196,206 research outputs found
Rankin, R. M. (child)
No full textPhotograph from the C.R. Savage Portrait Studio. Name associated with the photograph: R. M. Ranki
FIGURE 4 in First record of Archanara neurica (Hübner, 1808) from the Iberian Peninsula (Lepidoptera: Noctuidae) according to DNA barcoding and internal male genitalia
No full textFIGURE 4. Habitat in the saltmarshes of Adventus near Trebujena, Cádiz, Spain (Manuel Pozas phot.).Published as part of Ortiz, A. S., Rubio, R. M., Ranki, T., Guerrero, J. J. & Yela, J. L., 2023, First record of Archanara neurica (Hübner, 1808) from the Iberian Peninsula (Lepidoptera: Noctuidae) according to DNA barcoding and internal male genitalia, pp. 431-441 in Zootaxa 5239 (3) on page 439, DOI: 10.11646/zootaxa.5239.3.7, http://zenodo.org/record/763503
Metadorcinus ranki Grossi
No full textMetadorcinus ranki Grossi & Vaz-de-Mello, new species Type material. Holotype ɗ: BRASIL, Santa Catarina, São Bento do Sul, Estação Rio Vermelho, XI– 2002, 850 m., I. Rank legit. Allotype Ψ: same data as holotype. Holotype and allotype ex. coll. E. and P. Grossi, deposited in the Coleção Entomológica Padre Jesus Santiago Moure, Universidade Federal do Paraná, Curitiba, Paraná, Brazil. Paratypes: 19 ɗɗ, 13 ΨΨ: 2 ɗɗ and 1 Ψ same data as holotype; 1 ɗ and 3 ΨΨ same data, XI- 2004; 3 ΨΨ same data, XII- 2003; 1 Ψ same data, 28 -I- 1998; 1 Ψ same data, 15 -I- 1999; 2 ɗɗ same data, I- 2006 and 9 ɗɗ same data, I- 2007, in Everardo and Paschoal Grossi collection, Nova Friburgo, Brazil; 1 ɗ and 1 Ψ same data, XII- 2003 in Fernando Z. Vaz-de-Mello collection, Lavras, Brazil; 1 ɗ and 1 Ψ same data, I- 2006, at Museum für Naturkunde der Humboldt Universität, Berlin, Germany; 1 ɗ and 1 Ψ same data, at The Natural History Museum, London, UK; 1 ɗ and 1 Ψ same data, I- 2006, at Canadian Museum of Nature, Ottawa, Canada; 1 ɗ, labeled: Rio Vermelho, SC [Santa Catarina], BRASIL, Dezembro 1956, A. Maller legit., ex Coll. Campos Seabra, in Museu Nacional, Universidade Federal do Rio de Janeiro, Brazil. Holotype. ɗ (Figs. 1–8, 12– 15, 20–21). Length 13 mm (including mandibles), width at elytra 4 mm. Color: Body completely black, dull, with mandibles, antennae, legs, scutellum, pronotal process, and ventral part of the body shiny; base of mandibles reddish-brown. Head: Shorter than wide, weakly depressed, with scattered punctures; punctures more dense and coalescent laterally; frons wide and smooth. Canthus triangular, projecting laterally; posterior margin rounded, protruding halfway into eye. Mandibles gradually upturned, as long as head; ventrally with row of yellow setae; apices weakly bifurcated, with a dorsal excavate projection; bent inside, with a flat inner bifurcated process; basal tooth horizontal and obtuse. Labrum trilobate, central lobe larger with small punctures and long setae. Gena with large scattered punctures and short setae. Gula weakly depressed with small, non-contiguous punctures. Labium oblong, laterally rounded, with large separated punctures. Mentum trapezoidal with small, separated punctures. Antennae small with ten antennomeres; all antennomeres with short setae; scape curved, wider apically; club segments distally tomentose. Prothorax: Pronotum transverse, subrectangular, as wide as head, with complete border; surface with small, distinct punctures; anterior angles sharply pointed, posterior angles rounded; an elevated bituberculate median process is presented anteriorly; process smooth and shiny, medially with a longitudinal rhomboidal depression. Scutellum: Scutellum glabrous, anteriorly concave, with sparse scattered punctures. Elytra: Striae indicated by parallel lines of punctures; interstriae with many much smaller, scattered punctures (mainly anteriorly); humeri acute; elytral margins almost parallel in basal half. Legs: Protibiae with 8–9 external, welldeveloped teeth increasing in size distally; serrate between teeth. Protibiae with inner margin