1,720,966 research outputs found
<p>Infeksi herpes simpleks virus 1 rekuren dengan faktor predisposisi stres emosional</p><p>Recurrent herpes simplex virus 1 infection with predisposing factors of emotional stress</p>
No full textPendahuluan: Infeksi Herpes Simpleks Virus 1 (HSV 1) pada rongga mulut merupakan suatu penyakit yang diawali gejala prodromal yaitu demam diikuti munculnya vesikel pada wajah, mukosa mulut, dan bibir. HSV 1 bersifat laten di dalam tubuh dan dapat rekuren yang dipicu oleh paparan sinar matahari, stres emosional, kondisi imunosupresi, kelainan hormonal dan trauma saraf. Laporan kasus ini bertujuan untuk membahas infeksi HSV 1 rekuren intraoral (RIH) dengan faktor predisposisi stres emosional. Laporan kasus: Seorang perempuan 35 tahun datang ke poli Ilmu Penyakit Mulut didiagnosis RIH sejak 3 bulan sebelumnya dengan keluhan sariawan di lidah dan tenggorokan yang didahului demam. Ekstra oral tidak ditemukan kelainan sedangkan intra oral terdapat ulser, dasar kekuningan, tepi ireguler, dikelilingi eritem di lateral lidah kiri, palatum posterior, orofaring dan gingiva disertai rasa sakit. Hasil pemeriksaan darah anti HSV 1 Ig G reaktif dengan nilai 21,3 pada kunjungan dan 31,4 setelah terjadi kekambuhan. Setelah dilakukan anamnesis yang mendalam,stres emosional diduga sebagai pemicu RIH, dimana musibah yang dialami pasien mengakibatkan stres emosional yang memicu berulangnya RIH. Terapi farmakologis berupa asiklovir sistemik, obat kumur khlorheksidine glukonat, vitamin B12 serta asam folat, sedangkan pengelolaan stres diberikan sebagai terapi non farmakologi. Infeksi sembuh setelah 3 minggu. Selain terapi farmakologi, pasien ini diberikan motivasi untuk mengelola stres, terbukti pengelolaan stress dapat mempercepat penyembuhan RIH. Simpulan: Infeksi HSV 1 rekuren intraoral (RIH) dengan faktor predisposisi stres emosional dapat sembuh dengan terapi farmakologi berupa pemberian antivirus, obat kumur dan vitamin dan terapi non farmakologi pengelolaan stres dalam bentuk self suggestion menunjukkan perbaikan lesi pada minggu kedua dan sembuh pada minggu ketiga.
Kata kunci: Infeksi herpes simpleks virus 1 rekuren, stres emosional, tata laksana kasus.
ABSTRACT
Introduction: Herpes simplex virus 1 (HSV 1) infection in the oral cavity is a disease that begins with a prodromal symptom which was a fever followed by the appearance of vesicles on the face, oral mucosa, and lips. HSV 1 is latent in the human body and can be recurrently triggered by sun exposure, emotional stress, immunosuppression conditions, hormonal abnormalities, and nerve trauma. This case report was aimed to discuss the recurrent intraoral HSV 1 (RIH) infection with predisposing factors of emotional stress. Case report: A 35-years-old woman who came to the Oral Medicine Clinic was diagnosed with RIH for 3 months before with the chief complaint of oral thrush on the tongue and the throat preceded by a fever. No extraoral abnormalities were found, while intraoral examination results found an ulcer, with the yellowish base, irregular edge, surrounded by erythema lateral to the left tongue, posterior palate, oropharynx, and gingiva, and accompanied with the soreness. The result of anti-HSV 1 Ig G reactive blood tests was 21.3 at the visit and 31.4 after the recurrence. After a thorough anamnesis, emotional stress was considered as the RIH trigger, where a disaster experienced by the patient resulted in emotional stress that triggered the RIH recurrence. Pharmacological therapy was performed in the form of administration of the systemic acyclovir, chlorhexidine gluconate mouthwash, vitamin B12, and folic acid; while stress management was also given as a non-pharmacological therapy. The infection was resolved after 3 weeks. In addition to pharmacological therapy, the patient was given the motivation to manage her stress, and the stress management was proven to accelerate the RIH healing. Conclusion: Recurrent intraoral HSV 1 (RIH) infection with emotional stress as a predisposing factor can be cured with pharmacological therapy in the form of administration of antiviral, mouthwash, and vitamins, with addition of self-suggestion stress management as the non-pharmacological therapy, which were proven to improve the lesions in the 2nd week and recover in the 3rd week.
