278 research outputs found
Oregon survey of clinic immunization practice changes due to the COVID-19 pandemic
No full textSteve Robison, Stefanie Murray, & Mimi Luther, Oregon Health Authority, Immunization Program.Title from PDF caption (viewed on January 4, 2021).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Tell Me: 30 Stories
No full textBy Mary Robison Counterpoint Press (Paperback, $14.00, ISBN: 1582432589, 10/2002) Thirty brief, sharply delineated short stories written over three decades by Robison (Days) chronicle emotional dislocation with witty dispassion. Robison’s characters, usually members of middle-class families, are often pictured grappling with the redefinition of roles, such as the teenaged star-gazing narrator of “An Amateur’s Guide to the Night” and her pill-popping single mother who pass for sisters and go on double-dates together. Or the newly idle Helen of “Independence Day,” recently returned to her father’s grand lakeside house in Ohio, who halfheartedly resists the pressure of her estranged husband, Terry, to get on with her life. Epiphanies are of less interest to Robison than rendering the shimmering immediacy of situation: “I could be getting married soon. The fellow is no Adonis,” establishes straightaway the art teacher of “In Jewel,” whose engagement means a way out of the dead-end eponymous miner town she’s always lived in. Robison locates her fairly comfortable characters anywhere from Beverly Hills (“Smoke”) to Ophelia, Ohio (“While Home”), to Washington, D.C. (“Smart”); they are waiting for rides in the rain or for babies to be born or for life, simply, to go on. And in every story her characters make valiant, hit-or-miss attempts to connect with one another. The brevity of these tales sometimes leaves the reader hanging, especially since their author delights in oblique details and non sequiturs. Yet nothing is superfluous, and in the spare sadness of Robison’s prose entire lives are presented. As the fiancée of “In Jewel” concludes, “All that I’ve ever owned or had is right out here for you to examine.” Copyright 2002 Reed Business Information, Inc. (from Publishers Weekly)https://egrove.olemiss.edu/mwp_books/1319/thumbnail.jp
What Ashland parents told us about religious exemptions
No full textprepared by: Steve Robison, Amanda Timmons, Lorraine Duncan, Jim Gaudino, Martha Priedeman, Hank Collins.Title from PDF cover (viewed on January 15, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
[Photograph 2012.201.B1098.0018]
No full textPhotograph used for a story in the Daily Oklahoman newspaper. Caption: "Mr. and Mrs. Reid Robison and Larry Nichols sample a Valentine dessert.
The EU dimension to the Scottish legal system
No full textThis chapter is concerned with the impact membership of the European Union has had upon the Scottish legal system. The chapter discusses the development of the original European Community from the original membership of 6 Member States through to its present membership of 28 in the expanded guise of the European Union. The chapter then discusses the sources of EU law before going on to outline the powers and roles of the various EU institutions. Finally, the chapter discusses the relationship between EU law and national law and the key role played by the Court of Justice of the European Union in this relationship
Procambarus liberorum Fitzpatrick 1978
No full textProcambarus liberorum Fitzpatrick, 1978: Osage Burrowing Crayfish General charateristics. Adults rarely exceed 90 mm in total length. The carapace has no cervical spines or tubercles, and the areola is closed. The rostrum has gently curving margins, lacks marginal spines, and the acumen is barely present. Chelae are blunt, heavy, and tubercles line the mesial margins of the palm and dactyl. In form I males, gonopods extend to the base of the third pereiopods, terminate in four processes, and have a strong rightangled shoulder at base of central projection. The central projection terminates distally and is directed slightly caudolaterally. In females, the annulus ventralis is deeply excavated in the cephalomedian half and has surrounding margins with spines or tubercles (Fitzpatrick, 1978). Life coloration. The background color is uniform and reddish brown (Figure 83). Ventral side is cream to white. There are no distinct coloration characteristics for this species. Similar species. In Oklahoma, P. liberorum closely resembles P. gracilis. It differs from P. gracilis by having gonopods having a wider caudal process, a base of the mesial process being straight, and by the cephalic process being directed less cephalically (Fitzpatrick, 1978). Distribution and habitat. Procambarus liberorum is a primary burrowing species that occurs near the eastern border of Oklahoma and throughout much of Arkansas (Robison & McAllister, 2006). According to our ecological niche model, regions with suitable environmental conditions are located within the Neosho River drainage, the western foothills of the Boston and Ouachita Mountains, and along the Red River in McCurtain and Choctaw counties (Figure 84). As a primary burrower, P. liberorum inhabits grasslands and areas that were formerly covered with native grasses, roadside ditches in these areas, and mountainous regions within the Boston and Ouachita Mountains (Robison & McAllister, 2006). It can often be found long distances from a permanent water source. Occasionally, this species can be found near creeks or wetland areas. Life history. Procambarus liberorum spends the majority of time within its burrow. Form I and II males as well as mature females have been collected by excavating burrowers in April and July (Robison & McAllister, 2006). It is likely that P. liberorum has a similar life history as P. gracilis. Syntopic species. Procambarus gracilis.Published as part of Morehouse, Reid L. & Tobler, Michael, 2013, Crayfishes (Decapoda: Cambaridae) of Oklahoma: identification, distributions, and natural history, pp. 101-157 in Zootaxa 3717 (2) on page 138, DOI: 10.11646/zootaxa.3717.2.1, http://zenodo.org/record/24853
A complementary understanding of residential energy demand, consumption and services
No full textThis chapter explores potential ways to implement, and benefits for policymaking of, the complementary use of two different types of modelling for analysing residential energy consumption and ethnographic research. The more traditional approach of techno-economic modelling is considered alongside agent-based modelling that incorporates both causal and intentional relationships; ethnographic approaches provide 'thick understanding' of the relationships between social and technical elements and the environment. In doing so, the chapter builds on real examples from academic-policy engagement in the EU on energy demand, consumption and services. We examine three myths of the role of modelling in policymaking and propose practical ways of employing different types of modelling in a complementary way to increase policymakers' understanding of residential energy demand, consumption and services. Finally, we make three concrete recommendations for developing future interdisciplinary work on integrating social and technical models for informing policy.Energy and Industr
Multiplexed immunoassay development for precision medicine diagnostics and protein characterization using silicon photonic microring resonators
No full textPrecision medicine offers the potential to transform healthcare by utilizing detailed biochemical insights into a patient’s disease state for therapeutic decision-making. Numerous disease specific biomarkers have emerged, but few are as dynamic and information-rich as those associated with the immune system. The immune system operates through a pathogen specific, biologically conserved response to coordinate detection and clearance. Immune cell associated signaling molecules, cytokines, modulate the immune response and their associated dynamics are ideal for monitoring host response. Profiling the immune response correlated to system perturbations provides a clinically valuable result for functional diagnostics.
