237 research outputs found

    A TALE OF TWO CITIES: DIET, HEALTH AND MIGRATION IN POST-MEDIEVAL COVENTRY AND CHELSEA THROUGH BIOGRAPHICAL RECONSTRUCTION, OSTEOARCHAEOLOGY AND ISOTOPE BIOGEOCHEMISTRY

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    Biogeochemical research has over the past four-and-a-half decades improved our understanding of human interaction with past environments. The application of different isotope systems has allowed archaeologists to interpret ancient diet, migration and pollution. Although well established in archaeology, biogeochemical interpretations are burdened with questions not only as to the methodology employed but also whether the data presents a consistent picture of past human activity. The use of biographically identifiable individuals offers a means by which the isotope systems may be tested against extent documentary evidence. A sample of forty-five individuals, almost half of which were named individuals, were obtained from the sites of Holy Trinity (Coventry) and St. Luke's (Old Street, Chelsea) and the stable isotopes of carbon, nitrogen, oxygen, strontium and lead analysed. The biographies ofthe named individuals were reconstructed through analysis ofextant historical documentation and' used to provide a framework of interpretation for the biogeochemical teclmiques applied. Comparisons are made between the two sites in relation to the biogeochemical techniques employed, biographical reconstruction and osteoarchaeological evidence for disease, migration and diet to address methodological issues and broader questions on 'i,ndustrialisation' during the eighteenth and nineteenth centuries. The osteoarchaeological evidence suggests separation of the two groups into discrete' populations, one that is characterised by occupationally-derived osteoarthropathies (Coventry), and the second, Chelsea, which has an absence of these pathologies. This supports the historical character of the t\VO cities: Coventry as an industrial city in contrast to Chelsea, a 'village of palaces' or pleasure resort. Biogeochemically, carbon and nitrogen isotopes revealed a picture of status-based access to protein resources in a diet that is particularly dominated by freshwater fish, terrestrial omnivores such as pig, or a combination of the two. There is, however, little evidence for a difference in access to such resources between the sexes. Likewise, strontium and oxygen isotopes are capable of differentiating between the two populations and therefore in identifying local and migrant individuals, though limitations in the sample prevent the full utilisation of this data. In one case (Milborough Maxwell) the isotopic techniques \vere able to reveal trans-Atlantic migration between England and the Caribbean. Analysis of lead isotopes of the two populations indicates that while there is little to differentiate the two sites, heavy metal exposure is greater for the eighteenth and nineteenth centuries than for previous periods.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

    A politics of conversion: nihilism and love in Toni Morrison's fiction

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    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras.O estudo Uma Política de Conversão: Niilismo e Amor na Ficção de Toni Morrison começa com a idéia de que a Literatura Afro-Americana apresenta um sentido de auto-reflexividade e hibridismo, através do qual autobiografia dialoga com romance, o espiritual se funde com o político. A partir deste traço dialógico a auto-reflexividade é politicamente estabelecida entre niilismo e amor. Na política de conversão, o estudo analisa as formas como mulheres negras, individualmente ou em grupo, fogem da escravidão para a liberdade, avançam da individualidade para a coletividade, ou substituem niilismo por amor. Metodologicamente o estudo apresenta sete capítulos. O primeiro discute os aspectos dialógicos que ilustram as conexões entre narrativas espirituais, de escravos e ficção, entre espiritualidade e política. O segundo examina o diálogo entre a conversão, pregação pública e formação da comunidade em Diário e Experiências Religiosas de Lee. O capítulo sugere que ao afirmar espiritualidade e humanidade a narradora abre profundo espaço para a mulher negra reclamar direitos civis. O terceiro discute o diálogo no interior da política de conversão entre narrativa de escravos e ficção. Este diálogo lida com niilismo e amor em Incidentes de Jacobs e Amada, Sula e O Olho Mais Azul de Morrison. Para a análise de niilismo e amor valores individuais e coletivos são considerados em relação a cinco aspectos: ambiente e agente antagonistas, agente de apoio, propósito da personagem e resultado alcançado. É visível, no estudo, o apoio que certas mulheres recebem de suas comunidades para contra-atacar antagonistas. O apoio nem sempre resulta na superação do niilismo e, por isso, derrota temporária pode ocorrer antes que elas sejam reintegradas à comunidade, como acontece com Linda Brent. O quarto capítulo examina as fraquezas e as energias da política da conversão e a reintegração de Sethe Suggs à comunidade de Bluestone Road. O quinto avalia como a comunidade de Bottom tenta controlar a individualidade de Sula Peace e como um grupo de mulheres lideradas por Nel Wrights consegue resgatar o espírito de independência da heroína. O sexto mostra como a política da conversão das mulheres de Lorain é incapaz de garantir a saúde mental de Pecola Breedlove, mas consegue criar um papel mais consistente para o grupo. No sétimo, a conclusão examina da relação dialética entre niilismo e amor ou auto-amor nas experiências dos indivíduos e dos grupos. O estudo sugere que em Incidentes a busca de Linda Brent por liberdade envolve elementos de autodestruição e de autoempoderamento. Da mesma maneira, o estudo conclui que em Amada o amor que Sethe Suggs tem para as suas crianças mata a própria filha, enfatizando, assim, o desejo de livrá-la da escravidão. Igualmente em Sula, a individualidade de Sula Peace não apenas limita, mas também expande as experiências do grupo, levando-o à emancipação. Finalmente, em O Olho Mais Azul a luta de Pecola Breedlove por amor e beleza reflete auto-ódio ao mesmo tempo em que reconstrói a auto-apreciação de toda a comunidade

