26 research outputs found

    Comparison of Sirolimus Versus Paclitaxel Eluting Stents for Treatment of Coronary In-Stent Restenosis

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    In patients with in-stent restenosis (ISR) inside bare metal stents, drug-eluting stents reduce the recurrence of restenosis compared with balloon angioplasty. However, few data are available about this therapeutic modality in the case of diffuse restenosis. The aim of this study was to evaluate the immediate and mid-term outcome of sirolimus- and paclitaxel-eluting stent implantation in diffuse ISR and determine the predictors of clinical and angiographic restenosis recurrence. A series of 161 consecutive patients with 194 diffuse ISR lesions (>10 mm) treated with drug-eluting stent implantation were evaluated. Major adverse cardiac events were defined as death, myocardial infarction, and the need for target lesion revascularization. During a mean follow-up of 8.2 ± 3.4 months, the cumulative incidence of major adverse cardiac events was 19% in the SES group and 24% in the PES group (p = 0.56). Angiographic follow-up was performed in 80% of the lesions. The overall restenosis rate was 22% and was not significantly different between lesions treated with sirolimus-eluting (20%) or paclitaxel-eluting (25%, p = 0.55) stents. The incidence of restenosis was higher in diabetics (32%) than in nondiabetics (16%, odds ratio 2.5, 95% confidence interval 1.1 to 5.5, p = 0.02). By multivariate analysis, diabetes was confirmed to be the only independent predictor of recurrent restenosis (odds ratio 3.53, 95% confidence interval 1.39 to 9.02, p = 0.008). In conclusion, drug-eluting stent implantation for diffuse ISR is associated with acceptable clinical and angiographic results. The association of diffuse restenosis and diabetes mellitus is an unfavorable condition leading to a high risk of recurrence. © 2006 Elsevier Inc. All rights reserved

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    The impact of the COVID-19 pandemic on the quantity and quality of sleep in medical university students

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    Rogacka, Karolina, Pyrak, Bartłomiej, Kędziora–Kornatowska, Kornelia. The impact of the COVID-19 pandemic on the quantity and quality of sleep in medical university students. Journal of Education, Health and Sport. 2022;12(10):143-152. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.10.017 https://apcz.umk.pl/JEHS/article/view/40358 https://zenodo.org/record/7178269 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 15.09.2022. Revised: 20.09.2022. Accepted: 21.09.2022. The impact of the COVID-19 pandemic on the quantity and quality of sleep in medical university students Karolina Rogacka1, ORCID: 0000-0001-9925-7305, [email protected] Bartłomiej Pyrak2, ORCID: 0000-0003-3489-2353, [email protected] Kornelia Kędziora–Kornatowska1, ORCID: 0000-0003-4777-5252, [email protected] 1Department of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Torun, Poland 2Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Poland Abstract Introduction: In order to overpower COVID-19 pandemic a number of security measures have been taken, including limiting of leaving people's place of residence, which is associated with increased social isolation. For students an additional change resulting from the current epidemiological situation is the transition to remote learning which is related with increased time spent in front of a computer or smartphone screen. The aim of the study: The aim of the study was to determine whether the COVID-19 pandemic affects the quality and quantity of sleep in a group of medical students. Materials and methods: Survey search using author-made questionnaire was conducted. Questionnaire included questions about quality and quantity of sleep before and after COVID-19 pandemic outbreak. Collected data was then transformed for statistical purposes and the correlations were examined using Wilcoxon test (before vs after pandemic) or Mann-Whitney U-test (men vs women). Results: Comparing the situation before the pandemic to the present one, statistically significant increase in difficulty in falling asleep in the study group was observed (p=0,008). A statistically significant sleep duration change was observed (the mean increased from 7,09 to 7,53, p<<0.05). Students also go to bed later (p<<0.05) and wake up later (p<<0.05). Students also complained about waking up more frequently at night (p=0,006). The respondents rate their current sleep quality worse than before the pandemic (p=0,039). Conclusions: Sleep quality in the group of medical students deteriorated during the pandemic, while the amount of sleep increased. Since the introduction of remote learning, the time of using electronic devices has significantly increased. The obtained results may be used for further research on the impact of the COVID-19 pandemic and remote learning on the quality and quantity of sleep. Key words: COVID-19, sleep hygiene, medical student

