43 research outputs found
A new species of the basal plesiadapiform Purgatorius (Mammalia, Primates) from the early Paleocene Ravenscrag Formation, Cypress Hills, southwest Saskatchewan, Canada: further taxonomic and dietary diversity in the earliest primates
Get PDFThe fossil record of the earliest primates, purgatoriid plesiadapiforms, has become increasingly well documented during the past two decades, but their dietary preferences remain poorly understood. While the available evidence, which consists mostly of isolated teeth and incomplete jaws with teeth, suggests that purgatoriids were insectivorous to omnivorous, we describe here a new species of Purgatorius, Purgatorius pinecreeensis sp. nov. , that extends the range of purgatoriid dental disparity toward greater omnivory than had been known before. P. pinecreeensis sp. nov. , from the early Paleocene (Puercan) Ravenscrag Formation of southwestern Saskatchewan, differs from other species of Purgatorius in having slightly lower crowned teeth with a lower trigonid relative to talonid, blunter and more swollen major cusps, more transverse lower molar paracristids, and m3 with a more robustly developed posterior lobe. Taken together, these specializations enhanced the capacity for crushing and grinding at the expense of orthal shear, and represent the first instance of a modest degree of bunodonty in the family. The discovery of P. pinecreeensis sp. nov. , along with other recently reported basal plesiadapiforms from the Puercan and Torrejonian of the northern Western Interior, lends additional support to the notion of a significant primate radiation soon after the Cretaceous–Paleogene extinction event.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
Geological setting of vertebrate microfossil localities across the Cretaceous-Paleogene boundary in southwestern Saskatchewan, Canada
No full textThe Frenchman and Ravenscrag formations of southwestern Saskatchewan, Canada, record an apparently continuous sequence of nonmarine clastic sediments across the Cretaceous-Paleogene (K-Pg) boundary. Extensive exposures of these fossil-rich sediments occur in the Frenchman River Valley, near the towns of Ravenscrag, Eastend, and Shaunavon, and have been a focus of study since the 1970s. Despite this long history of investigation, a comprehensive account of the geographic and stratigraphic positions of many of the significant fossil localities has yet to be published. Given this state of affairs, the goals of this paper are to 1) document the geographic locations, stratigraphic positions, and lithologies of eleven key vertebrate microfossil localities, including several new localities that have been recently discovered and 2) provide an update on the status of these fossil localities, the majority of which have not been sampled in the last 20 years. Four fossil localities are known from the lower Paleocene Ravenscrag Formation, all of which are Puercan in age: Rav W-1 (Pu2), French Fry (Pu1), Croc Pot (?Pu2), and Pine Cree (?Pu2). With the exception of Rav W-1, which has since been lost as a consequence of quarry reclamation, all of the Ravenscrag Formation localities remain accessible and continue to be productive. Seven vertebrate microfossil localities from the upper Maastrichtian Frenchman Formation are reported here, all of which are Lancian in age: Long Fall, Fr-1, By Gar Gap, Hairpin, Wounded Knee, Wounded C, and Gryde. With the exception of Long Fall and Wounded Knee, which have been lost through reclamation or construction, all of the Frenchman Formation localities are accessible and remain productive.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
Rhetorical gestures in British elocutionism
Get PDFThis project uncovers the rhetoric of gesture in British elocutionist handbooks on delivery (about 1650 to 1800). In the work of Bulwer, Sheridan, Walker, Priestley, Austin and others, the gesture exceeds its caricature in histories of rhetoric: an ancillary, if “detached” mechanism for the coercion of audience. Instead, the gesture produces meaning as it promotes appeal. It recommends presence as an inventional resource, and moving-with as a means to coming to terms, drawing toward what Crowley, writing in the context of contemporary political action, calls “civil discourse.” By tracking and analyzing the rhetorical gesture through interrelated thematic locations—medicine, theatre, pulpit, and philosophical chemistry—this project not only argues for reembodying invention, but also (like the Elocutionists themselves did) suggests that theorists of material and body rhetoric would benefit by extending their cross-disciplinary reach. Rhetorical gesture points out an alternative to “invention” (as well as rhetoric) that is by nature personal, oral and alphabetic. I offer this study/ gesture in support of current efforts to theorize the body’s role in the production of argument (Hawhee, Davis), as well as feminst rhetorics that assert the importance of looking beyond the speaker (Glenn, Ratcliffe) and even text, for rhetorical subjects and “stance.”Item withdrawn by Mark Zulauf ([email protected]) on 2012-08-27T14:24:44Z