Keywords: Herpes simplex virus 1 infection, emotional stress, case management
Herbal Medicines as Adjunctive Therapy for Oral Squamous Cell Carcinoma Management: a Case Report: Obat Herbal sebagai Terapi Tambahan untuk Manajemen Karsinoma Sel Skuamosa Oral: Laporan Kasus
Full text linkOral Squamous Cell Carcinoma (OSCC) is the most frequent oral cancer. The management for OSCC are surgery, chemotherapy, and radiotherapy. Chemotherapy and radiotherapy have high toxicity and side effects, therefore effort are needed to reduce them. Several studies show that herbal medicines have anticancer effects with lower toxicity and side effects. The objective is to discuss about management of OSCC using chemotherapy and anticancer herbal medicines as adjunctive therapy. A 59-year-old man came to the oral medicine clinic complaining a painful ulcer on the right tongue since 8 months ago. The ulcer had been enlarged in the last 3 months and the tongue was difficult to be moved. He used pain relievers and aloe vera gel but there was no improvement. He smoked one pack a day since 40 years ago. Intraoral showed an irregular indurated endophytic mass with an ulcer on the right lateral of the tongue. An incisional biopsy was performed and the histopathological diagnosis was poorly differentiated OSCC. The patient was referred to the oncology department and advised for chemotherapy 6 cycles per 3 weeks. He also used herbal medicines containing Panax ginseng radix, Panax pseudoginseng radix, Ophiopogonis japonicus, Ganoderma lucidum, Ligusticum wallichii rhizoma, and Atractylodes macrocephala rhizoma. The content of these herbal medicines have anticancer and immunomodulatory effects. After the second cycle of chemotherapy, there was a significant improvement. OSCC management with chemotherapy combined with anticancer herbal medicines can increase the success of therapy and reduce the side effects of chemotherapy
<p>Kondisi kesehatan gigi dan mulut siswa SDK Yahya</p><p>Oral health conditions of the Yahya Christian Elementary School students</p>
No full textPendahuluan: Rongga mulut terdiri dari jaringan lunak maupun jaringan keras, serta merupakan anggota tubuh yang penting untuk dijaga seperti anggota tubuh lainnya. Tujuan penelitian ini adalah untuk mengetahui kondisi kesehatan gigi dan mulut siswa SDK Yahya. Metode: Jenis penelitian deskriptif. Data penelitian diambil dari formulir kesehatan gigi dan mulut siswa SDK Yahya dan disajikan dalam bentuk tabel distribusi frekuensi. Hasil: Sebagian besar siswa mempunyai gingiva, mukosa bukal, mukosa labial, frenulum, lidah, dan saliva yang normal serta seluruh siswa mempunyai palatum keras dan lunak yang normal. Persentase karies, tambalan dan gigi yang hilang pada siswa tergolong kecil dan nilai oral higyenenya nilai yang kecil. Keadaan ini menunjukkan bahwa umumnya siswa mempunyai kesehatan jaringan lunak dan keras yang baik serta keadaan oral hygiene yang baik. Simpulan: Kondisi kesehatan gigi dan mulut siswa SDK Yahya mayoritas tergolong dalam kondisi normal dengan oral hygiene dalam kondisi baik.
Kata kunci: Kesehatan gigi dan mulut, siswa SD.
ABSTRACT
Introduction: The oral cavity consists of both hard and soft tissues that are vital to be maintain like the other part of the body. Improving knowledge and behavior which was given since school age could overcome the incidence of oral health problems. Tujuan penelitian ini adalah untuk mengetahui kondisi kesehatan gigi dan mulut siswa SDK Yahya. Methods: This was a descriptive study using oral health form of both hard and soft tissues of students from Yahya Christian Elementary School. Results: This study revealed that most students had normal gingiva, buccal mucosa, labial mucosa, frenulum, tongue and saliva, and also normal palatum durum and molle. The percentage of cavities, fillings and tooth-loss on the students was considered as small. Such findings demonstrated that in general, the students had decent integrity of both soft and hard oral tissues. Conclusion: Oral health conditions of the Yahya Christian Elementary School students were generally observed in the normal state.