    Digital skills in the workplace – from the employees’ and supervisors’ perspective

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    Kompetencje cyfrowe – ze względu na relacyjny i relatywny charakter – od dawna stanowią wyzwanie dla badaczy chcących stworzyć ich ramowy katalog. Wraz z rozwojem technologii i zmianami w środowisku pracy, zadanie to staje się trudniejsze, a gradacja kompetencji cyfrowych – coraz mniej klarowna. Podobne wątpliwości towarzyszą pracodawcom i menedżerom: Co to znaczy, że pracownik ma kompetencje cyfrowe? Jak zweryfikować ich poziom? Jak sprawdzić, czy posiadane przez pracownika e-umiejętności pomogą mu w realizacji powierzonych zadań? Od pandemii COVID-19 jeszcze mocniej podkreśla się wagę kompetencji cyfrowych pracowników. Wiele firm dopasowało sposób działania do nowych warunków (praca zdalna, praca hybrydowa). Pomimo licznych opracowań merytorycznych trudno doszukać się ujednoliconego sposobu badania kompetencji cyfrowych we współczesnych miejscach pracy. Autorka w artykule przedstawia wyniki badań kompetencji cyfrowych pracowników w wybranej firmie finansowej. Podstawą merytoryczną był model DigComp, dzięki któremu zdiagnozowano kompetencje cyfrowe w poszczególnych, konkretnych obszarach (badania ilościowe). W drugiej części badania porównano deklaracje pracowników z opisem ich kompetencji cyfrowych dokonanym przez przełożonych (badania jakościowe) na poziomie operacyjnym – w środowisku zawodowym. W wyniku badań odkryto rozbieżności pomiędzy poczuciem posiadania kompetencji cyfrowych w odczuciu pracowników oraz w opinii menedżerów w zakresie cybersecurity, wykorzystania narzędzi cyfrowych w usprawnianiu pracy, jak również w zachowaniu work-life balance.For a long time digital skills, due to their relational and relative nature, have been a challenge for researchers trying to create a framework catalogue of these competences. As technology develops and the working environment changes, this task is becoming increasingly difficult and the gradation of digital skills is getting less and less clear. Employers and managers have similar doubts: What does it mean that an employee has digital skills? How can you assess their level? How can you check whether an employee’s digital skills will help them fulfil their tasks? Since the pandemic, emphasis has been put on the importance of the digital competences of employees, with many companies adapting the way they operate to the new conditions (remote work, hybrid work). Despite many existing compilations it is difficult to find a unified method of assessing digital skills in modern workplaces. In this article the author presents the results of research on digital skills of employees of a financial company. The DigComp model was applied as the technical basis of the research, which allowed for a diagnosis of digital skills in specific areas (qualitative research). The other part of the research compares employees’ claims with their supervisor’s description of their digital skills (qualitative research) on the operational level – in a professional environment. The research showed discrepancies in the perception of employees’ digital skills related to cybersecurity, the use of digital tools for streamlining work processes, as well as keeping a work-life balance

