115 research outputs found
Data for: Chemopreventive effects of vitamin D3 and its analogue, Paricalcitol, in combination with 5-Fluorouracil against colorectal cancer: The roles of calcium signalling molecules
No full textRaw data of animal studies including tumor characteristics, serum VD levels, tissue levels of Ca2+, oncogenes, tumor suppressor molecules and Ca2+-related molecules with the different therapie
Data for: Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat.
No full textVitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat
Data for: Enhanced remedial effects for vitamin D3 and Calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic molecules
No full textThe data contains the raw materials of the study titled: 'Enhanced remedial effects for vitamin D3 and Calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic molecules.&apos
Author response
No full textDetecting pathogens and mounting immune responses upon infection is crucial for animal health. However, these responses come at a high metabolic price (McKean and Lazzaro, 2011, Kominsky et al., 2010), and avoiding pathogens before infection may be advantageous. The bacterial endotoxins lipopolysaccharides (LPS) are important immune system infection cues (Abbas et al., 2014), but it remains unknown whether animals possess sensory mechanisms to detect them prior to infection. Here we show that Drosophila melanogaster display strong aversive responses to LPS and that gustatory neurons expressing Gr66a bitter receptors mediate avoidance of LPS in feeding and egg laying assays. We found the expression of the chemosensory cation channel dTRPA1 in these cells to be necessary and sufficient for LPS avoidance. Furthermore, LPS stimulates Drosophila neurons in a TRPA1-dependent manner and activates exogenous dTRPA1 channels in human cells. Our findings demonstrate that flies detect bacterial endotoxins via a gustatory pathway through TRPA1 activation as conserved molecular mechanism.sponsorship: Vlaams Instituut voor Biotechnologie Alessia Soldano Luis Franco Guangda Liu Natalia Mora Emre Yaksi Bassem A Hassanr Fonds Wetenschappelijk Onderzoek G.0702.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0077.15 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0680.10 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0681.10 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0503.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0654.15 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0761.10N Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0596.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0565.07 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar KU Leuven GOA/14/011 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar European Commission IUAP P7/13 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekensr KU Leuven OT/12/091 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar KU Leuven PF-TRPLe Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talavera (Vlaams Instituut voor Biotechnologie, Fonds Wetenschappelijk Onderzoek|G.0702.12, Fonds Wetenschappelijk Onderzoek|G.0077.15, Fonds Wetenschappelijk Onderzoek|G.0680.10, Fonds Wetenschappelijk Onderzoek|G.0681.10, Fonds Wetenschappelijk Onderzoek|G.0503.12, Fonds Wetenschappelijk Onderzoek|G.0654.15, Fonds Wetenschappelijk Onderzoek|G.0761.10N, Fonds Wetenschappelijk Onderzoek|G.0596.12, KU Leuven|GOA/14/011, KU Leuven|OT/12/091, European Commission|IUAP P7/13, KU Leuven PF-TRPLe)status: Publishe
DS_10.1369_0022155418782696 – Supplemental material for Acute and Chronic Iron Overloading Differentially Modulates the Expression of Cellular Iron-homeostatic Molecules in Normal Rat Kidney
No full textSupplemental material, DS_10.1369_0022155418782696 for Acute and Chronic Iron Overloading Differentially Modulates the Expression of Cellular Iron-homeostatic Molecules in Normal Rat Kidney by Bassem Refaat, Abdelghany Hassan Abdelghany, Mohammad A. BaSalamah, Mohamed El-Boshy, Jawwad Ahmad and Shakir Idris in Journal of Histochemistry & Cytochemistry</p
Les plages de Beyrouth : privatisation et communautarisation d’espaces publics
No full textBeirut beaches appeared on the western side of the city, which was once the most cosmopolitan district. The author describes these public spaces and the way of life prior to the war. He also considers the main evolutions that took place through the war period.El-Jisr Bassem. Les plages de Beyrouth : privatisation et communautarisation d’espaces publics. In: Reconstruire Beyrouth. Les paris sur le possible
Academic freedom at Palestinian universities : a human rights report
No full textBassem Eid traces the history of Palestinian Universities over three
periods - the Israeli occupation early 1970s until the Intifada, the
Intifada and its aftermath and the current era. The author examines
the serious problems and restrictions faced by University students
and intellectuals. He denounces a series of human rights violations
particularly the rights of freedom of expression and association. Such
violations include deportations, violence against students, arrests and
detentions without formal charges and unfair dismissal of professors
who spoke their minds. These human rights violations are not solely
a result of Israeli oppression but also a result of the interference of
the Palestinian Authority. The author probes into the University
Security Administration and the presence of undercover agents
within the universities, who monitor and report the activities of
individuals, are associated with the Islamic bloc or who criticise the
Palestinian Authority.peer-reviewe
Corrections to “D2D-V2X-SDN: Taxonomy and Architecture Towards 5G Mobile Communication”
No full textIn the above article [1], the following author bios must be updated as their posts and positions were upgraded, and the profile picture of Bassem F. Felemban was previously incorrect.Scopu
Aspects of the molecular biology of ectopic pregnancy : The role of activins and inducible nitric oxide synthase
No full textEThOS - Electronic Theses Online ServiceGBUnited Kingdo
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