basally sinuate, distally bearing many setae. Mesotibiae with a strong median tooth and a smaller proximal one on the outer margin; three smaller apical spines, one dorsal and two ventral; small scattered spines are also present. Metatibiae with a submedial acute tooth and 2 distal spines with dorsal spine bifurcated. Base of all tarsomeres densely setose. Ve n t e r: Epipleuron with scattered setose punctures, punctures more dense posteriorly. Prosternum with elongate punctures and short setae; prosternal apophysis conical and obtuse with scattered setae, smooth and shiny apically. Mesosternum punctate, punctures small and setose; mesepisternum granulate with large punctures. Metasternum with small punctures and metasternal suture visible along the whole disk, posteriorly with some small punctures; metaepisternum with large punctures medially. All abdominal ventrites with small irregular setose punctures; pygidium semicircular, densely granulose, with dense yellow setae, mainly laterally and medially. Genitalia: Genital capsule (Figs. 6–8) symmetric and complex, dorsal sclerite glabrous and wider basally. Apex of ventral sclerite with many long setae and a medial rectangular process, process whose length is 1 / 5 of its width; narrowed basally. Aedeagus (Figs. 3–5) almost symmetrical. Phallobase laterally lobed and narrowed basally. Parameres apically rounded with minute lateral setae and a sharp spineshaped basal process, curved inside. Median lobe sclerotized medially; apically widened, membranous with many small lateral and ventral spiculae. Allotype. Ψ (Figs. 9–11, 22– 23). Length 12 mm, maximum width 4 mm. As male except for the following characters. Head: Mandibles short with one tooth on the inner side, the tooth on the left mandible larger than the one of the right mandible. Head strongly punctate with many irregular non-contiguous punctures, coalescent at sides and near weak anteromedian depression; vertex concave; gena depressed with large punctures. Canthus dividing the eye for one third. Labrum concave with sparse, setose punctures, ventrally with dense setae. Labium with large punctures, setose anteriorly and laterally. Gula anteriorly smooth. Prothorax: Pronotum convex with weak longitudinal depression; anteriorly with smooth, medial, slightly bilobed process. Surface strongly punctate, sides rugose; pronotal borders setose anteriorly and posteriorly. Scutellum: Scutellum depressed anteriorly with few isolated punctures, basally smooth. Elytra: Elytra strongly punctate anteriorly, each elytron with rows of punctures and 5 smooth longitudinal lines in interstriae, (the third one is the largest), laterally with scattered short setae. Legs: Protibiae with 5–7 large external teeth, serrate elsewhere; dorsally with two longitudinal setose ridges, setae denser distally. Mesotibiae bifurcate apically with 6 external teeth decreasing in size distally; 3 ventral teeth are also present, with the medial one being the smallest. Metatibiae with 1 large external tooth and many smaller spines both dorsally and laterally, apically with a rectangular process and 3 teeth. Ven t er: Mesoepisternum weakly granulate with few scattered punctures. Metasternum with not contiguous setose punctures; metaepisternum with 2 rows of punctures. Genitalia: (Fig. 11) Form symmetrical. Dorsal plate smooth with two rounded basal lobes, styli enlarged apically, ventral plate setose and less sclerotized apically and internally. Variation. Male length: 10–13 mm, width 3–5 mm. Female length: 8–12, width 3–5 mm. Paratypes similar to holotype and allotype except the following characters: males with less developed mandibles (Figs. 12– 14) with less developed process and outer margin regularly convex, pronotum strongly punctured and less elevated, some females with protibial teeth less developed. Etymology. The new species is named after Mr. Ivo Rank, an expert collector and butterfly breeder who collected these and