    Fibromyalgia in the light of different methods of treatment

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    SZOTA, Maciej, MODLIŃSKA, Aleksandra, ROGACKA, Karolina & KĘDZIORA–KORNATOWSKA, Kornelia. Fibromyalgia in the light of different methods of treatment. Journal of Education, Health and Sport. 2022;12(12):331-337. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.12.050 https://apcz.umk.pl/JEHS/article/view/41082 https://zenodo.org/record/7474838 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 12.11.2022. Revised: 21.12.2022. Accepted: 21.12.2022. Fibromyalgia in the light of different methods of treatment Maciej Szota1, ORCID: 0000-0001-6611-675X, [email protected] Aleksandra Modlińska2, ORCID: 0000-0003-3425-7202, [email protected] Karolina Rogacka1, ORCID:0000-0001-9925-7305, [email protected] Kornelia Kędziora–Kornatowska1, ORCID:0000-0003-4777-5252, [email protected] 1Department of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń 2 Department of Exercise Physiology and Functional Anatomy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń Abstract Introduction and purpose: Fibromyalgia is a disease with many symptoms that are difficult to treat. The most troublesome element is muscle, bone or joint pain. Importantly, the diagnosis of this disease is based on the physical examination and the subjective examination, which shows that there are no laboratory tests to confirm its presence. Public awareness of fibromyalgia is negligible, while more research is needed on the treatment of this disease and the possible alternatives associated with it. The aim of this study was to analyze the available literature on the basis of the PubMed scientific database, considering only scientific articles that were published within the last 5 years. The following keywords were used: fibromyalgia and physiotherapy, fibromyalgia and cannabis, fibromyalgia and cytokines. Description of the state of knowledge: Treatments related to cannabinoids and physiotherapy are still developing fields of knowledge. More than 40 papers related to the topic of the study were used for the review. The need for further research is apparent, especially randomized studies in which allocation to an experimental or control group is completely random. The question of investigating the long-term effectiveness of a given treatment is also not negligible, as many studies do not have a so-called follow-up. Conclusion: Cannabinoids are effective in the treatment of complaints associated with fibromyalgia. Exercise, laser therapy and acupuncture reduce pain and improve quality of life in patients with fibromyalgia. More research on this disease is needed, especially with larger patient groups. Key words: fibromyalgia; physiotherapy; cannabis; cytokine

    Resistant hypertension in a patient with chronic type B aortic dissection. A selective indication for renal artery denervation treatment

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    In patients surviving aortic dissection, refractory hypertension may represent a major clinical problem. Therefore, blood pressure control is extremely crucial in this setting, to avoid aortic diameter expansion with the inherent risk of rupture (1). Percutaneous renal denervation has emerged as an effective additional treatment in the management of resistant hypertension. However, despite the technology is appealing in patients with previous aortic dissection and its feasibility and safety already described in a small case series (2), the anatomical setting may be an obstacle to successfully treat patients not addressed to endovascular stent-graft placement. To the best of our knowledge, this treatment has been previously performed in a single case of chronic aortic type B dissection presenting with dyspnoea, progressive chest- and abdominal-pain (3). Here we describe a case of a 51-year-old man with a persistent treatment-resistant hypertension despite multiple medications, after a stabilized type B aortic dissection precipitated by a hypertensive crisis.. Catheter-based renal artery denervation was planned using the Vessix Reduce™ Renal Denervation System (Boston Scientific, Marlborough, MA) as the ablation device. It consists of an over-the-wire low-pressure balloon catheter (diameter ranges 4-7 mm) with an array of bipolar radiofrequency electrodes delivering 1 Watt energy at 68° C in 30 seconds, through a temperature-controlled algorithm (Figure 3). The patient received heparin 5000 U i.v. and intravenous anxiolytics and narcotics to manage intraprocedural diffuse visceral pain, during energy delivery. Renal denervation was performed by right femoral approach. The right renal artery access was gained with a .014” Hi-Torque Extra S’port guide-wire advanced from the false towards the true vessel lumen. The manoeuver, was made possible with the support of a steerable coronary microcatheter which allowed for a superselective angiography confirming the proper position. The Vessix Reduce™ catheter (7.0 mm) was then advanced into a 8-F renal double curve guiding catheter (Cordis Corporation, FL, USA) after selective cannulation with the guiding catheter and a single ablation was performed in the right renal artery, without any procedural complication . Thereafter, a left renal artery selective cannulation was performed under fluoroscopy and followed by positioning of the Vessix catheter at the mid and ostial portion of the vessel for ablation. Office blood pressure follow-up measurements, available at one, six, and twelve-months, showed a pronounced and sustained decrease at each time point when compared to baseline (-35 mmHg/-15 mmHg). This trend was furtherly confirmed by the home blood pressure measurements (- 24 mmHg/-13 mmHg). A 60% reduction of blood pressure values above 140/90 mmHg was observed on 24-hour ambulatory pressure monitoring at 12-month follow-up

