1,721,165 research outputs found

    The Fiction and the Aesthetic Principles of Flannery O’Connor: A Study in Theory and Practice

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    Flannery O'Connor, a recent Southern writer, gives evidence in her fiction and in her statements on aesthetics that she has a message vital to modern man. This message, a faith-oriented interpretation of the meaning of man, is conveyed through three basic concepts: Reality, Redemption, and Shook. An understanding of Miss O'Connor's work must focus around this Southern writer's perspective on these key concepts and their treatment in her works. It is the purpose of this paper to clarify and to explain the meaning of these concepts and to show how they function in her work in order that Miss O'Connor's intuition1 of Reality, Redemption, and Shock may stand revealed. Reality and Redemption are the what or matter of her fiction, while Shock is the how or method of her writing.ProQuest Traditional Publishing Optio

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    The impact of cytomegalovirus infection on natural killer cell responses to vaccines

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    Vaccines are one of the most effective public health interventions, but factors influencing vaccine efficacy remain poorly understood. Natural killer (NK) cells contribute to adaptive immune responses following activation by IL-2 from memory T cells or crosslinking of CD16 by antigen-antibody complexes. Human cytomegalovirus (HCMV), a highly prevalent herpes virus, drives expansion of a mature CD56dimCD57+NKG2C+ NK cell subset, skewing the NK cell repertoire towards contact-dependent activation at the expense of cytokine sensitivity. I hypothesised that HCMV seropositivity would be associated with diminished NK cell activation during recall responses to vaccine antigens. To test this hypothesis, I first confirmed my ability to detect NK cell responses following restimulation with vaccine antigens and described differential activation by CD57-defined NK cell subsets: mature CD56dimCD57+ NK cells produced less IFN-γ than CD56bright or CD56dimCD57- NK cells, consistent with their reduced responsiveness to IL-2. Next, in a crosssectional study of 152 UK adults (36% HCMV+), I found that NK cell IFN-γ and degranulation responses to pertussis or H1N1 influenza vaccines were lower among HCMV+ individuals as compared to HCMV- individuals. The higher proportion of CD56dimCD57+NKG2C+ NK cells in HCMV+ individuals did not fully explain these impaired responses, as cells from all CD57/NKG2C-defined subsets responded less well. Finally, as I had detected lower expression of IL-18Rα on NK cells in HCMV+ individuals, I characterised pro-inflammatory cytokine interactions driving early NK cell activation and identified a central role for IL-18, due to its ability to synergise with IgG-CD16 crosslinking and common γ chain cytokines, including IL-2. This work demonstrates, for the first time, that HCMV serostatus influences heterogeneity in NK cell contributions to adaptive immunity and raises important questions regarding the impact of HCMV infection on vaccine efficacy. Furthermore, my work highlights that HCMV infection status is a major confounder of any study of human NK cell phenotype or function

    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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