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Functional and structural correlates of persistent ST elevation after acute myocardial infarction successfully treated by percutaneous coronary intervention
Functional and structural correlates of persistent ST elevation after acute myocardial infarction successfully treated by percutaneous coronary intervention.
Galiuto L, Barchetta S, Paladini S, Lanza G, Rebuzzi AG, Marzilli M, Crea F.
Source
Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy. [email protected]
Abstract
BACKGROUND:
In the thrombolytic era, persistence of ST-segment elevation was considered a marker of left ventricular (LV) aneurysm. ST-segment elevation may still be found persistently raised after successful primary percutaneous coronary intervention (PCI). Echocardiographic correlates of this finding, however, are still poorly known.
METHODS AND RESULTS:
82 consecutive patients with first ST-segment elevation myocardial infarction and successful PCI were divided into patients with persistent ST-segment elevation at discharge (sum of ST >4 mm) (n = 33) and those without persistent ST-segment elevation (n = 49). Conventional and myocardial contrast echocardiography were performed at discharge and at 6 months. At discharge, LV aneurysm was more common in patients with persistent ST elevation (27% vs 8%, p<0.005). Similarly, the wall motion score index was higher (2.5 vs 2.0, p<0.005) and microvascular damage larger (2.3 vs 1.8, p<0.005) in patients with persistent ST-segment elevation. At 6 months' follow-up, LV volumes were similar in the two groups.
CONCLUSIONS:
After primary PCI, persistent ST-segment elevation is associated with LV aneurysm formation in 30% of cases, it is not associated with significantly larger LV dilatation but with larger microvascular damage and dysfunctioning risk area
Distal radius articular fractures: a comparison between ORIF with angular stability plate and percutaneous Kirschner wires.
Distal radius articular fractures: a comparison between ORIF with angular stability plate and percutaneous Kirschner wires.
Tronci V1, Campochiaro G, Gazzotti G, Rebuzzi M, Tsatsis C, Catani F.
Author information
Abstract
PURPOSE OF THE STUDY:
To analize and compare vantages and disadvantages in long-term of two different techniques to treat distal radius articular fractures: ORIF with plate versus percutaneous pinning with K-wires.
MATERIALS AND METHODS:
We reviewed 77 distal radial articular fractures treated surgically from 2005 to 2009. Fractures were divided in two homogeneous groups according to patient age, gender, fracture-type and follow-up. The first group was treated with ORIF using angular stability volar plate, while the second one with closed reduction, K-wires percutaneous pinning and ante-brachial plaster casting. Functional outcomes were assessed with MAYO and DASH score, wrist range-of-movement and handgrip. Radiographic parameters were calculated in the post-operative and long-term x-rays.
RESULTS:
ORIF group showed better mean DASH and MAYO score, range of movement and handgrip strength compare to K-wires group. Expecially in type C fractures and in younger patients (<65 years). Minor differences were observed in type B fractures. About complications: two cases of surgically-treated medial nerve compression in ORIF group and one in K-wire group, one case of algodystrophy in K-wire group. Referring to radiographic parameters, long term values show data positive for ORIF.
CONCLUSIONS:
Though several studies about these techniques has been performed, but no scientific evidence proves the superiority of one surgical treatment. C-type need to be treated with plate in young patients or in elderly patients with high functional demand. Elderly patients with low functional demand can achieve satisfactory results also with percutaneous pinning, especially in Btype fractures
Anti-angiogenesis boosts chemo-immunotherapy in patients with EGFR mutations or baseline liver metastases: Insights from IMpower150 study
Temporal changes of microvascular obstruction after acute reperfused myocardial infarctio
Advances in the prediction of long-term effectiveness of immune checkpoint blockers for non-small-cell lung cancer
Longitudinal, Transmural and Intramyocardial Quantitation of Post-Infarct Microvascular Damage Using a Novel Myocardial Contrast Echocardiographic Technology
Assessment of bone defects in anterior shoulder instability
Glenohumeral bone defects are a common finding in shoulder instability and they are strongly correlated with recurrence of dislocation and failure following arthroscopic Bankart repair. Most authors agree that open surgery should be considered in the presence of certain conditions: glenoid bone loss > 25%, a lesion involving > 30% of the humeral head, an engaging Hill-Sachs lesion, bipolar bone lesions even without engagement.
A careful imaging evaluation must therefore be performed in order to identify, quantify and characterize the bone defects. Even though magnetic resonance has important additional value in the assessment of the glenoid labrum and rotator cuff, computed tomography scan is the examination of choice for studying bone defects.
Several methods have been proposed to quantify the extent of the glenoid bone defect; the most accurate ones utilize two-dimensional computed tomography images with multiplanar reconstructions (PICO method) or more sophisticated three-dimensional reconstruction software. Conversely, the literature lacks studies that accurately quantify humeral bone defects and, above all, that demonstrate definitively the clinical and prognostic significance of the lesion location and size
Infarct Related Artery Flow Reserve After Primary Coronary Intervention is Significantly Impaired, Independently from the Extent of Microvascular Damage
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