    Favorable long-term outcome after drug-eluting stent implantation in nonbifurcation lesions that involve unprotected left main coronary artery: a multicenter registry

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    BACKGROUND: The presence of a lumen narrowing at the ostium and the body of an unprotected left main coronary artery but does not require bifurcation treatment is a class I indication of surgical revascularization.METHODS AND RESULTS: A total of 147 consecutive patients who had a stenosis in the ostium and/or the midshaft of an unprotected left main coronary artery (treatment of the bifurcation not required) and were electively treated with percutaneous coronary intervention and sirolimus-eluting stents (n=107) or paclitaxel-eluting stents (n=40) in 5 centres were included in this registry. In 72 patients (almost 50%), intravascular ultrasound guidance was performed. Procedural success was achieved in 99% of the patients; in 1 patient with stenosis in the left main coronary artery ostium, a &gt;30% residual stenosis persisted at the end of the procedure, and the patient was referred for coronary artery bypass graft surgery. During hospitalization, no patients experienced a Q-wave myocardial infarction or died. One patient died 19 days after the procedure because of pulmonary infection. At long-term clinical follow-up (886+/-308 days), 5 patients had died; 7 patients had target vessel revascularization (5 repeat percutaneous coronary interventions and 2 coronary artery bypass graft surgeries), and of these only 1 patient had a target lesion revascularization. Angiographic follow-up was performed in 106 patients (72%) with a late loss of -0.01 mm. Restenosis in the left main trunk occurred only in 1 patient (0.9%).CONCLUSIONS: Percutaneous coronary intervention with sirolimus-eluting stents or paclitaxel-eluting stents implantation in nonbifurcation left main coronary artery lesions appears safe with a long-term major adverse clinical event rate of 7.4% and a restenosis rate of 0.9%

    Late and very late stent thrombosis following drug-eluting stent implantation in unprotected left main coronary artery: a multicentre registry

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    AIMS: To evaluate the occurrence of late and very late stent thrombosis (ST) following elective drug-eluting stent (DES) implantation in unprotected left main coronary artery (LMCA) stenosis in a large multicentre registry.METHODS AND RESULTS: All 731 consecutive patients who had sirolimus- or paclitaxel-eluting stent electively implanted in de novo lesions on unprotected LMCA in five centres were included. ST was defined according to Academic Research Consortium definitions. Four (0.5%) patients had a definite ST: three early (two acute and one subacute) and one late ST, no cases of very late definite ST were recorded. All patients survived from the event. Three patients had a probable ST. Therefore, 7/731 (0.95%) patients had a definite or a probable ST and all were on dual antiplatelet therapy at the time of the event. Possible (eight late and 12 very late) ST occurred in 20 (2.7%) patients. At 29.5 ± 13.7 months follow-up, a total of 45 (6.2%) patients had died; 31 (4.2%) of cardiac death. Ninety five (12.9%) patients had a target-vessel and 76 (10.4%) a target-lesion revascularization. Angiographic follow-up was performed in 548 patients (75%): restenosis occurred in 77 (14.1%) patients.CONCLUSION: Elective treatment of LMCA stenosis with DES appears safe with a 0.9% incidence of definite and probable ST at 29.5 ± 13.7 months.AIMS:To evaluate the occurrence of late and very late stent thrombosis (ST) following elective drug-eluting stent (DES) implantation in unprotected left main coronary artery (LMCA) stenosis in a large multicentre registry.METHODS AND RESULTS:All 731 consecutive patients who had sirolimus- or paclitaxel-eluting stent electively implanted in de novo lesions on unprotected LMCA in five centres were included. ST was defined according to Academic Research Consortium definitions. Four (0.5%) patients had a definite ST: three early (two acute and one subacute) and one late ST, no cases of very late definite ST were recorded. All patients survived from the event. Three patients had a probable ST. Therefore, 7/731 (0.95%) patients had a definite or a probable ST and all were on dual antiplatelet therapy at the time of the event. Possible (eight late and 12 very late) ST occurred in 20 (2.7%) patients. At 29.5 ± 13.7 months follow-up, a total of 45 (6.2%) patients had died; 31 (4.2%) of cardiac death. Ninety five (12.9%) patients had a target-vessel and 76 (10.4%) a target-lesion revascularization. Angiographic follow-up was performed in 548 patients (75%): restenosis occurred in 77 (14.1%) patients.CONCLUSION:Elective treatment of LMCA stenosis with DES appears safe with a 0.9% incidence of definite and probable ST at 29.5 ± 13.7 months

