2,653 research outputs found
Investigation of the interaction phenomena between foot and insole by means of a numerical approach
No full textThe biomechanical response of foot with regard to interaction phenomena occurring at interface with insole inserted in
the shoe is investigated by using a numerical approach. At this purpose, a complex three-dimensional model of the foot
is defined from biomedical images, while insole conformation is acquired by laser scanner technique, leading to the finite
element discretization. Foot tissues are characterized by means of specific constitutive visco-hyperelastic anisotropic formulations,
recalling previous research activity. The mechanical behavior of insole material is analyzed by means of experimental
compression tests that highlight the geometric and material non-linear response, represented by a hyperelastic
formulation, while a hyperfoam formulation is assumed for the sole. Numerical analysis considers the mid-stance phase
of the gait and allows to interpret the response of overall foot, insole and sole system. The investigation represents a
preliminary step of a parametric analysis addressed to support footwear design considering different configurations of
components. As matter of example, the influence of variation in insole material properties is reported
A singular case of cavernous internal carotid artery aneurysm in patient with cavernous sinus syndrome and bacterial meningitis
No full textAbstractWe report the uncommon case of an acute cavernous sinus syndrome in a patient who was consequently discovered to have both a cavernous internal carotid artery aneurysm and bacterial meningitis. Which came first, the chicken or the egg? Which of the two, the aneurysm or the meningitis, gave rise to the patient’s symptoms? We briefly reviewed the literature of similar cases and tried to analyze the possible pathophysiological relationship between these findings. Moreover, this case highlights the importance of a multidisciplinary management of these patients to better decide between a medical and a surgical and/or endovascular treatment
Discorso pedagogico e prospettiva sistemico-relazionale
No full textStarting with a few thoughts about the current pedagogical debate expressed within the work, the contribution of Luigi Pati, highlights the importance of relational systems perspective in the pedagogical discourse. The author proposes an analysis and historical evolution of the General Theory of Systems (TGS), illustrating the importance of the same in the action and in the educational relationship between educator and student
Sobre Luigi Ferrajoli y el constitucionalismo
No full textIn this paper, the author poses several general questions on Luigi Ferrajoli’s paper. Firstly, he writes on Ferrajoli’s construction of a theory that comprehensively infers, still always in a deductive way, the scope of a complex set of primitive terms and definitions. Secondly, the author questions his way to understand and particularly to reconstruct the so-called «constitutional paradigm». Thirdly, the author writes about Ferrajoli’s approach to the concepts of «validity» and «enforcement» of rules. Fourthly, he discusses Ferrajoli’s definition of garantist constitutionalism, particularly his conception of this sort of constitutionalism as an improvement or complement to legal positivism -inasmuch as constitutionalism respects both the being of the Law and its normative or ideal (must be) dimension. Finally, he revises the objections that Ferrajoli addressed to constitutionalism (the thesis of the separation between Law and morality, the distinction between principles and rules and the criticism of the weighting) introducing new arguments.El autor plantea una serie de objeciones al texto de Luigi Ferrajoli. En primer lugar, se refiere a la construcción por parte de Ferrajoli de una teoría que infiere de un modo exhaustivo, pero siempre deductivamente, el alcance de un complejo conjunto de términos primitivos y definiciones. En segundo lugar, el autor duda sobre la forma de ver y, sobre todo, de reconstruir el llamado «paradigma constitucional». En tercer lugar, el autor objeta el tratamiento que Ferrajoli hace de los conceptos de «validez» y «vigor» de las normas. En cuarto lugar, hace referencia a la definición que Ferrajoli realiza del constitucionalismo garantista, en concreto a la consideración de éste como mejora o complemento del positivismo jurídico que se logra gracias a que el constitucionalismo observa no sólo el «ser» sino el «deber ser» del Derecho. Finalmente, repasa las críticas que Ferrajoli realiza al constitucionalismo (la tesis de la separación entre Derecho y moral, la distinción entre principios y reglas y la crítica a la ponderación), expresando sus diferencias