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Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection
No full textRituximab, a monoclonal antibody which targets CD20 on B-cells, is now central to the treatment of a variety of malignant and autoimmune disorders. Despite this success a substantial proportion of B-cell lymphomas are unresponsive or develop resistance, hence more potent anti-CD20 mAb are continually being sought. Here we demonstrate that type II (tositumomab-like) anti-CD20 mAb are 5 times more potent than type I (rituximab-like) reagents in depleting human CD20 Tg B-cells, despite both operating exclusively via activatory FcR-expressing macrophages. Much of this disparity in performance is attributable to type I mAb-mediated internalization of CD20 by B-cells leading to reduced macrophage recruitment and the degradation of CD20:mAb complexes, shortening mAb half-life. Importantly, human B cells from healthy donors, and most cases of Chronic Lymphatic Leukemia (CLL) and Mantle Cell Lymphoma, showed rapid CD20 internalization which paralleled that seen in the Tg mouse B cells, while most Follicular Lymphoma (FL) and Diffuse Large B-Cell Lymphoma (DLBCL) cells were far more resistant to CD20 loss. We postulate that differences in CD20 modulation may play a central role in determining the relative efficacy of rituximab in treating these diseases and strengthen the case for focusing on type II anti-CD20 mAb in the clinic. <br/
State Library of Iowa Annual Report FY2010, July 1, 2009 to June 30, 2010
No full textAnnual report for State Library of Iow
Diversity in leadership: Australian women, past and present
Get PDFThis book provides a new understanding of the historical and contemporary aspects of Indigenous and non-Indigenous women’s leadership in a range of local, national and international contexts.
Overview
While leadership is an over-used term today, how it is defined for women and the contexts in which it emerges remains elusive. Moreover, women are exhorted to exercise leadership, but occupying leadership positions has its challenges. Issues of access, acceptable behaviour and the development of skills to be successful leaders are just some of them.
Diversity in Leadership: Australian women, past and present provides a new understanding of the historical and contemporary aspects of Indigenous and non-Indigenous women’s leadership in a range of local, national and international contexts. It brings interdisciplinary expertise to the topic from leading scholars in a range of fields and diverse backgrounds. The aims of the essays in the collection document the extent and diverse nature of women’s social and political leadership across various pursuits and endeavours within democratic political structures
Urbanizing the North-eastern Frontier: the frontier intelligentsia and the making of colonial Queenstown, c.1859-1857
No full textIncludes abstract.Includes bibliographical references.The rich and varied literature on the eastern Cape frontier has not yet reached the north-eastern frontier of the mid-nineteenth century. Urban centres and towns have also been largely ignored. Moreover, the perspective of the Anglophone intellectuals in these towns has rarely been analysed, and has instead been subsumed within a uniform ‘frontier voice’
Engaging the manuscript: new editions and reading the 'whole book' in Chetham's Library MS 8009
Get PDFThis thesis considers the intersection of the manuscript and its literature through an examination of the late fifteenth century manuscript, Chetham’s Library 8009 (Mun. A.6.31) and provides four diplomatic editions. This manuscript contains fourteen texts in Middle English including romance, hagiography, courtesy literature, and a comic text. This thesis argues for the importance of reading medieval literature in its manuscript context. Although there is a growing trend to consider the ‘whole book’ and integrate analysis of the material artefact with interpretation, much work remains to be done.
In Part I, this thesis presents a new paradigm for reading medieval literature, and argues that the manuscript forms a very literal community of texts, and that each text acts as a co-creator of meaning with the others. It then demonstrates four brief contextual readings that may be made within Chetham 8009 across generic boundaries, and that produce a shift in interpretive focus .
Part II provides four diplomatic editions from Chetham 8009: the Life of St Katherine, the Liber Catonis, John Russell’s Book of Carving and Nurture, and the Book of the Duke and Emperor.
This thesis aims to contribute to the study of medieval literature by arguing for a methodological shift in the way the literature is approached and by providing access to four texts either previously unedited or not easily accessible
Cadaveric Renal transplantation with Cyclosporine: Experiences in 148 patients at a single institution.
Get PDFSupplement to physical exchanges at the air-sea interface: UK-SOLAS Field Measurements
Get PDFAuthor Posting. © American Meteorological Society, 2009. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Bulletin of the American Meteorological Society 90 (2009): ES9-ES16, doi:10.1175/2008BAMS2578.2
