1,678 research outputs found
Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba
No full textArchaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly to dsDNA (double-stranded DNA) than to either ssDNA (single-stranded DNA) or RNA. The Alba protein is dimeric in solution, and forms distinct ordered complexes with DNA that have been visualized by electron microscopy studies; these studies suggest that, on binding dsDNA, the protein forms extended helical protein fibres. An end-to-end association of consecutive Alba dimers is suggested by the presence of a dimer-dimer interface in crystal structures of Alba from several species, and by the strong conservation of the interface residues, centred on Are and Phe(60). In the present study we map perturbation of the polypeptide backbone of Alba upon binding to DNA and RNA by NMR, and demonstrate the central role of Phe(60) in forming the dimer dimer interface. Site-directed spin labelling and pulsed ESR are used to confirm that an end-to-end, dimer dimer interaction forms in the presence of dsDNA.Peer reviewe
First person – Alba Delrio-Lorenzo
No full textFirst Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Alba Delrio-Lorenzo is first author on ‘Sarcoplasmic reticulum Ca2+ decreases with age and correlates with the decline in muscle function in Drosophila’, published in JCS. Alba is a PhD student in the lab of Javier García-Sancho and María Teresa Alonso at the Instituto de Biología y Genética Molecular (IBGM), University of Valladolid, Spain, investigating the molecular mechanisms implicated in aging, particularly muscle aging.Peer reviewe
Reniera alba var. pontica Czerniavsky 1880
No full text<i>Reniera alba</i> var. <i>pontica</i> f. <i>polypoides</i> Czerniavsky, 1880 <p> <i>Reniera alba</i> var. <i>pontica</i> f. <i>polypoides</i> Czerniavsky, 1880: 116. (no illustration).</p> <p>Described by Czerniavsky from the Crimea region, Yalta bay, approximate coordinates 44.48°N 34.17°E, and Hursuf Bay, approximate coordinates 44.84°N 34.28°E. The combination is invalid on account of having four names (ICZN art. 45.5).</p> <p> I propose to assign the specimen to the subspecies <i>H. alba</i> subsp. <i>albapontica</i> <b>nom.nov</b> <b>.</b></p>Published as part of <i>Van Soest, Rob W. M., 2024, Correcting sponge names: nomenclatural update of lower taxa level Porifera, pp. 1-122 in Zootaxa 5398 (1)</i> on page 43, DOI: 10.11646/zootaxa.5398.1.1, <a href="http://zenodo.org/record/10494167">http://zenodo.org/record/10494167</a>
Reniera alba var. pontica Czerniavsky 1880
No full text<i>Reniera alba</i> var. <i>pontica</i> Czerniavsky, 1880 <p> <i>Reniera alba</i> var. <i>pontica</i> Czerniavsky, 1880: 116 (no illustration).</p> <p> <i>Reniera albapontica</i> Van Soest, 2001: 98 (listed only, erroneously assigned to Czerniavsky, making it a <i>nomen nudum</i>); Ereskovsky <i>et al.</i> 2016: table A1 (listed only); Ereskovsky <i>et al</i>. 2018: table 3, listed only.</p> <p> <i>Reniera alba</i> var. <i>pontica</i> (Czerniavsky, 1880) is here treated as a Black Sea subspecies of <i>Haliclona alba</i> (Schmidt, 1862) described from the Adriatic, assuming the Black Sea has endemic forms of Mediterranean species. Still, Ereskovsky <i>et al.</i> (2016, 2018) list also <i>Haliclona alba</i> s.s. from the Black Sea, but there are no descriptions in the Ereskovsky <i>et al.</i> papers. Since Schmidt’s species lacks recent records or descriptions the status of the present variety is <i>taxon inquirendum</i>.</p> <p> This is a secondary homonym of <i>Haliclona pontica</i> (Czerniavsky, 1880: 231 as <i>Cacochalina digitata</i> var. <i>pontica</i>). Because the combination <i>Haliclona pontica</i> was already used for this taxon by Ereskovsky <i>et al.</i> (2016: 405, table A1), <i>Cacochalina digitata</i> var. <i>pontica</i> became the senior homonym, despite <i>Reniera alba</i> var. <i>pontica</i> having page priority (cf. above). The two <i>pontica</i> ’s are currently considered congeneric, so the present combination needs a new subspecies name (ICZN art. 59.1), for which I propose above <i>H. alba</i> subsp. <i>albapontica</i> <b>nom.nov.</b>, making use of an unfortunate misspelling of the original homonym in Van Soest (2001). That name is here treated as an unavailable <i>nomen nudum</i>, which is now made available with the present authorship and year (Ereskovsky <i>et al.</i> 2016: table A1 only lists the name as the earlier <i>nomen nudum</i> of Van Soest, 2001, and no indication is given by tese authors that it concerns a <i>nomen novum</i> or <i>nova species</i>).</p>Published as part of <i>Van Soest, Rob W. M., 2024, Correcting sponge names: nomenclatural update of lower taxa level Porifera, pp. 1-122 in Zootaxa 5398 (1)</i> on page 43, DOI: 10.11646/zootaxa.5398.1.1, <a href="http://zenodo.org/record/10494167">http://zenodo.org/record/10494167</a>
The Author/Translator Interactional Process. A Case Study
No full textSee Naples and Kill (1988) is a lively and colourful novel by the con-temporary English writer, Gregory Dowling, translated into Italian in 2015.
