1,721,403 research outputs found
Updating the journal sections for the evolution of research and clinical applications in artificial organs
No full textA special issue of our journal from the yESAO
No full textThe research community in the field of artificial organs is composed of senior scientist as well as of younger investigators, up to young scientists that recently entered in the field. The first artificial organs entered into the clinic more than 50 years ago already, and the field continued to attract biomedical engineers and medical doctors to combine their efforts and expertise for the advancement of these devices and for their clinical outcome
Mathematical description of transport of water and macromolecules through the glomerular capillary wall
No full textGlomerular diseases are associated with changes in glomerular membrane permeability properties that alter filtration rate of plasma water and barrier function of the capillary wall. To estimate intrinsic permeability properties that regulate transmembrane transport of water and macromolecules, theoretical analysis of renal clearance of tracer molecules can be used. The development, of adequate theoretical models is required to achieve. sufficient accuracy to simulate complicated biological processes. Current research in this area is aimed at improving and validating the presently available models in order to characterize the nature of permeability changes associated with pathological conditions. This is a key step in understanding the pathophysiological nature of glomerular diseases and in the development of effective treatments
Fluid dynamic implications on endothelial function
No full textThis paper reviews studies demonstrating the crucial role of shear forces induced by the motion of flow for physiological regulation of endothelial function and suggests how to identify areas prone to the development of vascular disease
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