    Health consequences of using special diets with restricted carbohydrate consumption

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    Janowska Maria, Rogacka Karolina, Pyrak Bartłomiej, Kędziora–Kornatowska Kornelia. Health consequences of using special diets with restricted carbohydrate consumption. Journal of Education, Health and Sport. 2022;12(3):173-183. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.03.015 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.03.015 https://zenodo.org/record/6374571 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe:Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 01.03.2022. Revised: 16.03.2022. Accepted: 21.03.2022. Health consequences of using special diets with restricted carbohydrate consumption Maria Janowska1, ORCID: 0000-0003-0653-4428, [email protected] Karolina Rogacka2, ORCID: 0000-0001-9925-7305, [email protected] Bartłomiej Pyrak3, ORCID: 0000-0003-3489-2353, [email protected] Kornelia Kędziora–Kornatowska2, ORCID: 0000-0003-4777-5252, [email protected] 1 Department of Dietetic, Chair of Dietetic, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences-SGGW 2 Department of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Torun 3 Departament of Physical Pharmacy, Faculty of Pharmacy, Medical University of Warsaw ABSTRACT Introduction and purpose: There are many reasons why patients with specific health disorders, as well as people in good health, decide to follow special diets. Often their choice falls on dietary models that include limited carbohydrate intake. The most popular in this area are low-carbohydrate and high-protein diets, which have a significant impact on metabolism, making them of particular interest to people with excessive body weight. State of knowledge: Low-carbohydrate diets include many dietary models of varying restrictiveness, with or without achieving a state of ketosis. The ketogenic diet has the most promising clinical results in terms of effects on carbohydrate and fat metabolism. Long-term studies are still too few and inconsistent, also regarding the effects on weight loss compared to traditional approach. High-protein diets also include a reduction in carbohydrate intake, but with a higher proportion of protein in the total diet energy content. Observations on the effect of weight reduction and metabolic modification are inconsistent. The possible multi-directional negative health effects seem to be a strong argument against this approach and its recommendation. Conclusion: The basis of any reduction diet must be a reduced energy supply. This can be achieved in a variety of ways, which are designed to facilitate its implementation by patients, as well as to have the most beneficial effect on their impaired metabolism. Diversions from the traditional approach may have beneficial effects, but may also contribute to other health problems. It is important to consider the patients' health status as a whole, and to ensure specialist follow-up when using described special diets, because of possible side effects and difficulties in properly balancing the diet. They can only be recommended in specific cases, with a protein-rich diet appearing particularly dangerous. The standard in the management of excessive body weight remains the traditional approach, the effects of which are well documented and do not represent risk factors for other conditions. Key-words: special diets; low-carbohydrate diet; high-protein diet; weight los
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