20 research outputs found
Birth Stories of Trinidad and Tobago: Reena Teelucksingh-Ramsaroop
No full textReena Teelucksingh-Ramsaroop is a mother from Couva. She recalls when she first learned that she and her husband was expecting, how she was able to remain active throughout her pregnancy and her decision to seek pre-natal care from a doctor at the St. Augstine Private Hospital
Audit of Grade 3 Breast Cancer in New Zealand Women
No full textBreast cancer is the most common cancer in New Zealand women, accounting for approximately 3000 new registrations per year, affecting one in nine women and resulting in more than 600 deaths annually. The survival rate for breast cancer is dependent on multiple factors. These can include patient factors, tumour biology and resource-related factors such as access to health interventions.
This study analysed data of selected prognostic factors of grade 3 tumours over a 5-year period from 1st January 2011 to 31st December 2015 from four Breast Cancer Registries (Auckland, Waikato, Christchurch, and Wellington).
The study of 2667 women found that subjects in the older age group of >70 years were at increased risk of five-year mortality. Of the ethnicity groups, the Pacific Islander group were at increased risk, whereas the Māori group were at decreased risk. Histology type showed no statistically significant difference, whereas the molecular subtypes HER2 enriched and TNBC subjects were at increased risk. The study also showed that NZ Europeans presented the largest proportion of HER2 enriched and TNBC and the subjects from these two molecular subtypes were at increased risk of five-year mortality. In addition, analysis of the hormonal receptors showed that ER-negative, PR positive group were at increased risk and in contrast, the ER/PR positive group were at decreased risk. Subjects from stages II, IV and X were at increased risk, however, subjects from stage III were approaching significance.
From the analysis, it can be noted that the survival rates for Grade 3 breast cancer vary across the selected prognostic factors and therefore it can be summarised that the survival of this disease is dependent on multiple factors. These factors can include patient factors, tumour biology and resource-related such as access to health interventions.
Grade 3 is heterogeneous cancer and this study has shown that despite being high grade, not every patient has a poor outcome. Therefore, survival has to be combined with other factors such as biological and potentially socioeconomic factors associated with this disease.
The results of this study make an initial contribution to the understanding of high-grade malignancy. The selected prognostic factors were used primarily as a preliminary study into the overall survival of this disease. The inclusion of other prognostic factors would potentiate further studies into this aggressive cancer. Such studies should be supported in order to gain better understanding and establishment of measures for the prediction of survival with grade 3 breast cancer in New Zealand women
Audit of Grade 3 Breast Cancer in New Zealand Women
No full textBreast cancer is the most common cancer in New Zealand women, accounting for approximately 3000 new registrations per year, affecting one in nine women and resulting in more than 600 deaths annually. The survival rate for breast cancer is dependent on multiple factors. These can include patient factors, tumour biology and resource-related factors such as access to health interventions.
This study analysed data of selected prognostic factors of grade 3 tumours over a 5-year period from 1st January 2011 to 31st December 2015 from four Breast Cancer Registries (Auckland, Waikato, Christchurch, and Wellington).
The study of 2667 women found that subjects in the older age group of >70 years were at increased risk of five-year mortality. Of the ethnicity groups, the Pacific Islander group were at increased risk, whereas the Māori group were at decreased risk. Histology type showed no statistically significant difference, whereas the molecular subtypes HER2 enriched and TNBC subjects were at increased risk. The study also showed that NZ Europeans presented the largest proportion of HER2 enriched and TNBC and the subjects from these two molecular subtypes were at increased risk of five-year mortality. In addition, analysis of the hormonal receptors showed that ER-negative, PR positive group were at increased risk and in contrast, the ER/PR positive group were at decreased risk. Subjects from stages II, IV and X were at increased risk, however, subjects from stage III were approaching significance.
From the analysis, it can be noted that the survival rates for Grade 3 breast cancer vary across the selected prognostic factors and therefore it can be summarised that the survival of this disease is dependent on multiple factors. These factors can include patient factors, tumour biology and resource-related such as access to health interventions.
Grade 3 is heterogeneous cancer and this study has shown that despite being high grade, not every patient has a poor outcome. Therefore, survival has to be combined with other factors such as biological and potentially socioeconomic factors associated with this disease.
The results of this study make an initial contribution to the understanding of high-grade malignancy. The selected prognostic factors were used primarily as a preliminary study into the overall survival of this disease. The inclusion of other prognostic factors would potentiate further studies into this aggressive cancer. Such studies should be supported in order to gain better understanding and establishment of measures for the prediction of survival with grade 3 breast cancer in New Zealand women
Book review: history of the Church of the Nazarene in Trinidad and Tobago
No full textThe book is an account of the educational and spiritual endeavours of the Church of the
Nazarene during its 82 years of existence in Trinidad and Tobago. In the review of Gelien
Matthews’s book, I commented on the strengths of the publication. The author provides scholarly insight into the operation and organization of a vibrant Christian denomination. The study will certainly be of value to persons interested in the local history of Trinidad and Tobago.
Matthews’s lucid writing style will enable anyone to read and appreciate the mission of the Nazarene Church in Trinidad and Tobago. I have also focused on her use of sources. The footnotes and bibliography reveal diverse sources, such as journals, websites, interviews, and the Church’s manuals and monographs. The book’s seven chapters explore various aspects of the
Church of the Nazarene including its global mission, the role of the District Superintendent and the functioning of District Boards and Auxiliaries. The historical snapshots will provide the reader with an insight into both the contributions and challenges of the Nazarene Church
Biodiversity-based development in Small Island Developing States
No full textabstract: Small Island Developing States (SIDS) are quite diverse in terms of various development metrics, but are uniformly vulnerable both to macroeconomic shocks and to changes in the biodiversity that supports fisheries and tourism. This special section assembles a set of papers that analyze international demand for the natural resources associated with the two sectors, and the factors that lie behind changes in their supply. Since each stresses the resource base, albeit in different ways, we argue that limits on tourist pressure will be as important as limits on allowable fish catches in the future. We identify the challenge for SIDS as the need to implement an integrated, sustainable resource management strategy that allows biological resources to be allocated to their highest valued uses, while respecting the interests of those with prior rights to those resources.This is the authors' final manuscript as accepted. The final published version can be viewed at Environment and Development Economics / Volume 18 / Issue 04 / August 2013, pp 381-391 Copyright © Cambridge University Press 2013 DOI: http://dx.doi.org/10.1017/S1355770X13000260, Published online: 14 May 201
30,000 voices: Informing a better future for breast cancer in Aotearoa New Zealand
No full textIn the first and biggest study of its kind, our analysis of Te Rēhita Mate Ūtaetae - Breast Cancer Foundation National Register reveals New Zealand’s progress in tackling breast cancer.
By highlighting the areas where improvements are most needed, this report gives us a catalyst for change.
We’ve set out recommendations for decision-makers, medical professionals, and even ourselves to address the biggest challenges ahead of us.https://breastcancerregister.org.nz/images/assets/4744/1/breast%20cancer%20foundation%20national%20register%20report%202022%20final.pd
