322,846 research outputs found
RANS-Based Aerothermal Database of LS89 Transonic Turbine Cascade Under Adiabatic and Cooled Wall Conditions
No full textModern gas turbines for aeroengines operate at ever-increasing inlet temperatures to maximize thermal efficiency, power, output and thrust, subjecting turbine blades to severe thermal and mechanical stresses. To ensure component durability, effective cooling strategies are indispensable, yet they strongly influence the underlying aerothermal behavior, particularly in transonic regimes where shock–boundary layer interactions are critical. In this work, a comprehensive Reynolds-Averaged Navier–Stokes (RANS) investigation is carried out on the LS89 transonic turbine cascade, considering both adiabatic and cooled wall conditions. Three operating cases, spanning progressively higher outlet Mach numbers (0.84, 0.875, and 1.020), are analyzed using multiple turbulence closures. To mitigate the well-known model dependence of RANS predictions, a model-averaging strategy is introduced, providing a more robust prediction framework and reducing the uncertainty associated with single-model results. A systematic mesh convergence study is also performed to ensure grid-independent solutions. The results show that while wall pressure and isentropic Mach number remain largely unaffected by wall cooling, viscous near-wall quantities and wake characteristics exhibit a pronounced sensitivity to the wall-to-recovery temperature ratio. To support further research and model benchmarking, the complete RANS database generated in this work is released as an open-source resource and made publicly
Diffusive author(s), cohesive author: Analysis of S/N (1994)
No full textThis study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A Simplified Approach to Geometric Non-Linearity in Clamped–Clamped Plates for Energy-Harvesting Applications
No full textEnergy-harvesting devices utilizing the Vortex-Induced Vibration (VIV) phenomenon are gaining significant research attention due to their potential to generate energy from small water flows, where conventional hydroelectric plants are impractical. Developing effective design methods for these systems is therefore essential. This study focuses on a critical configuration of such devices where energy extraction is achieved by harnessing the oscillatory deformation of two clamped–clamped plates, positioned downstream of the bluff body and subject to the effect of the vortex street. To simplify the preliminary design process, a semi-analytical approach, based on energetic considerations, is proposed to model the non-linear oscillations of the plates, eliminating the need for numerical simulations. The accuracy of this method is assessed through comparative analyses with finite element method (FEM) analyses, under both static and dynamic deformation conditions. The results validate the effectiveness of the proposed approach, offering insights into the effect of the adopted simplifications. In this framework, potential improvements to enhance the method’s reliability are identified. Thus, the work provides a practical model to address the preliminary design of these devices and suggests pathways for its further enhancement
Clinical Features and Rehabilitation Needs in Patients with Neuroinvasive West Nile Virus Infection: A Retrospective Analysis in an Area of High Incidence
No full textNeuroinvasive West Nile Virus disease (WNND) can cause lasting cognitive and motor impairments, impacting autonomy and quality of life. Given the scarcity of research on the rehabilitative needs of patients with WNV infection, this study aims to fill a critical gap by assessing the rehabilitation needs of a real-world cohort of WNND patients. We retrospectively analyzed WNND patients who received early Physical Medicine and Rehabilitation (PMR) evaluations during the 2022 outbreak in Veneto, Italy. Data included demographics, comorbidities, length of hospital stay, days at PMR evaluation, and rehabilitation duration until discharge or death, alongside objective examination findings and Barthel Index scores. Among 29 confirmed WNND patients, the median hospital stay was 20 days, with rehabilitation starting after a median of 7 days. Motor weakness affected 48.28% of patients, swallowing issues 6.90%, and respiratory issues 24.13%. A tailored rehabilitation protocol was designed for 96.55% of patients to address functional concerns and prevent complications. Barthel Index scores showed no significant change. Discharge settings were home (58.34%), other departments (25%), and rehabilitation facilities (16.67%). This study highlights the rehabilitation needs of WNND patients, particularly regarding neuromuscular deficits, swallowing, and respiratory issues, stressing the importance of a comprehensive rehabilitation strategy for improved outcomes
A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype
No full textPubMed ID: 23555276This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
A novel RUNX1 mutation with ANKRD26 dysregulation is related to thrombocytopenia in a sporadic form of myelodysplastic syndrome
No full textAging is associated with a higher risk of developing malignant diseases, including myelodysplastic syndromes, clonal disorders characterised by chronic cytopenias (anaemia, neutropenia and thrombocytopenia) and abnormal cellular maturation. Myelodysplastic syndromes arising in older subjects are influenced by combinations of acquired somatic genetic lesions driving evolution from clonal haematopoiesis to myelodysplastic syndromes and from myelodysplastic syndromes to acute leukaemia. A different pattern of mutations has been identified in a small subset of myelodysplastic syndromes arising in young patients with familial syndromes. In particular, dysregulation of ANKRD26, RUNX1 and ETV6 genes plays a role in familial thrombocytopenia with predisposition to myelodysplastic syndromes and acute leukaemia. Whether these genes affect thrombopoiesis in sporadic myelodysplastic syndrome with thrombocytopenia is still undefined. Thirty-one myelodysplastic syndromes subjects and 27 controls subjects were investigated. Genomic DNA was used for mutation screening (ETV6, RUNX1, 5′UTR ANKRD26 genes). Functional studies were performed in the MEG-01-akaryoblastic cell line. We found four novel variants of RUNX1 gene, all in elderly myelodysplastic syndromes subjects with thrombocytopenia. Functional studies of the variant p.Pro103Arg showed no changes in RUNX1 expression, but the variant was associated with deregulated high transcriptional activity of ANKRD26 in MEG-01 cells. RUNX1 variant p.Pro103Arg was also associated with increased viability and reduced apoptosis of MEG-01, as well as impaired platelet production. Our findings are consistent with dysregulation of ANKRD26 in RUNX1 haploinsufficiency. Lack of repression of ANKRD26 expression may contribute to thrombocytopenia of subjects with sporadic myelodysplastic syndromes
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No full textCan archives of audiovisual TV interviews be used to make authors more visible to students, and thereby reduce the learning gap between native and non-native language speakers in college classes? We examined students in a college course who learned about one scholar's ideas through watching an audiovisual TV interview (i.e., visible author format) and about another scholar's ideas through reading a formal text description (i.e., invisible author format). For the invisible author, native language speakers scored significantly higher than the non-native language speakers on a corresponding exam question (i.e., a cognitive measure), generated more words on the exam question (i.e., a motivational measure), and mentioned the author's name more often in answering the exam question (i.e., an affective measure). For the visible author, the groups did not differ on any of these measures. These findings provide evidence for the idea that making the author visible through audiovisual TV interviews can eliminate the learning gap between native and non-native language speakers. 3 Universities around the world serve students who are non-native speakers of th
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