367 research outputs found
Global Health at Thomas Jefferson University: A Perspective from 40,000 Feet
Richard J. Derman, MD, MPH, FACOG
Richard J. Derman was appointed the first Associate Provost of the Office of Global Affairs, Director of Global Health Research, and Professor of Obstetrics and Gynecology at Thomas Jefferson University in May 2016. He has joined the Jefferson family to help build a sustainable academic model for our Global Jefferson enterprise.
Dr. Derman’s career has focused on research and clinical care, addressing underserved women, both in the US and in under-resourced countries. He has risen to high levels of operating responsibility at both global health agencies and as an endowed chair and associate dean within US academic institutions. Dr. Derman has served as a consultant to NGOs and to the World Health Organization. The results of his collaborative maternal child health research with partners in Belgaum, has been formally recognized by DHHS, NIH, USAID and the government of India.
Before completing his residency in obstetrics and gynecology at Cornell University, the New York Lying-In Hospital, and his master’s in public health degree from Johns Hopkins University, Dr. Derman served as a Peace Corps physician in India and a medical director of the Peace Corps in Washington, D.C. Dr. Derman served as medical director and Principal Investigator at the Center of Excellence in Women’s Health at University of Illinois and University of Missouri, Kansas City, as well as Christiana Care Health Systems. He was the inaugural Marie E. Pinizzotto, MD, Endowed Chair of Obstetrics and Gynecology at Christiana Care Health System.
Dr. Derman is a principal investigator of the Global Research Network for Women’s and Children’s Health, funded by the National Institutes of Health, and is involved in research funded by the World Health Organization and the Gates Foundation. He has published more than 100 articles in indexed, peer-reviewed journals and is a leading advocate for outcomes research in women’s health, currently serving as founding President of the Society for Health Outcomes in Women
Welcome and Opening Remarks
Richard J. Derman, MD, MPH, FACOG
Richard J. Derman was appointed the first Associate Provost of the Office of Global Affairs, Director of Global Health Research, and Professor of Obstetrics and Gynecology at Thomas Jefferson University in May 2016. He has joined the Jefferson family to help build a sustainable academic model for our Global Jefferson enterprise.
Dr. Derman’s career has focused on research and clinical care, addressing underserved women, both in the US and in under-resourced countries. He has risen to high levels of operating responsibility at both global health agencies and as an endowed chair and associate dean within US academic institutions. Dr. Derman has served as a consultant to NGOs and to the World Health Organization. The results of his collaborative maternal child health research with partners in Belgaum, has been formally recognized by DHHS, NIH, USAID and the government of India.
Before completing his residency in obstetrics and gynecology at Cornell University, the New York Lying-In Hospital, and his master’s in public health degree from Johns Hopkins University, Dr. Derman served as a Peace Corps physician in India and a medical director of the Peace Corps in Washington, D.C. Dr. Derman served as medical director and Principal Investigator at the Center of Excellence in Women’s Health at University of Illinois and University of Missouri, Kansas City, as well as Christiana Care Health Systems. He was the inaugural Marie E. Pinizzotto, MD, Endowed Chair of Obstetrics and Gynecology at Christiana Care Health System.
Dr. Derman is a principal investigator of the Global Research Network for Women’s and Children’s Health, funded by the National Institutes of Health, and is involved in research funded by the World Health Organization and the Gates Foundation. He has published more than 100 articles in indexed, peer-reviewed journals and is a leading advocate for outcomes research in women’s health, currently serving as founding President of the Society for Health Outcomes in Women.
Mark L. Tykocinski, MD
Mark L. Tykocinski serves as Provost and Executive Vice President for Academic Affairs, Thomas Jefferson University, and the Anthony F. and Gertrude M. DePalma Dean of Sidney Kimmel Medical College at Thomas Jefferson University. For over five years, he also served as President of Jefferson University Physicians. Before joining Jefferson in 2008, he was Professor and Chair of the Department of Pathology and Laboratory Medicine at the University of Pennsylvania School of Medicine for a decade.
