1,720,969 research outputs found
Outcomes among Patients with 1-Year Survival after Intensive Care Unit Treatment for COVID-19
No full textLong-term complications of COVID-19 in ICU survivors: What do we know?
Full text linkCoronavirus disease 2019 (COVID-19) has caused more than 175 million persons infected and 3.8 million deaths so far and is having a devastating impact on both low and high-income countries, in particular on hospitals and Intensive Care Units (ICU). The ICU mortality during the first pandemic wave ranged from 40% to 85% during the busiest ICU period for admissions around the peak of the surge, and those surviving are frequently faced with impairments affecting physical, cognitive, and mental health status, complicating the postacute phase of COVID-19, which in the pre-COVID period, were defined collectively as postintensive care syndrome (PICS). Long COVID is defined as four weeks of persisting symptoms after the acute illness, and post-COVID syndrome and chronic COVID-19 are the proposed terms to describe continued symptomatology for more than 12 weeks. Overall, 50% of ICU survivors suffer from new physical, mental, and/or cognitive problems at 1 year after ICU discharge. The prevalence, severity, and duration of the various impairments in ICU survivors are poorly defined, with substantial variations among published series, and may reflect differences in the timing of assessment, the outcome measured, the instruments utilized, and thresholds adopted to establish the diagnosis, the qualification of personnel delivering the tests, the resource availability as well diversity in patients' case-mix. Future longitudinal studies of adequate sample size with repeated assessments of validated outcomes and comparison with non-COVID-19 ICU patients are needed to fully explore the long-term outcome of ICU patients with COVID-19. In this article, we focus on chronic COVID-19 in ICU survivors and present state-of-the-art data regarding long-term complications related to critical illness and the treatments and organ support received
Delirium: lost in connection
No full textComment on:
The relationship between delirium duration, white matter integrity, and cognitive impairment in intensive care unit survivors as determined by diffusion tensor imaging: the VISIONS prospective cohort magnetic resonance imaging study*. [Crit Care Med. 2012
Publisher Correction to: Critical Illness Weakness, Polyneuropathy and Myopathy: Diagnosis, treatment, and long‐term outcomes (Critical Care, (2023), 27, 1, (439), 10.1186/s13054-023-04676-3)
No full textFollowing publication of the original article [1], an incomplete title was published. The word ‘Critical’ was missing from the title. The incorrect title is: Illness Weakness, Polyneuropathy and Myopathy: Diagnosis, treatment, and long-term outcomes The correct title is: Critical Illness Weakness, Polyneuropathy and Myopathy: Diagnosis, treatment, and long‐term outcomes The publisher sincerely apologize to the authors and readers for the inconvenience caused. The title has been updated in this publisher correction and the original article [1] has been corrected
Development of an Eye-Tracking Method for Diagnosing Delirium: Assessing Cognitive Function and Autonomic Nervous System Activity
No full textDelirium is a severe neuro-psychiatric condition characterized by a global deterioration of cognitive functions. The Confusion Assessment Method for the Intensive Care Unit scale, a test that evaluates a patient's cognitive abilities, is currently the most recommended method for assessing suspected delirium in intensive care units. However, this method faces challenges such as inadequate staff training, patient cooperation difficulties, and a lack of measurable quantitative metrics. While there are existing tests in the literature that use eye tracking to evaluate cognitive functions and assess the autonomic nervous system, there is currently no specific test available based on wearable eye tracking for diagnosing delirium. In this study, we investigated the application of a test to evaluate cognitive function and autonomic nervous system activity using eye tracking. The proposed protocol consists of four tests: the blank test, pro- and anti-saccade tests, and pupillometry test. In the first three tests, visual stimuli are presented to the subjects, and an algorithm has been developed to calculate their reaction times, which is the time interval from the presentation of the stimulus to the completion of the task. The extended uncertainty with a 95% confidence level introduced by the algorithm has been estimated as 12 ms using the Monte Carlo method. In the pupillometry test, a temporary light stimulus is provided, and parameters related to the pupil light reflex are calculated. The tests were conducted on a sample of 17 healthy male subjects, aged between 21 and 28 years, without visual or cognitive impairments. The results provide an overview of the cognitive functions and autonomic nervous system activity in the examined subjects. Additionally, the data collected from healthy subjects can be compared with individuals affected by delirium in future studies. To validate the reaction time algorithm, the Monte Carlo method was used, and a statistical analysis was conducted on the output data. The evaluation of the algorithm for detecting reaction times shows a root mean square error of 6 ms. The results of the pro- and anti-saccade tests show a statistically significant difference in detected reaction times (p-value ! 0.05), with the latter being higher due to the increased cognitive load required. The pupillometry test measured pupil light reflex parameters and compared them with those reported in the literature
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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