118 research outputs found
Economic evaluation synthesis:time for a methodological update to support equitable decision-making
No full textEditorialAbstract is not availableYuri Jadotte, Denny John, Suzy Lockwood, Norma Bulamu, Ghislaine van Mastrigt, Luke Vale, Judith Gomersall, Dru Riddle, Sonia Hine
Direct repeat unit (dru) typing and antimicrobial resistance of methicillin-resistant Staphylococcus pseudintermedius isolated from dogs in Atlantic Canada
No full textThere are few reports investigating the characterization of methicillin-resistant Staphylococcus pseudintermedius (MRSP) in dogs in Canada and none from Atlantic Canada. The objectives of this study were to strain type MRSP isolates cultured at a regional diagnostic laboratory using direct repeat unit (dru) typing and to describe their antimicrobial resistance profiles. Ninety-four isolates recovered from dogs between 2010 and 2012 had dru typing, cluster analysis, and antimicrobial susceptibility testing done. The majority of isolates belonged to type dt11a (30.9%), dt10h (24.5%), dt9a (18.1%), and dt11af (10.6%) with the remaining 15.9% of isolates distributed among 13 dru types. The predominant dru types identified were similar in Ontario; however, cluster 9a appears to be less common in Atlantic Canada. A significant difference in the distribution of clusters among Atlantic provinces was detected (P = 0.01). Resistance to ≥ 2 non-β-lactam antimicrobials was observed in 71.4% of the isolates. The MRSP isolates from this study were notably less resistant than those reported in the literature. A more comprehensive study of the MRSP dru types could help further elucidate the distribution of this pathogen in Canada.journal article2017 Julimporte
Muslim Chinese: ethnic nationalism in the people's republic
No full textThis second edition of Dru Gladney's critically acclaimed study of the Muslim population in China includes a new preface by the author, as well as a valuable addendum to the bibliography, already hailed as one of the most extensive listing of modern sources on the Sino-Muslims
Content validity assessment of items associated with CRNA turnover: an index development study
No full textObjective: To establish content validity for instrument items associated with occupational turnover for certified registered nurse anesthetists (CRNAs).
Methods: A panel of content experts in the field of nurse anesthesiology rated items as essential, useful but not essential, and not necessary. Items which displayed statistically significant agreement among experts were retained.
Results: In total, 49 items displayed statistically significant content validity.
Conclusion: This study suggests compensation, leadership, working conditions, and the clinical practice environment are important content domains associated with CRNAs choosing to quit their jobs
Evaluation of testing as a method to assess continuing competency in nurse anesthesia practice: A systematic review
No full text
Clinical utility of pharmacogenomic testing among nurse anesthetists: A mixed-method study
No full textPharmacogenomic testing offer a unique opportunity to personalize care for individual patients. Although testing is widely available, uptake in the clinical setting is slow. This study explores why pharmacogenomic testing is not widely used among nurse anesthetists in clinical practice
Clinical Utility of Pharmacogenomic Testing to Support Prescriptive Decision Making Among Anesthesia Providers: A Mixed-Method Study
No full textAnesthesia care is delivered world wide on a daily basis. Provision of anesthesia cares for surgical, obstetrical, or pain management procedures mandate a thorough understanding of physiology, pathophysiology, and pharmacology. Nearly 4 million anesthetics are delivered in the United States each year and the impact of genetics on anesthesia care is becoming greater. Anesthesia providers make prescriptive decisions based on an individual patient\u27s disease processes, proposed surgical or therapeutic procedure, and a thorough clinical history. The age of personalized medicine is upon us and the ability to use genetic testing to help predict how a patient will respond to various medications is here. By using genetically coded single nucleotide polymorphism programming of the metabolic pathways in the liver, drugs responsiveness can be more precisely predicted and explained. This dissertation focuses on the clinical utility of genetic testing to predict drug responsiveness (pharmacogenomics) among anesthesia providers with a focus on treating acute pain. Specifically, the following research question is addressed: What is the clinical utility of pharmacogenomic testing to support prescriptive decision making among anesthesia providers. To answer this research question, a mixed-method sequential qualitative quantitative study was carried out. The conclusions of this research are (a) anesthesia providers lack knowledge concerning pharmacogenomic testing, (b) anesthesia providers are concerned about potential ethical and economic issues surrounding genetic testing, and (c) anesthesia providers perceive a potential benefit to using pharmacogenomic testing as it relates to making prescriptive decisions. Further work is necessary to more carefully refine the instrument used to measure clinical utility as well as future intervention work aimed at increasing anesthesia provider knowledge about pharmacogenomic testing
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No full textINTRODUCTION: Plants have proved to be significant natural resources for medicines; documentation of their use in medicine originates from ancient times. Ethnobotanical and ubiquitous plants provide a rich resource for natural dru
A preliminary investigation of welfare migration induced by time limits
No full textStudies on welfare programs in the United States have identified three types of welfare migration (employment, benefit, and amenity-related). This paper introduces a fourth type of migration induced by welfare time limits. After a welfare-dependent family runs out of benefits, it is possible for them to reset the Temporary Assistance for Needy Families time clock by crossing state lines to extend their benefits. Our theoretical results suggest that the likelihood of migration increases if the migration distance is small or the gain from the move is large. We hypothesize that, ceteris paribus, families migrating in order to extend their benefits will minimize the distance they migrate, and will be likely to move into the nearest state, especially into counties just across the state border. We utilize macro data at the county level to look for evidence of time-limit induced migration. Estimates indicate that time limits may be associated with an increase in welfare migration.welfare reform; migration
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