Keywords: Oral health condition, elementary school students
Fractionation of Red Pomegranate (Punica granatum L.) Seed Ethanolic Extracts for Identifying Active Compounds
No full text<p>Necrotizing ulcerative stomatitis mimicking erythema multiforme pada pasien dengan HIV seronegatif</p><p>Necrotizing ulcerative stomatitis mimicking erythema multiforme in HIV seronegative patients</p>
No full textABSTRAK
Pendahuluan: Necrotizing ulcerative stomatitis (NUS) merupakan inflamasi akut yang ditandai destruksi, ulserasi serta nekrosis epitel, jaringan ikat dan papila. Umumnya terjadi pada pasien malnutrisi dan Human Immunodeficiency Virus (HIV) seropositif. Lesi awal berupa necrotizing gingivitis kemudian berkembang menjadi necrotizing periodontitis, selanjutnya menjadi NUS. Gambaran klinis kasus NUS kadang serupa dengan Erythema multiforme (EM), sehingga perlu dilakukan pemeriksaan penunjang yang dapat menegakkan diagnosa dengan tepat. Tujuan laporan kasus ini melaporkan cara menegakkan diagnosis NUS yang menyerupai EM secara tepat pada pasien dengan suspek infeksi HIV. Laporan kasus: Pasien laki-laki berusia 49 tahun dirujuk ke departemen Ilmu Penyakit Mulut dengan diagnosis EM disertai suspek terinfeksi HIV. Keluhan utama berupa rasa nyeri disertai sariawan pada lidah dan bibir bagian dalam. Pemeriksaan ekstraoral tidak ada kelainan, pada intraoral ditemukan ulser multipel dilapisi sloughing kekuningan pada mukosa labial, mukosa bukal, dorsal lidah, lateral lidah dan ventral lidah. Gingiva anterior rahang bawah terdapat lesi ulseratif disertai jaringan nekrosis. Pemeriksaan darah menunjukkan penurunan hematokrit, peningkatan leukosit, serta negatif pada pemeriksaan tes HIV. Actinomyces naeslundii ditemukan pada pemeriksaan mikrobiologi. Ditegakkan diagnosis NUS dan terapi yang diberikan amoxicillin 500mg, metronidazol 500mg, chlorhexidine gluconate 0,2% dan asam folat. Lesi oral mengalami perbaikan dalam 2 minggu. Simpulan: Lesi oral mengalami perbaikan secara signifikan setelah kontrol ketiga atau seminggu dari kunjungan pertama, pasien sudah dapat makan tanpa rasa nyeri. Gambaran klinis lesi mukosa oral yang khas, serta pemeriksaan penunjang mikrobiologi berperan dalam menunjang diagnosis NUS. Tes HIV perlu dilakukan untuk mengkonfirmasi status infeksi HIV pada pasien. Dokter gigi sebaiknya mengenali tanda dan gejala NUS, sehingga dapat menegakkan diagnosis dan memberikan terapi adekuat serta mencegah meluasnya kerusakan jaringan.
Kata kunci: Human immunodeficiency virus, lesi oral, necrotizing ulcerative stomatitis, erythema multiforme.
ABSTRACT
Introduction: Necrotizing ulcerative stomatitis (NUS) is an acute inflammation characterised by destruction, ulceration, and necrosis of the epithelium, connective tissue, and papillae. Generally occurs in malnourished and Human Immunodeficiency Virus (HIV) seropositive patients. The initial lesion is found in the form of necrotizing gingivitis then developed into necrotizing periodontitis, which later became NUS. The clinical feature of NUS sometimes similar to the erythema multiforme (EM); thus, it is necessary to conduct investigations to make the diagnosis correctly. This case report was aimed to report on how to properly diagnose an EM-like NUS in a patient with suspected HIV infection. Case report: A 49-years-old male patient referred to the Oral Medicine department with an EM diagnosis with suspected HIV infection. The main complaint is pain accompanied by mouth sores on the tongue and inner lips part. Extraoral examination showed no abnormality, multiple ulcers coated with yellowish sloughing on the labial mucosa, buccal mucosa, dorsal tongue, lateral tongue, and ventral tongue. The anterior mandibular gingiva had ulcerative lesions with tissue necrosis. Blood tests showed a decrease in hematocrit, an increase in leukocytes, and a negative result of the HIV test. Actinomyces naeslundii was found on microbiological examination. Diagnosis of NUS was confirmed, and therapy given were amoxicillin 500 mg, metronidazole 500 mg, chlorhexidine gluconate 0.2%, and folic acid. The oral lesions improved within two weeks. Conclusion: Oral lesions improved significantly after the third control in a week from the first visit, the patient was able to eat without pain. The clinical feature of typical oral mucosal lesions, as well as microbiological examinations, play a role in supporting the diagnosis of NUS. An HIV test needs to be carried out to confirm the HIV infection status of the patient. Dentists should recognise the signs and symptoms of NUS to determine a diagnosis, provide adequate therapy, and prevent the spread of tissue damage.
Keywords: Human immunodeficiency virus, oral lesions, necrotizing ulcerative stomatitis, erythema multiforme
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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