    Historic mills and cultural industries : a two-pronged approach to revitalization

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    This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: M.C.P., Massachusetts Institute of Technology, Department of Urban Studies and Planning, 2019Cataloged from student-submitted PDF version of thesis. Vita.Includes bibliographical references (pages 91-99).Decades past deindustrialization, former industrial centers across Massachusetts are committed to preserving and transforming historic mills. A variety of adaptive reuse projects spearheaded by cities and redevelopers alike have contribute anew to the area's diminished economy. Yet many mill towns and cities are still grappling with the question of how, exactly, to reanimate these massive buildings. At the same time, arts and culture-related strategies for economic development have continued to gain ground both locally and abroad. While artists have been known to gravitate towards deteriorating industrial building stock for its relative affordability and unique physical characteristics, planners and policy makers can also strategically support the development and sustainability of cultural facilities in historic mills as part of culture-led regeneration efforts. This thesis addresses the relationship between historic preservation and the cultivation of cultural industries. Drawing upon six case studies of arts and cultureƯfocused adaptive reuse in Lowell and Lawrence, Massachusetts, this study identifies the variety of challenges mill redevelopers face in creating cultural facilities and the range of strategies they deploy to achieve success. It also addresses the role of local government as a critical supporter of these types of projects, and derives lessons for city officials, developers, and other local stakeholders on how to advance the complementary goals of historic preservation, support of cultural industries, and economic and community revitaiization. This paper argues that the adaptive reuse of historic mills and cultural industry development are complementary strategies for economic and community revitalization that city officials should actively pursue by establishing plans, policies, and programs to facilitate the redevelopment of these industrial and historic landmarks.by Chelsea S. Bruck.M.C.P.M.C.P. Massachusetts Institute of Technology, Department of Urban Studies and Plannin

    Development of chemical tools for studying biological aldehydes: Enzyme substrates and fluorescent sensors

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    Because of their high reactivity, aldehydes are often recognized for their deleterious roles in the body, such as the generation of free radicals and contribution towards oxidative stress. However, these same aldehydes are also endogenously produced in the body and play vital biological roles under tightly controlled conditions. Because of this careful regulation, chemical tools for sensing aldehydes and their associated regulatory enzymes are necessary in order to learn more about their physiological roles and how their dysregulation may become pathological. In this work, we present the development of small molecule chemical tools to study aldehydes using a variety of approaches. First, we highlight our development of a fluorescent substrate for an aldehyde processing enzyme, aldehyde dehydrogenase 1A1 (ALDH1A1). ALDH1A1 belongs to a family of enzymes that process endogenous and exogenous aldehydes to carboxylic acids, detoxifying reactive aldehyde species and participating in complex signaling pathways, often related to stemness. To address the lack of isoform-selective ALDH1A1 probes, we designed a small molecule fluorescent substrate for ALDH1A1 that showed robust fluorescent turn-on only with this particular enzyme, which allowed us to use it as a tool to study the role of ALDH1A1 in cancer stem cells from a variety of cancer types, both in vitro and in vivo. Secondly, we highlight our development of a small molecule probe for formaldehyde that can detect this reactive aldehyde at endogenous levels. Our probe can detect formaldehyde in living cells and becomes highly fluorescent once concentrations become high enough to be pathological. We verified the utility of this probe in the HEK293T and Neuroscreen-1 cell lines, using both confocal microscopy and flow cytometry. In addition, we are currently developing a general small molecule aldehyde donor platform that is integrated with a fluorescent readout. The envisioned suite of tools will allow for spatiotemporal control of aldehyde release.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2022-05-01The student, Chelsea Anorma, accepted the attached license on 2020-05-06 at 16:18.The student, Chelsea Anorma, submitted this Dissertation for approval on 2020-05-06 at 16:26.This Dissertation was approved for publication on 2020-05-07 at 13:13.DSpace SAF Submission Ingestion Package generated from Vireo submission #15253 on 2020-08-25 at 17:29:56Made available in DSpace on 2020-08-26T23:58:41Z (GMT). No. of bitstreams: 3 ANORMA-DISSERTATION-2020.pdf: 8456863 bytes, checksum: 162230e465be71ff2c2b10b850374604 (MD5) LICENSE.txt: 4211 bytes, checksum: b4822721d40f2e59748ed5537579fe35 (MD5) PROQUEST_LICENSE.txt: 4557 bytes, checksum: 37570c318627f4ebc3f0176221d54786 (MD5) Previous issue date: 2020-05-07Embargo set by: Seth Robbins for item 115779 Lift date: 2022-08-26T23:58:55Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Onl

