with minimal sample preparation and without the use of stains or probes. This spectroscopic technique has been successfully applied to analyse biological samples from patients affected by tumoral pathologies, with particular attention to oral cavity lesions. In this study, we describe the application of FTIR microspectroscopy to characterize and discriminate the most recurrent benign and malignant diseases of oral cavity compartment. Infrared maps were acquired on tissues affected by the following pathologies: squamous cell carcinoma, adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, squamous dysplasia, keratocystic odontogenic tumor, radicular cyst, residual cyst, unicystic ameloblastoma, and ameloblastic fibroma, together with healthy tissue samples (used as control group). The epithelial and connective components of all samples were distinguished and submitted to multivariate analysis. The results were in agreement with histological suggestions
VIBRATIONAL MAPPING OF SINONASAL LESIONS BY FOURIER TRANSFORM INFRARED IMAGING SPECTROSCOPY
No full textFourier transform infrared imaging (FTIRI) is a powerful tool for analyzing biochemical changes in
tumoral tissues. The head and neck region is characterized by a great variety of lesions, with different degrees
of malignancy, which are often difficult to diagnose. Schneiderian papillomas are sinonasal benign neoplasms
arising from the Schneiderian mucosa; they can evolve into malignant tumoral lesions (squamous cell carcinoma).
In addition, they can sometimes be confused with the more common inflammatory polyps. Therefore,
an early and definitive diagnosis of this pathology is mandatory. Progressing in our research on the study of oral
cavity lesions, 15 sections consisting of inflammatory sinonasal polyps, benign Schneiderian papillomas, and
sinonasal undifferentiated carcinomas were analyzed using FTIRI. To allow a rigorous description of these pathologies
and to gain objective diagnosis, the epithelial layer and the adjacent connective tissue of each section
were separately investigated by following a multivariate analysis approach. According to the nature of the lesion,
interesting modifications were detected in the average spectra of the different tissue components, above all in
the lipid and protein patterns. Specific band-area ratios acting as spectral markers of the different pathologies
were also highlighted. © 2015 Society of Photo-Optical Instrumentation Engineers (SPIE) [DOI: 10.1117/1.JBO.20.12.125003
Periodontal status in the Down’s syndrome subjects living in central-eastern Italy: the effects of place of living
No full textAim: The purpose of this study was to determine the influence of the place of living on periodontal status of 62 Down’s syndrome (DS) subjects resident at home (DSH) or in specialized institutes (DSI) in central-eastern Italy. Methods: The demographic characteristics of the subjects and the periodontal variables were evaluated according to their living conditions. Descriptive analyses were conducted by stratifying subjects into three age groups (0-13; 14-22; >23 years), using medians and 25th - 75th percentiles to summarized data. Comparisons between DSH and DSI subjects were performed using Wilcoxon rank sum test. The effect of demographic and clinical variables on periodontal status was evaluated by means of quantile regression analysis. Results: No significant differences resulted between DSH and DSI patients, when compared for gender, age and mental retardation. No significant differences were found in the periodontal variables for the subjects with 0-13 years, while DSI subjects between 14-22 years of age presented higher levels of Plaque Index, Probing Depth, Clinical Attachment Loss and a lower number of surviving teeth compared to DSH subjects. When DSI and DSH groups ≥23 years of age were compared no differences were observed in the periodontal conditions except for PI and the number of surviving teeth. Age, body mass index, and severe mental retardation were found to be significant predictors of periodontal conditions. Conclusions: Institutionalization has a negative effect on surviving teeth number of Down’s syndrome subjects. Furthermore, the home care seems to produce benefits on the periodontal conditions of DSH 14-22 years of age
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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