1,106 research outputs found
Supplemental Material, Appendix_A_(1) - Personality (at Intrapsychic and Interpersonal Level) Associated With Quality of Life in Patients With Cancer (Lung and Colon)
No full textSupplemental Material, Appendix_A_(1) for Personality (at Intrapsychic and Interpersonal Level) Associated With Quality of Life in Patients With Cancer (Lung and Colon) by Maria Velia Giulietti, Anna Vespa, Marica Ottaviani, Rossana Berardi, Giancarlo Balercia, Giorgio Arnaldi, Pisana Gattafoni, Paolo Fabbietti, Mirko Di Rosa and Roberta Spatuzzi in Cancer Control</p
Desmopressin test in the differential diagnosis of Pseudo-Cushing state from Cushing’s disease.
No full textContext: The desmopressin (DDAVP) test has been proposed to discriminate Cushing's disease (CD) from pseudo-Cushing states (PC); however, current information on its value is scarce and contradictory.
Objective: The aim of the study was to assess the ability of the DDAVP test in distinguishing between these conditions, with emphasis on subjects with mild hypercortisolism.
Design and setting: We conducted a retrospective/prospective study at the Division of Endocrinology, Polytechnic University of Marche, Ancona, Italy.
Patients: The study included 52 subjects with CD, 28 with PC, and 31 control subjects (CT).
Intervention(s): We performed the DDAVP test and standard diagnostic procedures for the diagnosis of Cushing's syndrome.
Main outcome measure(s): The diagnosis/exclusion of CD was measured.
Results: Interpretation of the DDAVP test based on percentage and absolute increment of cortisol and ACTH did not afford acceptable values of both sensitivity (SE) and specificity (SP). CD diagnosis based on simultaneous positivity for basal serum cortisol greater than 331 nmol/liter and absolute ACTH increment greater than 4 pmol/liter and its exclusion in subjects negative for one or both measures yielded an SE of 90.3% and an SP of 91.5%. The approach was also highly effective in distinguishing PC from: 1) CD with moderate values of urinary free cortisol (SE, 86.9%; SP, 92.8%); 2) CD with moderate values of serum cortisol after dexamethasone suppression (SE, 86.6%; SP, 92.8%); and 3) CD with moderate values of midnight serum cortisol (SE, 100%; SP, 92.8%).
Conclusions: Interpretation of the DDAVP test through a combination of parameters allowed effective discrimination of CD from PC, even in subjects with mild hypercortisolism
Measurement of jet spectra in Pb-Pb collisions at √sNN=2.76 TeV with the ALICE detector at the LHC
No full textWe report a measurement of transverse momentum spectra of jets detected with the ALICE detector in Pb-Pb collisions at √sNN=2.76 TeV. Jets are reconstructed from charged particles using the anti-kT jet algorithm. The background from soft particle production is determined for each event and subtracted. The remaining influence of underlying event fluctuations is quantified by embedding different probes into heavy-ion data. The reconstructed transverse momentum spectrum is corrected for background fluctuations by unfolding. We compare the inclusive jet spectra reconstructed with R = 0.2 and R = 0.3 for different centrality classes and compare the jet yield in Pb–Pb and pp events
p/π Ratio in Di-Hadron Correlations
No full textParticle ratios are important observables used to constrain models of particle production in heavy-ion collisions. In this work we report on a measurement of the p/pi ratio in the transverse momentum range 2.0 < p_{T,assoc} < 4.0 GeV/c, associated with a charged trigger particle of 5.0 < p_{T,trig} < 10.0 GeV/c, in 0-10% central Pb--Pb collisions at sqrt{s_{NN}}=2.76 TeV. The ratio is measured in the jet peak and in a region at large Delta eta separation from the peak (bulk region). The presented results are based on 14M minimum-bias Pb--Pb collisions, recorded by the ALICE detector. It is observed that the p/pi ratio in the bulk region is compatible with the p/pi ratio of an inclusive measurement, and is much larger than the p/pi ratio in the jet peak. The p/pi ratio in the jet peak is compatible with a PYTHIA reference, in which fragmentation in the vacuum is the dominant mechanism of particle production.Particle ratios are important observables used to constrain models of particle production in heavy-ion collisions. In this work we report on a measurement of the p/π ratio in the transverse momentum range 2.0<pT,assoc<4.0GeV/c , associated with a charged trigger particle of 5.0<pT,trig<10.0GeV/c , in 0–10% central Pb–Pb collisions at sNN=2.76TeV . The ratio is measured in the jet peak and in a region at large Δ η separation from the peak (bulk region). The presented results are based on 14M minimum-bias Pb–Pb collisions, recorded by the ALICE detector. It is observed that the p/π ratio in the bulk region is compatible with the p/π ratio of an inclusive measurement, and is much larger than the p/π ratio in the jet peak. The p/π ratio in the jet peak is compatible with a PYTHIA reference, in which fragmentation in the vacuum is the dominant mechanism of particle production.Particle ratios are important observables used to constrain models of particle production in heavy-ion collisions. In this work we report on a measurement of the p/pi ratio in the transverse momentum range 2.0 < p_{T,assoc} < 4.0 GeV/c, associated with a charged trigger particle of 5.0 < p_{T,trig} < 10.0 GeV/c, in 0-10% central Pb--Pb collisions at sqrt{s_{NN}}=2.76 TeV. The ratio is measured in the jet peak and in a region at large Delta eta separation from the peak (bulk region). The presented results are based on 14M minimum-bias Pb--Pb collisions, recorded by the ALICE detector. It is observed that the p/pi ratio in the bulk region is compatible with the p/pi ratio of an inclusive measurement, and is much larger than the p/pi ratio in the jet peak. The p/pi ratio in the jet peak is compatible with a PYTHIA reference, in which fragmentation in the vacuum is the dominant mechanism of particle production