Immunoassays are a powerful tool to quantitatively measure cytokine levels in biological solutions. While enzyme-linked immunosorbent assays have been the gold standard technique, multiplexed approaches have rapidly developed in response to the need for more complex biological signatures to precisely describe disease states. While many of these assays demonstrate robust intra-assay performance, variable inter-assay and multi-center performance is a consistent issue. Additionally, the inherent physiological fluctuations from patient-specific, but disease independent sources have largely hindered the clinical implementation of these assays.
This dissertation describes promising approaches to address the analytical and clinical challenges facing immune profiling guided precision medicine. Chapter 2 outlines the fundamental requirements for developing robust multiplexed immunoassays with silicon photonic microring resonator arrays. Using this basic protocol for assay development, Chapters 3 and 4 describe two distinct approaches toward diagnosing and monitoring infectious disease related states. Chapter 3 focuses on designing a functional diagnostic immunoassay for latent tuberculosis infection (LTBI) with the absolute assay output normalized by each subject’s basal immune response. Using this personalized normalization strategy, machine learning feature selection yielded promising results toward a diagnostic signature. Chapter 4 describes a multiplexed immune profiling approach incorporating rich temporal dynamics throughout the treatment of sepsis. The rapid immunoassay provides the cytokine trajectories of each subject throughout treatment, illustrating the dynamic changes accompanying immune challenge and subsequent therapeutic intervention. Chapter 5 leverages the near-real time monitoring capabilities of the platform to characterize the differential binding kinetics of monomeric and dimeric therapeutic antibodies as a means of structural characterization. Finally, Chapter 6 discusses the future of the LTBI diagnostic signature development, outlining a significant expansion of the biomarker panel, informatic analysis, and subject study enrollment.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2019-12-01The student, Heather Robison, accepted the attached license on 2017-11-29 at 10:02.The student, Heather Robison, submitted this Dissertation for approval on 2017-11-29 at 10:19.This Dissertation was approved for publication on 2017-11-29 at 15:09.DSpace SAF Submission Ingestion Package generated from Vireo submission #11777 on 2018-03-13 at 10:34:09Made available in DSpace on 2018-03-13T17:35:24Z (GMT). No. of bitstreams: 3
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Toward a Methodology for Evaluating DNA Variants in Nuclear Families
No full textThe genetic underpinnings of most pediatric-cancer cases are unknown. Population-based studies use large sample sizes but have accounted for only a small proportion of the estimated heritability of pediatric cancers. Pedigree-based studies are infeasible for most human populations. One alternative is to collect genetic data from a single nuclear family and use inheritance patterns within the family to filter candidate variants. This approach can be applied to common and rare variants, including those that are private to a given family or to an affected individual. We evaluated this approach using genetic data from three nuclear families with 5, 4, and 7 children, respectively. Only one child in each nuclear family had been diagnosed with cancer, and neither parent had been affected. Diagnoses for the affected children were benign low-grade astrocytoma, Wilms tumor (stage 2), and Burkitt’s lymphoma, respectively. We used whole-genome sequencing to profile normal cells from each family member and a linked-read technology for genomic phasing. For initial variant filtering, we used global minor allele frequencies, deleteriousness scores, and functional-impact annotations. Next, we used genetic variation in the unaffected siblings as a guide to filter the remaining variants. As a way to evaluate our ability to detect variant(s) that may be relevant to disease status, the corresponding author blinded the primary author to affected status; the primary author then assigned a risk score to each child. Based on this evidence, the primary author predicted which child had been affected in each family. The primary author’s prediction was correct for the child who had been diagnosed with a Wilms tumor; the child with Burkitt’s lymphoma had the second-highest risk score among the seven children in that family. This study demonstrates a methodology for filtering and evaluating candidate genomic variants and genes within nuclear families that may merit further exploration
Client Perjury and Legal Ethics : an Examination of the Defense Counsel's Dilemma
No full textv, 64 p.The author reviews the pros and cons of absolute client confidentiality from its initial discussion by Professor Monroe H. Freedman in 1966 to the controversial Model Rules of Professional Conduct proposed and debated by the American Bar Association in 1983. The author focuses specifically on the responsibilities of the attorney who knows that his client intends to commit perjury during a trial
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