Dr. Tykocinski’s research contributions have been in the fields of molecular and cellular immunology, for which he holds a series of research patents. He serves as SAB Chair for KAHR-Medical, the Israeli biotech company he founded in 2007 for fusion protein pharmaceuticals. He is Past President of the American Society for Investigative Pathology/Federation of American Societies for Experimental Biology and the Association of Pathology Chairs. He has been on the editorial boards of the American Journal of Pathology, Molecular Oncology and Genetics Research, and was honored with the Warner-Lambert/Parke-Davis Award for Outstanding Research from ASIP/FASEB. He earned a B.A. in biology magna cum laude from Yale University and his M.D. from New York University
From the History of Soviet Chekhovian Studies of the 1920s-1940s: on Two Editions of "The Portrait of Chekhov's Creativeness" by A. B. Derman
In the history of Russian chekhovian studies the works by A. B. Derman appear in two points of view that are not equally relevant today. Though Derman repeats the official interpretations of Chekhov'slegacy (for example in his critical biographical essay “A. P. Chekhov” (1939) and “Moscow in the life and work of A. P. Chekhov” (1948) and other newspaper and magazine articles, he is also the author of a curious hypothesis, with the help of which he tried to explain the dominants of Chekhov's poetics, as well as to give an exhaustive psychologicalportrait of the writer. Curious hypothesis was formulated in his monograph “The portrait of Chekhov's creativeness” and partly in its subsequently added alterations. The hypothesis lies in the idea of “disharmony”of Chekhov's character: the primacy of the rational part over the emotional one. In Derman's opinion.В статье рассматриваются две редакции монографии А. Б. Дермана "Творческий портрет Чехова"
From the History of Soviet Chekhovian Studies of the 1920s – 1940s: on Two Editions of “The Portrait of Chekhov’s Creativeness” by A. B. Derman
In the history of Russian chekhovian studies the works by A. B. Derman appear in two points of view that are not equally relevant today. Though Derman repeats the official interpretations of Chekhov’s legacy (for example in his critical biographical essay “A. P. Chekhov” (1939) and “Moscow in the life and work of A. P. Chekhov” (1948) and other newspaper and magazine articles, he is also the author of a curious hypothesis, with the help of which he tried to explain the dominants of Chekhov’s poetics, as well as to give an exhaustive psychological portrait of the writer. Curious hypothesis was formulated in his monograph “The portrait of Chekhov’s creativeness” and partly in its subsequently added alterations. The hypothesis lies in the idea of “disharmony” of Chekhov’s character: the primacy of the rational part over the emotional one. In Derman’s opinion, Chekhov’s mentally evolution was built on the conscious overcoming of the defect, including through creativity, which had reflective and compensatory functions in this process. A comparison of the latter version of “The portrait of Chekhov’s creativeness” with the first edition gives us an interesting facts for characterizing the ideological processes which were typical for soviet criticism and literary studies from 1929s to the 1940s. This article focuses on the following problems: what did literary critics write about the first edition of “The portrait of Chekhov’s creativeness”, and how Derman corrected his work, resulting in the second version of “The portrait of Chekhov’s creativeness” (1944), which he did not publish
The Limits of Empire: Imperial History in the Wake of the Transnational Turn
The participants in this panel engage with recent historiography—and with each other—to debate the limits of imperial frameworks for understanding the past. Does the current emphasis on transnational approaches to the past add to, or detract from, imperial perspectives? Does the analytical validity of imperial containers fade during the modern era? Do stark divisions between the early modern Age of Empires and the modern Age of Nations obscure more than they clarify? The three papers presented will address these questions by drawing on case studies from Nazi Germany, twentieth-century China, and the eighteenth-century Atlantic world. In doing so, they aim to initiate a discussion of imperial history that will be of interest to scholars working on diverse temporal and geographic topics. Joshua Derman (Hong Kong University of Science and Technology) examines how the opposition between land and sea empires was thematized by Carl Schmitt, a controversial German theorist whose work is often uncritically cited by historians of empire today. Schmitt’s theories of land and sea cannot provide a coherent heuristic for historians, Derman argues; rather, they represent the product of a shifting field of dubious ideological positions. Shellen Wu (University of Tennessee) proposes