3,580 research outputs found

    Trans-Eyebrow Keyhole Approach

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    Nowadays, neurovascular diseases represent a field of enormous interest in clinical and surgical areas because of their complex management and recent advances about surgical and endovascular techniques. The difficult decision-making process at the base of these pathologies comprehends a wide series of treatment options which ought to be mastered by all the specialists facing the neurovascular pathology. This book addresses every aspect of the most common neurovascular diseases, as intracranial aneurysms, brain and spinal cord AVMs and cavernous angiomas, cranial and spinal dural arteriovenous fistulas, as well as spontaneous cerebral hemorrhages. It also focuses on the newer technologies regarding the intraoperative imaging of the cerebral blood flow. A large part is dedicated to the surgical approaches, but also tips and tricks of the management of these complex pathologies, presented by expert and world-renowned neurosurgeons, neuroradiologists and other specialists. The first section reviews the anatomy of the skull base, cranial and spinal cord vasculature. The second analyzes in detail the diagnosis, decision-making process, preoperative evaluation and surgical planning of the most common surgical neurovascular diseases. The third reports the most common surgical approaches employed for cranial neurovascular diseases, whereas the fourth miscellaneous section is mainly dedicated to the peculiar aspects regarding the management of giant and complex aneurysms, endovascular techniques, and also the role of radiosurgery for specific intra-axial vascular lesions. A further chapter describes the technical aspects regarding the use of indocyanine green and fluorescein videoangiography during neurovascular surgery. The main valuable strengths of this book lie in its case-based conception and wide number of colored figures, tables and treatment algorithms. In its structured organization, this book serves as a practical case-based guide for neurosurgeons, neurologists, neuroradiologists, residents, fellows, physicians and medical students involved in the field of neuroscience. The book enables all these specialists to gain high-value insights into the preoperative evaluation, planning, surgical techniques, pitfalls, prevention and management of complications of the surgical neurovascular pathology. Thanks to the contribution of different world-renowned neurosurgeons, neuroradiologists and experts, this book also promotes an updated overview of the most recent advances in neurovascular and neuroendovascular surgery, at the same time encouraging an interdisciplinary approach. (Imprint: Nova Medicine and Health

    Cerebral Bypass Surgery: Level of Evidence and Grade of Recommendation

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    BACKGROUND AND AIMS Cerebral bypasses are categorized according to function (flow augmentation or flow preservation) and to characteristics: direct, indirect or combined bypass, extra-to-intracranial or intra-to-intracranial bypass, and high-, moderate- or low-capacity bypass. We critically summarize the current state of evidence and grades of recommendation for cerebral bypass surgery. METHODS The current indications for cerebral bypass are discussed depending on the function of the bypass (flow preservation or augmentation) and analyzed according to level of evidence criteria. RESULTS Flow-preservation bypass plays an important role in managing complex intracranial aneurysms (level of evidence 4; grade of recommendation C). Flow-preservation bypass is currently only very rarely indicated in the treatment of cerebral tumors involving major cerebral arteries (level of evidence 5; grade of recommendation D). The trend has evolved in favor of partial resection and radiotherapy. To preserve the flow, the bypass is always a direct bypass.Flow-augmentation bypass is currently recommended for Moyamoya patients with ischemic symptoms and compromised hemodynamics (level of evidence 4; grade of recommendation C) and patients with hemorrhagic onset (level of evidence 1B; grade of recommendation A). Flow-augmentation bypass is currently not recommended for patients with recently symptomatic carotid artery occlusion, even in the setting of compromised cerebral hemodynamics (level of evidence 1A; grade of recommendation A), but may be considered in patients with hemodynamic failure and recurrent medically refractory symptoms as a final resort (level of evidence 5; grade of recommendation D). CONCLUSIONS The results of recent randomized clinical trials narrow the indication for cerebral bypass in the setting of ischemic cerebrovascular disease. However, cerebral bypass is still very useful for managing complex intracranial aneurysms (not amenable to selective clipping or endovascular therapies) and is the only treatment option for managing symptomatic patients with Moyamoya vasculopathy and impaired brain hemodynamics

    An assessment of the impact of possible CAP reform scenarios on Romanian agriculture

