1,720,975 research outputs found

    Funktionsprotektiver Verschluss einer urethrokutanen Fistel der prostatischen Harnröhre über einen perinealen Zugang mit Gracilis-Flap

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    Zusammenfassung Es wird von einem 36-jährigen Patienten berichtet, der beim Miktionieren Urin perianal aus einem kutanen Porus verliert. Nach entsprechender Diagnostik wird die Diagnose einer urethrokutanen Fistel aus der prostatischen Harnröhre unklarer Ätiologie gestellt. Aufgrund des jungen Alters und der sexuellen Aktivität, stellt die chirurgische Therapie eine Herausforderung dar. Über einen perinealen Zugang wird die Fistel isoliert und prostatanah ligiert, ohne die Gefäßnervenbündel zu gefährden. Um einen sicheren Fistelverschluss zu erzielen, wird anschließend ein Gracilis-Flap als Zwischenschicht zwischen Prostatahinterfläche und perkutanem Fistelausgang gelegt. Bis dato ist kein Fall einer erfolgreichen chirurgischen Therapie einer prostatokutanen Urinfistel beschrieben, die funktionserhaltend durchgeführt werden konnte

    Devastating course—good outcome! Excellent results thanks to artificial urinary sphincter implantation despite perineal urethrostomy—a case report

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    Zusammenfassung Dieser Fall beschreibt zum ersten Mal die Implantation eines AMS-800©-Sphinkters (Boston Scientific Corporation, Marlborough, MA, USA) bei einem Patienten mit Belastungsinkontinenz nach radikaler Prostatektomie, der durch komplizierten Verlauf der vorherigen Inkontinenztherapie letztlich mit einer perinealen Urethrostomie versorgt wurde. Die Kontinenzsituation und die postoperative Lebensqualität nach Versorgung mit dem neu implantierten Sphinktersystem zeigen, dass eine Boutonnière keine Kontraindikation für die Versorgung mittels künstlichem Blasenschließmuskel darstellt.Abstract In this case report, we describe, for the first time, the implantation of an AMS-800 sphincter (Boston Scientific Corporation, Marlborough, MA, USA) in a patient with stress incontinence following radical prostatectomy, who was ultimately treated with an perineal urethrostomy due to a complicated course of previous incontinence therapy. The continence status and postoperative quality of life after treatment with the newly implanted sphincter system clearly demonstrate that a boutonnière deformity is not a contraindication for treatment with an artificial urinary sphincter.Zusammenfassung Dieser Fall beschreibt zum ersten Mal die Implantation eines AMS-800©-Sphinkters (Boston Scientific Corporation, Marlborough, MA, USA) bei einem Patienten mit Belastungsinkontinenz nach radikaler Prostatektomie, der durch komplizierten Verlauf der vorherigen Inkontinenztherapie letztlich mit einer perinealen Urethrostomie versorgt wurde. Die Kontinenzsituation und die postoperative Lebensqualität nach Versorgung mit dem neu implantierten Sphinktersystem zeigen, dass eine Boutonnière keine Kontraindikation für die Versorgung mittels künstlichem Blasenschließmuskel darstellt.Abstract In this case report, we describe, for the first time, the implantation of an AMS-800 sphincter (Boston Scientific Corporation, Marlborough, MA, USA) in a patient with stress incontinence following radical prostatectomy, who was ultimately treated with an perineal urethrostomy due to a complicated course of previous incontinence therapy. The continence status and postoperative quality of life after treatment with the newly implanted sphincter system clearly demonstrate that a boutonnière deformity is not a contraindication for treatment with an artificial urinary sphincter

    Impact of multiparametric magnetic resonance imaging targeted biopsy on functional outcomes in patients following robot-assisted laparoscopic radical prostatectomy

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    Introduction Multiparametric magnetic resonance imaging guided prostate biopsy (mpMRI PBx) leads to a higher rate of successful nerve-sparing in robot-assisted laparoscopic prostatectomy (ns-RALP) for prostate cancer (PCa). This study aimed to evaluate the impact of mpMRI PBx compared to standard ultrasound-guided PBx on functional outcomes focusing on erectile function in patients following ns-RALP. Material and methods All RALPs performed between 01/2016 and 06/2021 were retrospectively stratified according to (attempted) ns vs. non ns RALPs and were then categorized based on the PBx technique (mpMRI PBx vs. standard PBx). We compared RALP outcomes such as pathological tumor stage, rates of secondary nerve resection (SNR) and positive surgical margin status (PSM). Furthermore, we explored the association between PBx-technique and patient-reported outcomes assessed 12 months after RALP using the prospectively collected 26-item Expanded Prostate Cancer Index Composite (EPIC-26) questionnaire. Chi-square tests and logistic regression analysis were conducted. Results A total of 849 RALPs included 517 (61%) procedures with (attempted) ns. Among these, 37.5% were diagnosed via preoperative mpMRI PBx. Patients with a preoperative standard PBx had a 57% higher association of PSM ( p  = 0.030) compared to patients with mpMRI PBx and a 24% higher risk of erectile dysfunction (ED) 12 months post RALP ( p  = 0.025). When ns was attempted, we observed a significantly higher rate of SNR in patients who underwent a standard PBx compared to those who received a mpMRI PBx (50.8% vs. 26.7%, p  < 0.001) prior RALP. In comparison, upgrading occurred more often in the standard PBx group (50% vs. 40% mpMRI PBx, p  = 0.008). Conclusion The combination of mpMRI PBx for PCa diagnosis followed by ns-RALP resulted in significantly fewer cases of SNR, better oncological outcomes and reduced incidence of ED 1 year after surgery. This included fewer PSM and a lower rate of postoperative tumor upgrading

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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