revising twentieth-century Chinese history by stepping back from the discourse of the nation, and refocusing attention on the geographical expanse of the modern Chinese state. The rise of geopolitics, she argues, proves an invaluable framework for understanding how the discourses of science, race, and empire combined in the twentieth century to formulate a new ideology of empire. Turning our attention to the eighteenth-century Atlantic world, Christopher Magra (University of Tennessee) argues that capitalist behavior complicates the utility of imperial analytical frameworks. Merchants living in colonial Massachusetts—like their Dutch, French, and Spanish counterparts—flouted imperial commercial regulations, traded directly with foreign entrepreneurs, and defied the efforts of imperial customs agents in their pursuit of profits. Self-interested profit maximizers certainly made use of imperial legal and political institutions, but they did so to suit their own ends. The session will be chaired and commented by Jeremy Adelman, Walter Samuel Carpenter III Professor in Spanish Civilization and Culture and Director of the Council for International Teaching and Research at Princeton University. Prof. Adelman studies the history of Latin America in comparative and world contexts. He is the author or editor of ten books, including most recently Worldly Philosopher: The Odyssey of Albert O. Hirschman, which will be published in March 2013
Gastrointestinal tolerability with ibandronate after previous weekly bisphosphonate treatment
Richard Derman1, Joseph D Kohles2, Ann Babbitt31Department of Obstetrics and Gynecology, Christiana Hospital, Newark, DE, USA; 2Roche, Nutley, NJ, USA; 3Greater Portland Bone and Joint Specialists, Portland, ME, USAAbstract: Data from two open-label trials (PRIOR and CURRENT) of women with postmenopausal osteoporosis or osteopenia were evaluated to assess whether monthly oral and quarterly intravenous (IV) ibandronate dosing improved self-reported gastrointestinal (GI) tolerability for patients who had previously experienced GI irritation with bisphosphonate (BP) use. In PRIOR, women who had discontinued daily or weekly BP treatment due to GI intolerance received monthly oral or quarterly IV ibandronate for 12 months. The CURRENT subanalysis included women receiving weekly BP treatment who switched to monthly oral ibandronate for six months. GI symptom severity and frequency were assessed using the Osteoporosis Patient Satisfaction Questionnaire™. In PRIOR, mean GI tolerability scores increased significantly at month 1 from screening for both treatment groups (oral: 79.3 versus 54.1; IV: 84.4 versus 51.0; p < 0.001 for both). Most patients reported improvement in GI symptom severity and frequency from baseline at all post-screening assessments (>90% at Month 10). In the CURRENT subanalysis >60% of patients reported improvements in heartburn or acid reflux and >70% indicated improvement in other stomach upset at month 6. Postmenopausal women with GI irritability with daily or weekly BPs experienced improvement in symptoms with extended dosing monthly or quarterly ibandronate compared with baseline.Keywords: ibandronate, osteoporosis, bisphosphonate, gastrointestina
Hedging with Stochastic and Local Volatility
We derive the local volatility hedge ratios that are consistent with a stochastic instantaneous volatility and show that this ‘stochastic local volatility’ model is equivalent to the market model for implied volatilities. We also show that a common feature of all Markovian single factor stochastic volatility models, (log)normal mixture option pricing models and ‘sticky delta’ models is that they predict incorrect dynamics for implied volatility. As a result they over-hedge the Black-Scholes model in the presence of a market skew and this explains the poor delta hedging performance of these models reported in the literature. Whilst the traditional ‘sticky tree’ local volatility models do not possess this unfortunate property, they cannot be used for pricing without exogenous and ad hoc smoothing of results. However the stochastic local volatility framework allows one to extend a good pricing model into a good hedging model. The theoretical results are supported by an empirical analysis of the hedging performance of seven models, each with different volatility characteristics, on the SP500 index skew.Local volatility, stochastic volatility, implied volatility, hedging, dynamic delta hedging, volatility dymamics
A.NAVOY'S GHAZALS TRANSLATION AND ANALYSE
The article is devoted to the French translation of A. Navoi's gazelle, which begins “Meni men istagan uz sukhbatiga arjumand etmas” and “Jonga chun derman not erdi ulmakim kayfiyati” by Hamid Ismoilov and JeanPierre Balpa. The author studied the work of translators in this area and conducted a deep analysis of the translation of a ghazal, that is, an Eastern work translated into Western European languages
- …