Overview of recent ALICE results
No full textALICE is the LHC experiment devoted to the study of heavy-ion collisions. While results from Pb-Pb collisions at s**(1/2)_NN = 2.76 TeV provide insight on the properties of the plasma of quarks and gluons, formed in nucleus-nucleus interactions, the study of p-Pb collisions at s**(1/2)_NN = 5.02 TeV allows a deeper understanding of cold nuclear matter effects. Therefore, p-Pb results turn out to be a powerful tool to provide a baseline for Pb-Pb, to correctly quantify how the various observables are affected by genuine hot medium effects. In this proceeding, a selection of the most recent ALICE results on the medium global properties and on heavy-flavour and quarkonium production will be discussed
Quarkonium production in heavy-ion collisions
No full textThe production of quarkonium states plays a crucial role among the probes to investigate the formation of the plasma of quarks and gluons (QGP) in heavy-ion collisions. A review of the charmonium and bottomonium production, mainly focussing on the latest results from the LHC experiments, is presented
Charm resonance production in heavy-ion collisions
No full textThe production of charmonium states plays an important role among the probes to investigate the formation of a plasma of quarks and gluons (QGP) in heavy-ion collisions. A review of the main J/ψ and ψ(2S) results is presented, focussing on the most recent achievements from the LHC experiments
Rage and aggressive behaviour in frontal lobe epilepsy: description of a case and review of the mechanisms of aggressive behaviour in epilepsy and dementia
No full textThe study of dementia and epilepsy may provide particular insight into behavioural alterations. We describe a rare case of ictal aggressive behaviour in a patient with focal epilepsy associated with a non-dominant dorso-lateral prefrontal lesion. During focal seizures, our patient showed intense agitation and anger, for a long time misinterpreted as psychogenic attacks, which disappeared after epilepsy surgery. The defined anatomical origin of such ictal emotional behaviour is not fully understood, however, the dorso-lateral prefrontal area appears to correlate less frequently with aggressiveness compared to the antero-mesial area. We describe the electroclinical data of our patient and provide a brief review of the mechanisms underlying aggressive conduct in epilepsy and dementia. An understanding of this mechanism could help to clarify the neural basis and treatment of violence associated with these and other neurological disorders
Using temperament and character dimensions (TCI) to analyze the personality profiles of adults and older adults with cancer managed in outpatient settings
Get PDFIntroduction This study aimed to investigate profiles of personality evaluated by temperament and character dimensions (TCI) in 638 adult and older adult patients (CP) who had recently been diagnosed with breast, colon, lung, and other kinds of cancer (female and male subjects were assessed). Tests: Temperament and Character Inventory (TCI). Statistical analysis: cluster K-means analysis for personality traits. Results Two different personality profiles emerged: "Low self-determination and pessimism" (Profile 1) and "Self-determination and self-caring (medium)" (Profile 2). The following significant differences were observed in the TCI dimensions between the two profiles: Temperament-Novelty-Seeking (NS) (p < 0.001); Harm-Avoidance (HA) (p < 0.001); Reward-Dependence (RD) (p < 0.001); Persistence (PS) (p < 0.001); Character-Self-Directness (SD) (p < 0.001); Cooperativeness (C) (p > 0.001); Self-Transcendence (ST) (p < 0.001). No differences in the two profiles were found between adult and elderly patients. Profile 1 - "Low self-determination and pessimism": Patients with this profile present low resistance to frustration, poor search for novelty and solutions (NS), anxiety and pessimism (medium HA), high social attachment and dependence on the approval of others (medium-high RD), and low self-determination (PS) as temperament dimensions; and medium-low self-direction, low autonomy and ability to adapt (SD-medium-low), medium cooperativeness (C), and low self-transcendence (ST) as character dimensions. Profile 2 - "Self-determination and self-caring (medium)": Patients with this profile have resistance to frustration, ability to search for novelty and solutions (medium-NS), low anxiety and pessimism (HA), low social attachment and dependence on approval (medium-low-RD), and determination (medium-high PS) as dimensions of temperament; and autonomy and capacity for adaptation and self-direction (SD), capacity for cooperation (high-CO), and self-transcendence (medium-high-ST) as character dimensions. Conclusion Personality screening allows a better understanding of the difficulties of the individual patient and the planning of targeted psychotherapeutic interventions that promote quality of life and good adaptation to the disease course
Psychometric properties of the Italian version of the Revised Temperament and Character Inventory (TCI-140) in adults and older adults with cancer managed in outpatient settings
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