Following the tradition of translation studies (Venuti 2000, Bass-nett 2002, Cronin 2006), this paper analyses the rewriting process of literary translation, considering in particular the fruitful but sometimes tense and even conflictual relationship between writer and translator.
The translation of the novel See Naples and Kill was an ongoing rewriting process entailing a constant dialogue between the writer and the translator. Therefore, the study aims at answering two main ques-tions: what happens if the rewriting process of translation is constant-ly questioned by the author? What happens if the author has a good mastery of the target language and s/he is her/himself a translator?
By exploring the relationship between translation and re-creation, the research focuses on the differences and similarities between the primary creation (source text) and the secondary creation (target text), and aims to verify in which way the dialogic encounter of two different personalities and cultures does not make them merge but, by retaining their own uniqueness, leads eventually to their mutually en-riching each other. A comparative analysis of the source text and the different drafts of the translated version accompanied by the author’s comments will shed light on the tense author-translator relationship in the specific case under investigation and how both actors handle this tension in order to create a new work resulting from the (dis)agreement of the two parties
Niphates alba
No full text<i>Niphates alba</i> van Soest, 1980 <p> Synonymy and references. <i>Niphates alba</i> van Soest, 1980: 40, fig. 14, pls. 6: 4, 7: 1. <i>Protophlitaspongia antillana</i> Pulitzer- Finali, 1986:138, figs. 59, 60.</p> <p> <b>Material.</b> USNM 1229114, Curlew Bank forereef cave, 20 m; C. Piantoni, col. 28 Jun 2007.</p> <p> <b>External morphology.</b> An erect, cylindrical branch emerging from a small cushion, 12 cm long, 15–23 mm in diameter. Two obvious oscula, flush with the surface, 2–4 mm diameter, numerous smaller pores of undetermined function. Rough surface, stiff elastic consistency. Color light gray, with tan to orange tinge in the crustose part.</p> <p> <b>Skeleton structure.</b> The ectosomal skeleton is a meshwork of 20–60 µm thick fibers cored by spicules. In the choanosome, the skeleton is formed by robust, ascending, interconnected fibers cored and accompanied by spicules. Primary fibers up to 100 µm in diameter, secondary fibers 30–80 µm.</p> <p> <b>Spicules.</b> Isodiametric oxeas with abrupt, dull points, approaching strongylote forms; a few are styloid: 150–180 x 6–9 (<i>164 x 8</i>) Μm.</p> <p> <b>Ecology.</b> The only specimen encountered was found in a forereef cave, in 20 m; elsewhere reported from reefs in 20– 40 m.</p> <p> <b>Distribution.</b> Gulf of Mexico and Caribbean.</p>Published as part of <i>Rützler, Klaus, Piantoni, Carla, Van, Rob W. M. & Díaz, Cristina, 2014, Diversity of sponges (Porifera) from cryptic habitats on the Belize barrier reef near Carrie Bow Cay, pp. 1-129 in Zootaxa 3805 (1)</i> on page 84, DOI: 10.11646/zootaxa.3805.1.1, <a href="http://zenodo.org/record/249983">http://zenodo.org/record/249983</a>
Risk factors of typhoid infection in the Indonesian archipelago
No full text<p>Datasets and accompanying questionnaires for the epidemiological study on risk factors for typhoid infection conducted between June 2010 and June 2011 from 14 selected hospitals and health centres in three Indonesian islands: in and around Makassar in South Sulawesi (Sulawesi); Jayapura (Papua); Samarinda in East-Kalimantan (Kalimantan).</p>
<p>The mansucript describing methods and results has been accepted for publication in PLOS ONE "Risk factors of typhoid infection in the Indonesian archipelago" by Sandra Alba, Mirjam I Bakker, Mochammad Hatta, Pauline FD Scheelbeek, Ressy Dwiyanti<sup> </sup>, Romi Usman, Andi R Sultan, Muhammad Sabir, Nataniel Tandirogan, Masyhudi Amir, Yadi Yasir, Rob Pastoor, Stella van Beers,Henk L Smits</p>
A ALBA e a luta pela hegemonia no continente americano: uma topologia do discurso bolivariano
Get PDFDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-graduação em Sociologia PolíticaO objetivo da dissertação é analisar o movimento bolivariano, liderado pela Venezuela, enquanto projeto de construção de uma nova hegemonia na América Latina e o Caribe. Tal projeto se constrói discursivamente em oposição à histórica hegemonia pan-americana liderada pelos Estados Unidos (EUA). Para isso é estudada a ALBA (Aliança Bolivariana para os Povos de nossa América) como organização internacional que facilita a alineação de países e sociedades latino-americanos em relação ao movimento bolivariano, gerando novas modalidades de construção de sentido, assim como novas vias e regras de relacionamento internacional. A pesquisa analisa os discursos de mandatários nas reuniões de Cúpula da ALBA, e, apelando à teoria do discurso de Ernesto Laclau, identifica nesse conjunto os três