Which Are the Best Regimens of Broad-Spectrum Beta-Lactam Antibiotics in Burn Patients? A Systematic Review of Evidence from Pharmacology Studies
No full textBackground: Burn injury causes profound pathophysiological changes in the pharmacokinetic/pharmacodynamic (PK/PD) properties of antibiotics. Infections are among the principal complications after burn injuries, and broad-spectrum beta-lactams are the cornerstone of treatment. The aim of this study was to review the evidence for the best regimens of these antibiotics in the burn patient population. Methods: We performed a systematic review of evidence available on MEDLINE (from its inception to 2023) of pharmacology studies that focused on the use of 13 broad-spectrum beta-lactams in burn patients. We extracted and synthetized data on drug regimens and their ability to attain adequate PK/PD targets. Results: We selected 35 studies for analysis. Overall, studies showed that both high doses and the continuous infusion (CI) of broad-spectrum beta-lactams were needed to achieve internationally-recognized PK/PD targets, ideally with therapeutic drug monitoring guidance. The most extensive evidence concerned meropenem, but similar conclusions could be drawn about piperacillin-tazobactam, ceftazidime, cefepime, imipenem-clinastatin and aztreonam. Insufficient data were available about new beta-lactam-beta-lactamase inhibitor combinations, ceftaroline, ceftobiprole and cefiderocol. Conclusions: Both high doses and CI of broad-spectrum beta-lactams are needed when treating burn patients due to the peculiar changes in the PK/PD of antibiotics in this population. Further studies are needed, particularly about newer antibiotics
Six Characters in Search of an Author (Text)
No full textSix Characters in Search of an Author (Sei personaggi in cerca d’autore) is an Italian three-act play written by Luigi Pirandello in 1921, considered as one of the earliest examples of absurdist theatre. It’s a play within a play that deals with perceptions of reality and illusion, and plays with the ideas of identity and relative truths
Luigi Pirandello: In Search of an Author
No full textIn 1925 Luigi Pirandello brought his troupe to England as part of a worldwide tour. This classic program re-creates one day in London as "The Einstein of the Theater" watches his plays and, away from the footlights, confronts the paradoxical nature of his life. Portions of Six Characters in Search of an Author; Henry IV; Right You Are, If You Think You Are; and The Rules of the Game are meticulously staged, using actors' accounts, period descriptions, and Pirandello's own comments. Plus, biographical notes written by Pirandello himself provide a new angle on the inner torment that animates his work, while playwright Julian Mitchell and novelist Leonardo Sciascia critically analyze the action as it unfolds. (60 minutes, color
Organizing Chamber Music as Culture
No full textIn this paper Luigi Maria Sicca suggests on the one hand that organization theory offers an interpretation of the reality of arts producing organizations and on the other that the empirical analysis of these realities can supply new input for organization theory. As a practical example of artistic production the Author refers to an international chamber music festival. Close inspection of chamber music will reveal characteristics that apply to any type of organization. Sicca begins by looking at the nature of arts management and the arts manager. L.M.Sicca goes on to analyse the characteristics of the production process in the performing arts, which can be seen as communication taking place on three levels: between audience and performers (concept of “prosumer”); within the performing group (“listening ability”); between the author of the written text and the performer/interpreter (“concept of value”). Luigi Maria Sicca finishes by showing how in a symbolic-cultural framework the features identified in the paper can feed back into organization studies
L'educazione per la conquista dell'identità personale
No full textThe essay argues the need to pay attention to the educational growth and welfare of the individual personality that has relations in a certain context. The author reflects on the strategies through which the environment can facilitate or not the process of individual humanization
Six Characters In Search Of An Author
No full textProgram from the Little Theatre of Dallas' 1932 production of 'Six Characters In Search Of An Author,' written by Luigi Pirandello and directed by Charles Meredith. Setting arrangement by Alexandre Hogue. Cover art by Leon Dacus. Exhibitions by Olin Herman Travis and Kathryne Hail Travis
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