1,722,799 research outputs found
Interactions among dendritic cells, macrophages, and epithelial cells in the gut: implications for immune tolerance
No full textThe intestine is described as an immune privileged site where immunoregulatory mechanisms simultaneously defend against pathogens, yet preserve tissue homeostasis to avoid immune-mediated pathology in response to environmental challenges. Additionally, tolerance to ingested antigens promotes the development of systemic unresponsiveness towards the same antigens. It is increasingly clear that this tolerance is a complex process that derives from the coordinated action of both canonical immune and non-immune cells at mucosal sites, including dendritic cells, macrophages and epithelial cells. Recent evidence suggests that dysregulation in gut-induced tolerance and commensal bacterial handling affects both local and systemic compartments and contributes to autoimmune disease. Understanding how tolerance is achieved at mucosal sites may thus be exploited to re-establish tissue homeostasis. © 2008 Elsevier Ltd. All rights reserved
Personalized models for facial emotion recognition through transfer learning
Full text linkEmotions represent a key aspect of human life and behavior. In recent years, automatic recognition of emotions has become an important component in the fields of affective computing and human-machine interaction. Among many physiological and kinematic signals that could be used to recognize emotions, acquiring facial expression images is one of the most natural and inexpensive approaches. The creation of a generalized, inter-subject, model for emotion recognition from facial expression is still a challenge, due to anatomical, cultural and environmental differences. On the other hand, using traditional machine learning approaches to create a subject-customized, personal, model would require a large dataset of labelled samples. For these reasons, in this work, we propose the use of transfer learning to produce subject-specific models for extracting the emotional content of facial images in the valence/arousal dimensions. Transfer learning allows us to reuse the knowledge assimilated from a large multi-subject dataset by a deep-convolutional neural network and employ the feature extraction capability in the single subject scenario. In this way, it is possible to reduce the amount of labelled data necessary to train a personalized model, with respect to relying just on subjective data. Our results suggest that generalized transferred knowledge, in conjunction with a small amount of personal data, is sufficient to obtain high recognition performances and improvement with respect to both a generalized model and personal models. For both valence and arousal dimensions, quite good performances were obtained (RMSE = 0.09 and RMSE = 0.1 for valence and arousal, respectively). Overall results suggested that both the transferred knowledge and the personal data helped in achieving this improvement, even though they alternated in providing the main contribution. Moreover, in this task, we observed that the benefits of transferring knowledge are so remarkable that no specific active or passive sampling techniques are needed for selecting images to be labelled
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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