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    Using a simplified model, with key-variable the prices of two different possible scenarios of CAP reform after 2013 (moderate and radical), this paper present a comparison between the price effects of implementation of each reform scenario at 2015 horizon on Romanian agriculture. This short analysis shows that, under the presented hypotheses, the net welfare effect, due to the price changes, for the selected products, is positive in both reform scenarios, yet greater in the case of the radical reform. Integrated in the large context of Romanian development, it seems that the influence of CAP reform upon agriculture and rural areas will be most likely a gradual one: an interpenetration between the two scenarios is foreseeable, starting with the moderate reform that will dominate the period around 2013, the reform measures acquiring a more radical character afterwards.CAP reform, Romania, welfare effects, Agricultural and Food Policy,

    Role of Indocyanine Green Videoangiography in Identification of Donor and Recipient Arteries in Cerebral Bypass Surgery

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    The identification and preparation of a very good quality donor artery is a crucial step in every superficial temporal artery to middle cerebral artery (STA-MCA) bypass.For flow-preservation bypass performed for trapping of complex MCA aneurysms, the key element is the correct target of the recipient artery. When a cortical recipient artery (M4 segment of the MCA) is selected, this vessel must be a terminal branch of the artery whose sacrifice is necessary for definitive aneurysmal treatment.In this chapter we report on two techniques for (1) intraoperative mapping and preparation of good quality STA branch as the donor artery for STA-MCA bypass (mostly in the case the frontal branch of the STA needs to be used) and (2) selective identification of the correct superficial (M4 cortical) "recipient" artery in flow-preservation STA-MCA bypass performed for managing complex MCA aneurysms.Both techniques are based on the use of microscope-integrated indocyanine green videoangiography (ICG-VA), an intraoperative tool allowing observation and real-time assessment of blood flow in large and small vessels, with distinct evaluation of arterial, capillary, and venous phases.The two techniques contribute, respectively, to (1) reduce the risk of erroneous identification or injury of the donor artery in STA-MCA bypass procedures and (2) eliminate the risk of erroneous revascularization of a non-involved arterial territory in flow-preservation bypass surgery for managing complex MCA aneurysms

    Rich, Sturmian, and trapezoidal words

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    In this paper we explore various interconnections between rich words, Sturmian words, and trapezoidal words. Rich words, first introduced by the second and third authors together with J. Justin and S. Widmer, constitute a new class of finite and infinite words characterized by having the maximal number of palindromic factors. Every finite Sturmian word is rich, but not conversely. Trapezoidal words were first introduced by the first author in studying the behavior of the subword complexity of finite Sturmian words. Unfortunately this property does not characterize finite Sturmian words. In this note we show that the only trapezoidal palindromes are Sturmian. More generally we show that Sturmian palindromes can be characterized either in terms of their subword complexity (the trapezoidal property) or in terms of their palindromic complexity. We also obtain a similar characterization of rich palindromes in terms of a relation between palindromic complexity and subword complexity

    Characterization Results for the Poset Based Representation of Topological Relations - I: Introduction and Models

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    @article{DBLP:journals/informaticaSI/ForlizziN99, author = {Luca Forlizzi and Enrico Nardelli}, title = {Characterization Results for the Poset Based Representation of Topological Relations - I: Introduction and Models.}, journal = {Informatica (Slovenia)}, volume = {23}, number = {2}, year = {1999}, bibsource = {DBLP, http://dblp.uni-trier.de}

    Characterization Results for the Poset Based Representation of Topological Relations - II: Intersection and Union

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    @article{DBLP:journals/informaticaSI/ForlizziN00, author = {Luca Forlizzi and Enrico Nardelli}, title = {Characterization Results for the Poset Based Representation of Topological Relations - II: Intersection and Union.}, journal = {Informatica (Slovenia)}, volume = {24}, number = {1}, year = {2000}, bibsource = {DBLP, http://dblp.uni-trier.de}

    System-on-chip Computing and Interconnection Architectures for Telecommunications and Signal Processing

