1,720,975 research outputs found
Acroangiodermatitis (pseudo-Kaposi sarcoma) associated with verrucous hyperplasia induced by suction-socket lower limb prosthesis
No full textIncreasing use of suction-socket lower limb prostheses has been associated with an increased frequency of dermatological manifestations, linked to the fact that the skin of the amputation stump must adapt to an entirely new environment. In particular, verrucous hyperplasia and rare cases of acroangiodermatitis (pseudo-Kaposi sarcoma) have been described. We report a case of amputation stump dermatitis, clinically resembling verrucous hyperplasia, but with predominant histological aspects of acroangiodermatitis in a patient with a suction-socket lower limb prosthesis. © Blackwell Munksgaard, 2005
Non-invasive diagnosis of nodular scabies: the string of pearls sign
No full textIn nodular scabies the mites often disappear particularly after topical treatment that disintegrates them, thus not allowing the detection of the jetliner sign. As mite’s eggs are more resistant to treatment, is possible to identify the burrows filled with eggs, morphologically and ultrastructurally resembling
a ‘string of pearls’, also in nodular lesions
A case of Darier's disease successfully treated with topical tacrolimus
No full textTacrolimus is a macrolide that inhibits T-cell activation. The most extensive experience with topical tacrolimus has been in treating atopic dermatitis but it has been used in various skin diseases, including Hailey-Hailey disease, with encouraging results. We report a case of extensive Darier's disease successfully treated with topical tacrolimus, after suspension of oral isotretrinoin due to major depression
Melanoma with halo
No full textWe report this case of halo melanoma to stress that accurate clinical and dermatoscopical evaluation is essential in cases of PSL with a vitiligo-like halo, which may be misdiagnosed under the common belief that halos are associated with benign lesions
A case of reticular erythematous mucinosis treated with topical tacrolimus
No full textTacrolimus was found to be a safe and valid alternative to systemic antimalarials in our patient
Encephalocraniocutaneous lipomatosis (Haberland syndrome) with bilateral cutaneous and visceral involvement
No full textEncephalocraniocutaneous lipomatosis, or Haberland syndrome, is a rare congenital neurocutaneous disease. It is characterized clinically by unilateral lipomatous hamartomata of the scalp, eyelid, and outer globe of the eye, ipsilateral porencephalic cysts with cortical atrophy, cranial asymmetry, marked developmental delay and mental retardation. This syndrome should be distinguished from other mosaic neurocutaneous phenotypes such as as Delleman syndrome, Schimmelpenning syndrome, Goltz syndrome, Goldenhar syndrome and Proteus syndrome. Here we report a case of Haberland syndrome with bilateral involvement which underscores the extreme heterogeneity of clinical presentation of this and related syndromes
Erythema annulare centrifugum successfully treated with metronidazole
No full textWe describe the case of a 38-year-old man who came to our attention with a 2-year history of dermatitis characterized by annular erythematous plaques of different sizes on the trunk and extremities. The dermatosis started with single or multiple maculopapular erythematous lesions on the trunk and extremities. Complete remission was obtained with treatment with systemic metronidazole
A single centre melanoma thickness trend (1985-2009) in relation to skin areas accessible and non-accessible to self-inspection
No full textBackground/Objectives: Melanoma has become a major public health problem worldwide and its incidence in individuals of Caucasian origin continues to rise. The objective was to determine historical changes in thickness, melanoma proportions and anatomical site of presentation over a 25-year period in our Department. Methods: This was a historical retrospective study (January 1985 to December 2009). Only patients born and living in Italy were considered. The following parameters were evaluated: age, gender, year of diagnosis, site of primitive lesion (head, back, chest, anterior and posterior upper limbs, anterior and posterior lower limb, and acral sites) and Breslow thickness of the lesion. Results: In the 25-year period, 993 cases of melanoma were diagnosed. The total number of cases per year tripled between 1985-1989 and 1995-1999 and more than doubled between 1995-1999 and 2005-2009. Our results also revealed that thicker melanomas were more frequent in elderly patients and on parts of the body that cannot be readily self-inspected. Conclusion: The importance of observation of the posterior parts of the body is stressed, since not only did most melanomas arise in these sites but the diagnosis of lesions in these sites is often delayed
Venous ulcers of the lower limbs due to congenital thalidomide-related valve defect.
No full textA 44-year-old woman with fetal thalidomide syndrome and congenital pseudoainhum of the left big toe had a 5-year history of painful nonhealing ulcers in the left malleolar region. Venous Doppler ultrasonography showed hypoagenesis of the valve flaps of the deep and superficial venous circuit. To our knowledge, this is the first description of congenital pseudoainhum associated with fetal thalidomide syndrome. The coexistence of cutaneous ulcers in our case might be coincidental but may be related to a congenital valve defect (hypoagenesis) caused by thalidomide
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