1,734,748 research outputs found
Rosengarten, das ist: fünfundvierzig katholische Predigten
No full textAn jetzo aber ... in Druck verfertiget: Durch den Ehrwürdigen in Gott Vattern vnd Herrn, Herrn Qvirinvm Rest, Abbt dess würdigen vnnd berümbten Closters Tegernsee, im Hertzogthumb Bayrn gelegenTitelvignette, Titelblatt in Rot- und SchwarzdruckBogensignaturen: *-***, A-Z, a-z, Aa-Zz, Aaa⁴, Bbb²Aus dem Vorbesitz des Klosters Rheinau.M Mit Verbalexlibris auf dem Titelblatt. Auf dem Vorsatzblatt hs. Besitzvermerk von Kaspar Trinckler
REST-Neo4p v0.3020
No full textREST::Neo4p provides a Perl 5 object framework for accessing and manipulating a Neo4j graph database server via the Neo4j REST API. Its goals are
(1) to make the API as transparent as possible, allowing the user to work exclusively with Perl objects, and
(2) to exploit the API's self-discovery mechanisms, avoiding as much as possible internal hard-coding of URLs
REST-típusú webszolgáltatások megvalósítása Java-ban
No full textA diplomamunka céljának tűztem ki, hogy készítsek egy olyan alkalmazást, amely teljes mértékben megfelel a REST által definiált elveknek. Kicsit kutakodva több lehetséges megvalósítási lehetőségre is bukkantam, akkor határoztam el, hogy két megoldást is szeretnék körbejárni és bemutatni. Az egyik megoldás lesz a JAX-RS, a másik pedig a Spring keretrendszer által biztosított REST megvalósítás.MSc/MAProgramtervező informatiku
Changes in intervertebral disc morphology persist 5 mo after 21-day bed rest
No full textAs part of the nutrition-
countermeasures (NUC) study in Cologne, Germany in 2010,
seven healthy male subjects underwent 21 days of head-down tilt bed
rest and returned 153 days later to undergo a second bout of 21-day
bed rest. As part of this model, we aimed to examine the recovery of
the lumbar intervertebral discs and muscle cross-sectional area (CSA)
after bed rest using magnetic resonance imaging and conduct a pilot
study on the effects of bed rest in lumbar muscle activation, as
measured by signal intensity changes in T2-weighted images after a
standardized isometric spinal extension loading task. The changes in
intervertebral disc volume, anterior and posterior disc height, and
intervertebral length seen after bed rest did not return to prebed-rest
values 153 days later. While recovery of muscle CSA occurred after
bed rest, increases (P 0.016) in multifidus, psoas, and quadratus
lumborum muscle CSA were seen 153 days after bed rest. A trend was
seen for greater activation of the erector spinae and multifidus muscles
in the standardized loading task after bed rest. Greater reductions of
multifidus and psoas CSA muscle and greater increases in multifidus
signal intensity with loading were associated with incidence of low
back pain in the first 28 days after bed rest (P 0.044). The current
study contributes to our understanding of the recovery of the lumbar
spine after 21-day bed rest, and the main finding was that a decrease
in spinal extensor muscle CSA recovers within 5 mo after bed rest but
that changes in the intervertebral discs persist
Resistive vibration exercise during bed-rest reduces motor control changes in the lumbo-pelvic musculature
No full textTo understand the effects of a resistive vibration exercise (RVE) countermeasure on changes in lumbopelvic
muscle motor control during prolonged bed-rest, 20 male subjects took part in the Berlin Bed-Rest
Study (in 2003âÂÂ2005) and were randomised to a RVE group or an inactive control group. Surface electromyographic
signals recorded from five superficial lumbo-pelvic muscles during a repetitive knee movement
task. The task, which required stabilisation of the lumbo-pelvic region, was performed at multiple
movement speeds and at multiple time points during and after bed-rest. After excluding effects that
could be attributed to increases in subcutaneous fat changes and improvements in movement skill, we
found that the RVE intervention ameliorated the generalised increases in activity ratios between movement
speeds (p 6 0.012), reductions in lumbo-pelvic extensor and flexor co-contraction (p = 0.058) and
increases in root-mean-square electromyographic amplitude (p = 0.001) of the lumbar erector spinae
muscles. Effects of RVE on preventing increases in amplitude-modulation (p = 0.23) of the lumbar erector
spinae muscles were not significant. Few significant changes in activation-timing were seen. The RVE
intervention during bed-rest, with indirect loading of the spine during exercise, was capable of reducing
some, but not all, motor control changes in the lumbo-pelvic musculature during and after bed-rest
Prevention of bone loss during 56 days of strict bed rest by side-alternating resistive vibration exercise
No full textBed rest is a recognized model for muscle atrophy and bone loss in space flight and in clinical medicine. We
hypothesized that whole body vibration in combination with resistive exercise (RVE) would be an effective
countermeasure.
Twenty healthy male volunteers underwent horizontal bed rest for 56 days and were randomly assigned
either to a group that performed RVE 11 times per week or to a group that underwent bed rest only (Ctrl).
Bone mineral content (BMC) was assessed by peripheral quantitative computed tomography (pQCT) in the
tibia and the radius and by dual x-ray absorptiometry (DXA) in the hip and lumbar spine at baseline and at
regular intervals during bed rest and a 12-month follow-up.
RVE appeared to protect muscle size and function, and it also prevented bone loss (p-values between b0.001
and 0.01). Bone losses were largest in the distal tibia epiphysis, where BMC declined from 421.8 mg/mm (SD
51.3) to 406.6 mg/mm (SD 52.7) in Ctrl, but only from 411.1 mg/mm (SD 56.6) to 409.6 mg/mm (SD 66.7)
in RVE. Most of the BMC losses were recovered by 12-month follow-up. Analyses showed that the epiphyseal
cortex, rather than spongiosa, depicted the most pronounced changes during bed rest and recovery.
