1,721,574 research outputs found
An ALE Interpolation-Free Strategy for Unsteady Flow Simulations Using Finite Volume and Residual Distribution Schemes over Adaptive Grids
No full textFabNet: An automatic hyperledger fabric network wizard
Full text linkHyperledger Fabric is continually evolving technology, thanks to its active community providing new features and functionalities. However, it still lacks a user-friendly interface that makes its adoption immediate and straightforward. In particular, one of the main barriers for non-expert users is the comprehension and creation of a network. In this paper, we present FabNet, a user-friendly wizard reducing the effort for the configuration and deployment of the Fabric blockchain network
Investigation of undergraduate and master students’ understanding of gene structure and function
No full textThe concept of gene is constantly changing, becoming increasingly complex and difficult to teach and learn. This study investigates the gene concept acquired by Italian undergraduate and master students in biological/natural sciences. The undergraduate students attended a basic biology course the year before the survey, while the master students attended a general genetics course two years before. Students were asked to answer the open-ended question 'what is a gene?' Answers were analysed in terms of gene concept (structure and function) and gene-trait relationship. The survey was repeated for five academic years to check if the results fluctuated over time. A significant difference was found between the two groups of students with regard to the gene concept: a simplistic Mendelian conception was prevalent among the undergraduates, whereas a more complex modern/molecular conception prevailed among the master students. Surprisingly, there was no significant difference in the gene-trait relationship: most students in both groups described it in a reductionist way (a single gene determines a trait). These results suggest that there is a need to improve the teaching of biology and genetics, to prevent students from losing sight of the complexity and to avoid oversimplification, which could lead to a deterministic view
An adaptive ALE scheme for non-ideal compressible fluid dynamics over dynamic unstructured meshes
Full text linkThis paper investigates the application of mesh adaptation techniques in the non-ideal compressible fluid dynamic (NICFD) regime, a region near the vapor–liquid saturation curve where the flow behavior significantly departs from the ideal gas model, as indicated by a value of the fundamental derivative of gasdynamics less than one. A recent interpolation-free finite-volume adaptive scheme is exploited to modify the grid connectivity in a conservative way, and the governing equations for compressible inviscid flows are solved within the arbitrary Lagrangian–Eulerian framework by including special fictitious fluxes representing volume modifications due to mesh adaptation. The absence of interpolation of the solution to the new grid prevents spurious oscillations that may make the solution of the flow field in the NICFD regime more difficult and less robust. Non-ideal gas effects are taken into account by adopting the polytropic Peng–Robinson thermodynamic model. The numerical results focus on the problem of a piston moving in a tube filled with siloxane (Formula presented.), a simple configuration which can be the core of experimental research activities aiming at investigating the thermodynamic behavior of NICFD flows. Several numerical tests involving different piston movements and initial states in 2D and 3D assess the capability of the proposed adaption technique to correctly capture compression and expansion waves, as well as the generation and propagation of shock waves, in the NICFD and in the non-classical regime
Epigenetic dysregulation in various types of cells exposed to extremely low-frequency magnetic fields
Full text linkEpigenetic mechanisms regulate gene expression, without changing the DNA sequence, and establish cell-type-specific temporal and spatial expression patterns. Alterations of epigenetic marks have been observed in several pathological conditions, including cancer and neurological disorders. Emerging evidence indicates that a variety of environmental factors may cause epigenetic alterations and eventually influence disease risks. Humans are increasingly exposed to extremely low-frequency magnetic fields (ELF-MFs), which in 2002 were classified as possible carcinogens by the International Agency for Research on Cancer. This review summarizes the current knowledge of the link between the exposure to ELF-MFs and epigenetic alterations in various cell types. In spite of the limited number of publications, available evidence indicates that ELF-MF exposure can be associated with epigenetic changes, including DNA methylation, modifications of histones and microRNA expression. Further research is needed to investigate the molecular mechanisms underlying the observed phenomena
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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