    Publi * CTC Sentinel

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    The CTC Sentinel is a monthly, independent publication that leverages the Center’s global network of scholars and practitioners to understand and confront contemporary threats posed by terrorism and other forms of political violence. May 2017 Contributing Author(s): John Horgan * Mia Bloom * Chelsea Daymon * Wojciech Kaczkowski * Hicham Tiflati Paul Cruickshank Franc Milburn Frank Straub * Jennifer Zeunik * Ben Gorban Michele Groppi April 2017 Contributing Author(s): ..

    Eyes wide open: Gender similarities and differences in sexual subjectivity and sexual objectification in today's hook-up culture

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    Abstract Sexual behavior among college students today is significantly different than in the past. Hooking-u

    The place of experimental tasks in geometry teaching: learning from the textbook designs of the early 20th century

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    The dual nature of geometry, in that it is a theoretical domain and an area of practical experience, presents mathematics teachers with opportunities and dilemmas. Opportunities exist to link theory with the everyday knowledge of pupils but the dilemmas are that learners very often find the dual nature of geometry a chasm that is very difficult to bridge. With research continuing to focus on understanding the nature of this problem, with a view to developing better pedagogical techniques, this paper examines the place of experimental tasks in the process of learning geometry. In particular, the paper provides some results from an analysis of innovative geometry textbooks designed in the early part of the 20th Century, a time when significant efforts were being made to improve the teaching and learning of geometry. The analysis suggests that experimental tasks have a vital role to play and that a potent tool for informing the design of such tasks, so that they build effectively on pupils’ geometrical intuition, is the notion of the geometrical eye, a term coined by Charles Godfrey in 1910 as “the power of seeing geometrical properties detach themselves from a figure"

    We are alive : (Mis)Reading Joy Harjo\u27s Noni Daylight as a Yellow Woman

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    This essay explores author Leslie Marmon Silko’s literary influence on poet Joy Harjo in order to rejuvenate the criticism surrounding Harjo’s poetic figure Noni Daylight. Featured in What Moon Drove Me To This? (1979) and She Had Some Horses (1983), existing scholarship defines Noni Daylight as Harjo’s alter ego. Prominent Harjo scholars cast Noni Daylight as a consistent figure whose trajectory can be linearly mapped between Harjo’s early books of poetry. However, the variations in time, space, age, and personality between each iteration of Noni Daylight suggest that she functions less as Harjo’s alter ego and more as a figure of survivance that celebrates womanhood\u27s pluralities in the vein of Silko’s Yellow Woman, a character inspired by the Laguna Pueblo oral tradition. The Yellow Woman both commends female sexual autonomy and emphasizes the necessity for women to conscientiously navigate language. With each appearance, the Yellow Woman lends a new perspective to narratives that women of native descent face in the wake of second wave feminism; similarly, each poem in which Noni Daylight features comments upon another facet of discovering female indigenous subjectivities within and beyond imposed national metanarratives of race, gender, and sexuality. Like the Yellow Women in Silko’s oeuvre, the Noni Daylights of Harjo’s poetry function as separate entities united under a common name to propose non-normative stories of womanhood
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