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    Corneal topography and the morphology of the palpebral fissure

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    The notion that forces from the eyelids can alter the shape of the cornea has been proposed for many years. In recent times, there has been a marked improvement in our ability to measure and define the corneal shape, allowing subtle changes in the cornea to be measured. These improvements have led to the findings that pressure from the eyelids can cause alterations in corneal shape following everyday visual tasks such as reading. There are also theories to suggest that pressure from the eyelids may be involved in the aetiology of corneal astigmatism. In this program of research, a series of experiments were undertaken to investigate the influence of the eyelids on the shape of the cornea.\ud \ud In the first experiment, an investigation into the diurnal variation of corneal shape was carried out by measuring corneal topography at three different times (approximately 9 am, 1 pm and 5 pm) during the day over three days of the week (Monday, Tuesday and Friday). Highly significant diurnal changes were found to occur in the corneal topography of 15 of the 17 subjects. This change typically consisted of horizontal bands of distortion in the superior, and to a lesser extent, inferior cornea, increasing throughout the day (and returning to baseline the next morning). These changes appeared to be related to forces from the eyelids on the anterior cornea. Some changes were also found in corneal astigmatism. Corneal astigmatism power vector J0 (astigmatism 90/180°) was found to increase slightly over the course of the week. Whilst the changes in astigmatism were small in magnitude, this result leaves open the possibility that pressure from the eyelid may cause changes in corneal astigmatism. If pressure from the eyelids is involved in the aetiology of corneal astigmatism, then one may expect associations to exist between certain characteristics of the eyelids and corneal shape. An experiment was then undertaken to explore these possible associations.\ud \ud We defined the average morphology of the palpebral fissure in different angles of vertical gaze for 100 young normal subjects. This was achieved through analysis of digital images that were captured in primary gaze, 20° downgaze and 40° downgaze. Parameters defining the size, position, angle and contour of the eyelids were determined. Highly significant changes were found to occur in the palpebral fissure with downward gaze. The palpebral aperture narrows in downward gaze, and the angle of the eyelids changes from being slightly upward slanted in primary gaze, to being slightly downward slanted in downward gaze. The eyelid margin contour also flattens significantly in downward gaze.\ud \ud The average topography of the central and peripheral cornea was also defined for this same population. A technique was used that allowed the capture and subsequent combination of topography data from both the central and the peripheral cornea. The use of this technique provided a large corneal topography map, with data extending close to the limbus for each subject. Marked flattening was found to occur in the peripheral cornea and a conic section was found to be a poor descriptor of corneal contour in the periphery (i.e. greater than 6 mm diameter). Corneal astigmatism was also found on average to reduce in the periphery. However a number of distinct patterns of peripheral corneal astigmatism were noted in the population. Corneal astigmatism in the peripheral cornea was either found to remain stable (59% of subjects), increase (10% of subjects) or reduce (31% of subjects) in magnitude in comparison to the amount of central corneal astigmatism.\ud \ud We also investigated associations between the parameters defining the palpebral fissure and parameters describing corneal shape in this population of subjects. A number of highly significant associations were found between the morphology of the palpebral fissure in primary gaze and the shape of the cornea. A general tendency was found for subjects with wider horizontal palpebral fissure widths to exhibit larger corneas and also flatter central corneal powers. There were also highly significant associations found between the angle of the eyelids and the axis of corneal astigmatism, but not the magnitude of corneal astigmatism. The associations found between corneal astigmatism and palpebral fissure morphology is further evidence supporting the hypothesis that pressure from the eyelids is involved in the aetiology of corneal astigmatism.\ud \ud The results of these investigations have shown that corneal changes as a result of eyelid forces occur in the majority of young subjects tested over the course of a normal working day. The average morphology of the palpebral fissure and topography of the central and peripheral cornea has also been defined in detail for a large population of young subjects. Significant associations were found between corneal astigmatism and the morphology of the palpebral fissure. Whilst these results support a model of corneal astigmatism development based on eyelid morphology, they do not prove causation. Further research including measurement of eyelid pressure and corneal rigidity may aid in understanding the exact aetiology of the magnitude and axis of corneal astigmatism

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Author Under Sail The Imagination of Jack London, 1893-1902

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    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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