passos previstos pelo autor na configuração de um desafio hegemônico: (1) o estabelecimento de um antagonismo face ao imperialismo dos EUA que é identificado como o poder hegemônico institucionalizado, e a dicotomização do espaço social americano através da construção de uma fronteira entre esse poder e o resto da comunidade (América Latina e o Caribe); (2) a articulação contingente entre diversas demandas sociais, características da América Latina e do Caribe, cuja insatisfação é atribuída ao imperialismo dos EUA; e (3) a formação de um campo popular, através da expressão positiva dessas demandas numa nova identidade, no caso a identidade bolivariana. A pesquisa conclui que o movimento bolivariano consegue gerar elementos para permitir uma nova lógica de construção de sentido, configurando assim estruturalmente um campo de luta pela hegemonia. Porém, também são destacados vários problemas nessa tarefa, especialmente ligados à identificação de diversas unidades com o bolivarianismo.The dissertation research the Bolivarian Movement, headed by Venezuela, as a new hegemonic project, still under construction, at Latin America and the Caribbean. This hegemonic project is discursively constructed in opposition to the historic Pan American hegemony, led by the U.S. In this way, the Bolivarian Alliance for the Peoples of Our America (ALBA) is approached as an international organization that seeks to align the Latin American countries and societies behind the Bolivarian Movment. The ALBA generates new ways of sense-making, as well as new norms of international relations. The research analyzes the speeches at the ALBA's presidential summits, using the Ernesto Laclau's Discourse Theory, and identifying the three steps proposed by this author to the hegemonic construction: Firstly, the establishment of an antagonism against U.S. imperialism and the dicotomization of the hemispheric social space, through the definition of a boundary between the powerful country and the rest of continental community (Latina America and the Caribe). Secondly, the contingent articulation of a variety of social demands, which dissatisfaction are ascribed to the U.S. imperialism. Thirdly, the formation of a new popular field, through the positive expression on a new identity of this unified set of demands, in this case the Bolivarian identity. The dissertation concludes that the Bolivarian movement manages a new logic of sense-making, and therefore places the hegemonic struggle in a new structural field. However, it also identified some problems on this task, particularly in the difficulty to construct a Bolivarian identity shared by various social unities (countries, societies and social sectors)
Venezuela tra Alba e Mercosur. Un ruolo ambivalente
Get PDFGiacomo Pellini, "Venezuela tra Alba e Mercosur", in: Visioni LatinoAmericane, 11 (2014), pp.48-62L’autore esamina l’attivismo di Hugo Châvez nei processi di integrazione latinoamericana soffermandosi in particolare sull’Alba e il Mercosur. Mette a confronto, da una parte, la leadership esercitata dal Venezuela all’interno dell’Alba e dall’altra il ruolo di secondo piano del Venezuela all’interno del Mercosur. Evidenzia come per il Paese sia più vantaggiosa la permanenza, seppur con un ruolo meno incisivo, nel Mercosur che non la leadership nell’Alba. El autor examina el activismo de Hugo Châvez en los procesos de integración en América Latina, con especial énfasis en el Alba y en el Mercosur. Compara, por un lado, el liderazgo ejercido por Venezuela en el Alba y, por el otro, su rol secundario en el Mercosur. Muestra cómo para el Pais sea mâs ventajosa la retención, aunque con un rol de menor importancia, en el Mercosur, respecto al liderazgo en el Alba. The author examines the activism of Hugo Chàvez in the main integration processes in Latin America, Alba and Mercosur. He examines, on one hand, the leadership that Venezuela practices within the Alba and, on the other hand, the secondary role of Venezuela within Mercosur. He explains that for the country is more advantageous to remain inside the Mercosur, despite the secondary role, than to exercise the leadership within the Alba
Policy analysis and public policy in the private sector
No full textThis chapter provides a description of policy analysis in the private sector. The author introduces the topic with an informative description of the organizations that have been historically created to represent businessmen and businesswomen. Thereafter, Alba presents the main research centres that have been established by private actors with the aim of getting accurate information about political and economic trends. Alba then shows how business has developed some capacity to do policy analysis in the areas of its interest and explains the various mechanisms that businesses employ in their attempts to negotiate with state actors, and thus to influence policymaking processes.</p
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