1,720,956 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
UHPLC-MS/MS analysis of selected drug candidates in biological materials
No full textUniverzita Karlova, Farmaceutická fakulta v Hradci Králové Katedra farmaceutické chemie a farmaceutické analýzy Kandidát: Lucie Švadlenková Konzultant: Mgr. Adam Reguli Vedoucí diplomové práce: doc. PharmDr. Petra Štěrbová, Ph.D. Název diplomové práce: UHPLC-MS/MS analýza vybraných potenciálních léčiv v biologickém materiálu Látky s kódovým označením JM-298 a JM-299 jsou polohové izomery, které jsou v současné době předmětem intenzivního výzkumu jako potenciální léčiva používaná v léčbě metabolických a jaterních onemocnění. Cílem této práce je vyvinout a validovat UHPLC-MS/MS metodu pro stanovení těchto analytů z plazmy a stanovit jejich farmakokinetický profil v tomto materiálu po podání myším. Při úpravě vzorku plazmy (25 l) bylo zkoušeno několik precipitačních činidel (acetonitril, okyselený acetonitril, methanol a okyselený methanol), kdy nejvyšší výtěžnosti a nejnižších matricových efektů bylo dosaženo při použití 250 l methanolu. Samotná analýza probíhala za využití UHPLC-MS/MS instrumentu s ionizací elektrosprejem v pozitivním módu. Separace probíhala na koloně Acquity UPLC BEH C18 (2,1×50 mm, 1,7 µm) opatřené předkolonou se stejným typem sorbentu. Kolonový prostor byl vyhříván na 30 řC a objem nástřiku vzorku byl 1 µl, průtoková rychlost mobilní fáze 0,3 ml/min. V rámci optimalizace byly...Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate: Lucie Švadlenková Supervisor - specialist: Mgr. Adam Reguli Supervisor: doc. PharmDr. Petra Štěrbová, Ph.D. Title of Thesis: HPLC-MS/MS analysis of selected drug candidates in biological materials Substances with codenames JM-298 and JM-299 are positional isomers that are currently under intensive research as potential drugs used in the treatment of metabolic and liver diseases. The aim of this work was to develop and validate the UHPLC-MS/MS method for the determination of these analytes from plasma and to determine their pharmacokinetic profile in this material after administration to mice. Several precipitating agents (acetonitrile, acidified acetonitrile, methanol and acidified methanol) were tested in plasma sample preparation (25l), where the highest recoveries and the lowest matrix effects were achieved when 250 l of methanol was used. The analysis was carried out using the UHPLC-MS/MS instrument with electrospray ionisation in positive mode. Separation was carried out using an Acquity UPLC BEH C18 (2.1×50 mm, 1.7 µm) protected with a pre-column with the same sorbent. The column oven was heated to 30 řC and the sample injection volume was 1 µl, the flow...Department of Pharmaceutical Chemistry and Pharmaceutical AnalysisKatedra farmaceutické chemie a farmaceutické analýzyFarmaceutická fakulta v Hradci KrálovéFaculty of Pharmacy in Hradec Králov
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Development of UHPLC-MS/MS method for analysis of selected drugs in a biological material
Get PDFCharles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate: Adam Reguli Supervisor - specialist: PharmDr. Hana Bavlovič Piskáčková, Ph.D. Supervisor: doc. PharmDr. Petra Štěrbová, Ph.D. Title of Thesis: Development of UHPLC-MS/MS method for analysis of selected drugs in a biological material Dexrazoxane is a cardioprotective drug clinically used against anthracycline induced cardiotoxicity. ICRF-193 was synthetized as a novel, more effective analogue of dexrazoxan. It was reported that inhibition of topoisomerase II, which seems to be crucial for cardioprotective effect, is mediated by an R,S diastereomer (ICRF-193) while the racemic mixture of R,R and S,S enantiomers is almost ineffective. Nevertheless our in vitro experiments with racemic mixture showed some cardioprotective effect. The aim of this work was 1) to examine the possible role of contamination of standard of racemic mixture with the ICRF-193 and 2) to develop solid phase extraction (SPE) for ICRF-193 and its metabolite (ICRF-193met) from plasma. The UHPLC coupled with a triple quadrupole mass spectrometer with electrospray ionization in positive mode. Bonus-RP column (100 × 3,0 mm, 1,8 μm) and formic acid (0,25%) with methanol as a mobile phase were used for..
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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