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    This dissertation proposes novel architectures and design techniques targeting SoC building blocks for telecommunications and signal processing applications. Hardware implementation of Low-Density Parity-Check decoders is approached at both the algorithmic and the architecture level. Low-Density Parity-Check codes are a promising coding scheme for future communication standards due to their outstanding error correction performance. This work proposes a methodology for analyzing effects of finite precision arithmetic on error correction performance and hardware complexity. The methodology is throughout employed for co-designing the decoder. First, a low-complexity check node based on the P-output decoding principle is designed and characterized on a CMOS standard-cells library. Results demonstrate implementation loss below 0.2 dB down to BER of 10^{-8} and a saving in complexity up to 59% with respect to other works in recent literature. High-throughput and low-latency issues are addressed with modified single-phase decoding schedules. A new "memory-aware" schedule is proposed requiring down to 20% of memory with respect to the traditional two-phase flooding decoding. Additionally, throughput is doubled and logic complexity reduced of 12%. These advantages are traded-off with error correction performance, thus making the solution attractive only for long codes, as those adopted in the DVB-S2 standard. The "layered decoding" principle is extended to those codes not specifically conceived for this technique. Proposed architectures exhibit complexity savings in the order of 40% for both area and power consumption figures, while implementation loss is smaller than 0.05 dB. Most modern communication standards employ Orthogonal Frequency Division Multiplexing as part of their physical layer. The core of OFDM is the Fast Fourier Transform and its inverse in charge of symbols (de)modulation. Requirements on throughput and energy efficiency call for FFT hardware implementation, while ubiquity of FFT suggests the design of parametric, re-configurable and re-usable IP hardware macrocells. In this context, this thesis describes an FFT/IFFT core compiler particularly suited for implementation of OFDM communication systems. The tool employs an accuracy-driven configuration engine which automatically profiles the internal arithmetic and generates a core with minimum operands bit-width and thus minimum circuit complexity. The engine performs a closed-loop optimization over three different internal arithmetic models (fixed-point, block floating-point and convergent block floating-point) using the numerical accuracy budget given by the user as a reference point. The flexibility and re-usability of the proposed macrocell are illustrated through several case studies which encompass all current state-of-the-art OFDM communications standards (WLAN, WMAN, xDSL, DVB-T/H, DAB and UWB). Implementations results are presented for two deep sub-micron standard-cells libraries (65 and 90 nm) and commercially available FPGA devices. Compared with other FFT core compilers, the proposed environment produces macrocells with lower circuit complexity and same system level performance (throughput, transform size and numerical accuracy). The final part of this dissertation focuses on the Network-on-Chip design paradigm whose goal is building scalable communication infrastructures connecting hundreds of core. A low-complexity link architecture for mesochronous on-chip communication is discussed. The link enables skew constraint looseness in the clock tree synthesis, frequency speed-up, power consumption reduction and faster back-end turnarounds. The proposed architecture reaches a maximum clock frequency of 1 GHz on 65 nm low-leakage CMOS standard-cells library. In a complex test case with a full-blown NoC infrastructure, the link overhead is only 3% of chip area and 0.5% of leakage power consumption. Finally, a new methodology, named metacoding, is proposed. Metacoding generates correct-by-construction technology independent RTL codebases for NoC building blocks. The RTL coding phase is abstracted and modeled with an Object Oriented framework, integrated within a commercial tool for IP packaging (Synopsys CoreTools suite). Compared with traditional coding styles based on pre-processor directives, metacoding produces 65% smaller codebases and reduces the configurations to verify up to three orders of magnitude

    Vision-Based Neurosurgical Guidance: Unsupervised Localization and Camera-Pose Prediction

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    Localizing oneself during endoscopic procedures can be problematic due to the lack of distinguishable textures and landmarks, as well as difficulties due to the endoscopic device such as a limited field of view and challenging lighting conditions. Expert knowledge shaped by years of experience is required for localization within the human body during endoscopic procedures. In this work, we present a deep learning method based on anatomy recognition, that constructs a surgical path in an unsupervised manner from surgical videos, modelling relative location and variations due to different viewing angles. At inference time, the model can map an unseen video’s frames on the path and estimate the viewing angle, aiming to provide guidance, for instance, to reach a particular destination. We test the method on a dataset consisting of surgical videos of transsphenoidal adenomectomies, as well as on a synthetic dataset. An online tool that lets researchers upload their surgical videos to obtain anatomy detections and the weights of the trained YOLOv7 model are available at: https://surgicalvision.bmic.ethz.ch
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