These results suggest that the combined countermeasure applied in this study is effective to prevent bone
losses from the tibia. This underlines the importance of mechanical usage for the maintenance of the human
skeleton
Changes in lower extremity muscle function after 56 days of bed rest
No full textPreservation of muscle function, known to decline in microgravity and simulation (bed rest), is important for successful spaceflight missions. Hence, there is great interest in developing interventions to prevent musclefunction
loss. In this study, 20 males underwent 56 days of bed rest.
Ten volunteers were randomized to do resistive vibration exercise (RVE). The other 10 served as controls. RVE consisted of muscle contractions against resistance and concurrent whole-body vibration.
Main outcome parameters were maximal isometric plantar-flexion force (IPFF), electromyography (EMG)/force ratio, as well as jumping power and height. Measurements were obtained before and after bed rest, including a morning and evening assessment on the first day of recovery from bed rest. IPFF (-17.1%), jumping peak power (-24.1%), and height (-28.5%) declined (P < 0.05) in the control
group. There was a trend to EMG/force ratio decrease (-20%; P < 0.051). RVE preserved IPFF and mitigated the decline of countermovement jump performance (peak power -12.2%; height -14.2%). In both groups, IPFF was reduced between the two measurements of the first day of reambulation. This study indicates that bed rest and countermeasure exercises differentially affect the various functions of skeletal muscle. Moreover, the time course during recovery needs to
be considered more thoroughly in future studies, as IPFF declined not only with bed rest but also within the first day of reambulation. RVE was effective in maintaining IPFF but only mitigated the decline in jumping performance. More research is needed to develop countermeasures that maintain muscle strength as well as other muscle functions including power
Alkalmazásfejlesztés REST alapokon
No full textDolgozatom témájaként egy olyan web-alkalmazás elkészítését tűztem ki, amely megfelelően alkalmazkodik a különböző képernyő felbontásokhoz, kellőképpen interaktív, eseményvezérelt, a legmodernebb technológiákat alkalmazza, és eleget tesz a REST architektúra megszorításainak.
A TicketRadar fejlesztési folyamatainak bemutatása során nyilvánvalóvá válik, hogy a számos modern technológia segítségével mily módon lehet könnyen és gyorsan webalkalmazásokat fejleszteni. A felhasznált rendszerekről megállapítható, hogy minden egysége egy-egy jól megtervezett munka eredménye.
Munkám során rengeteg új szemléletmódot ismertem meg – REST architektúra, MVC minta – és már magabiztosan használom a tárgyalt rendszereket. Symfony 2 és Angular JS keretrendszerek használatakor rájöttem, hogy mennyire egyszerűen megoldhatóak, olyan feladatok melyek korábbi webfejlesztési tapasztalataim során nehézséget okoztak.
A REST architektúrának köszönhetően sikerült teljesen szétválasztanom a szerver- és kliens oldali feladatokat, valamint az MVC mintának köszönhetően a felhasználói felületek és a működés szétválasztását is sikerült megoldanom, így egy igazán flexibilis és jól bővíthető alkalmazást hoztam létre.
Szakdolgozatomban részletesen, kódokkal szemléltetve is bemutattam, hogyan lehet Symfony 2 segítségével szerveroldali, AngularJS segítségével pedig kliensoldali alkalmazásokat létrehozni, valamint bemutattam e két rendszer integrálását és a további hasznos modul telepítését, használatát, mint pl. a Jade, amely leegyszerűsítette a HTML kódok írását, a Coffee Script, amely megkönnyítette a JavaScript fejlesztést, vagy a Bootstrap, amely segítette egy egyszerű, letisztult és responsive interfész kialakítását.
Természetesen az elkészített alkalmazásomhoz még rengeteg fejlesztési ötletem van, mint pl. a regisztráció beiktatása, egy felhasználó kezelés kialakítása, valamint a RESTful kialakítás, de ezidáig is sikerült olyan szintre fejlesztenem, amely már éles környezetben is megállja a helyét. További hiányosság még az adatbázis mérete, ami idővel bővülni fog nem csak az általam feltöltött, hanem a látogatók által beküldött adatokkal is.
Úgy gondolom, hogy sikerült egy olyan alkalmazást készítenem, amely nagyban segítheti a TicketRadar felhasználók országszintű tájékozódását a mindennapi rohanó élet során.BSc/BAMérnök Informatiku
Anatomical sector analysis of load-bearing tibial bone structure during 90 days bed rest and 1- year recovery
No full textThe aim of this study was to investigate whether the bone response to long bed rest–related immobility and during subsequent recovery differed at anatomically different
sectors of tibial epiphysis and diaphysis. For this study, peripheral quantitative tomographic (pQCT) scans obtained from a previous 90-day Long Term Bed Rest intervention were preprocessed with a new method based on statistical approach and re-analysed sector-wise. The pQCT was performed on 25 young healthy males twice before the bed rest, after the bed rest and after 1-year follow-up. All men underwent a strict bed rest intervention, and in addition, seven of them received pamidronate treatment and nine did flywheel exercises as countermeasures against disuse-related
bone loss. Clearly, 3–9% sector-specific losses in trabecular density were observed at the tibial epiphysis on average. Similarly, cortical density decreased in a sectorspecific
way being the largest at the anterior sector of tibial diaphysis. During recovery, the bed rest–induced bone losses were practically restored and no consistent sector-specific modulation was observed in any subgroup. It is concluded
that the sector-specific analysis of bone cross-sections has potential to reveal skeletal responses to various interventions that cannot be inferred from the average analysis of the whole bone cross-section. This approach is considered also useful for evaluating the bone responses from the biomechanical point of view
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