other interesting stag beetle specimens. Remarks. Metadorcinus ranki seems to be closely related to M. neotragus (Westwood, 1855) (Figs. 16, 28–29), from which it mainly differs in the stronger punctation of head, for the triangular shape of eye canthus, the different mandibular shape and for the absence of a strong pronotal process. Both species seem to be related to the group formed by M. cruentus (Figs. 18, 26–27), M. auritus Kriesche, 1922 (Fig. 17, 30-31), and M. ditomoides (Westwood, 1855) (Figs. 19, 24–25); the main differences are in the mandibles which are strongly upturned, in the more prominent canthus (except for large males of M. auritus and M. cruentus which show well developed canthi), and in the pronotal process which is more elevated. The new species is more robust than M. neotragus, M. cruentus, M. auritus, or M. ditomoides. Metadorcinus neotragus, M. cruentus, and M. ditomoides are known to occur in the same orographic region as M. ranki. M. neotragus is found in São Paulo and in the more southern Brazilian states, while M. cruentus is known only from Santa Catarina and Paraná, and M. ditomoides is known from Bahia, Rio de Janeiro, Santa Catarina, and Rio Grande do Sul. Entomologists have been collecting in the mountains in Santa Catarina for many years, which is undoubtedly why there are an abundance of records of lucanid species here. We hypothesize that more research in other highlands in Brazil will lead to the discovery of many other new species of Lucanidae. Based on the large number of new species and new localities for known species that have been found in the last few years by one of us (PCG), the highest lucanid diversity is in Serra dos Órgãos (Rio de Janeiro), Serra da Mantiqueira (Rio de Janeiro, São Paulo, and Minas Gerais), and Serra Geral (Paraná, Santa Catarina, and Rio Grande do Sul).Published as part of Grossi, Paschoal C. & Vaz-De-Mello, Fernando Z., 2007, A new species of Metadorcinus Kriesche from Brazil with notes on the genus (Coleoptera: Scarabaeoidea: Lucanidae), pp. 49-59 in Zootaxa 1478 on pages 50-56, DOI: 10.5281/zenodo.17680
FIGURE 5 in First record of Archanara neurica (Hübner, 1808) from the Iberian Peninsula (Lepidoptera: Noctuidae) according to DNA barcoding and internal male genitalia
No full textFIGURE 5. Neighbour-Joining tree (K2P; constructed with MEGA6; COI 5'> 600 bp) including 142 sequences of selected Archanara, Lenisa and Globia rooted with Denticucullus pygmina and Coenobia rufa as outgroups. The depth of each branch shows divergence between lineages. Bootstrap values> 50% are provided at major nodes. The scale bar represents 0.01 genetic difference.Published as part of Ortiz, A. S., Rubio, R. M., Ranki, T., Guerrero, J. J. & Yela, J. L., 2023, First record of Archanara neurica (Hübner, 1808) from the Iberian Peninsula (Lepidoptera: Noctuidae) according to DNA barcoding and internal male genitalia, pp. 431-441 in Zootaxa 5239 (3) on page 440, DOI: 10.11646/zootaxa.5239.3.7, http://zenodo.org/record/763503
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Improving the efficacy of PDL1 blockade by combination with oncolytic vaccines
No full textAim/Background: T-lymphocytes are at the center of anti-cancer strategies, however, their activation is not sufficient as immunosuppressive pathways limit their efficacy. Immune checkpoint inhibitors (ICIs) represented a revolutionary approach to preserve the functional state of T-cells. Nevertheless, the efficacy of ICIs relies on the presence of an undergoing immunological response. We hypothesized that the number of responders to immunotherapy would be increase by the combination of ICIs with our cancer vaccine platform PeptiCRAd.
Methods: We used B16OVA melanoma bearing mice, which were treated with a SIINFEKL-targeting PeptiCRAd combined with anti-PDL1 monoclonal antibody.
Results: First, we optimized the combination of the two monotherapies. In fact, by overlapping PeptiCRAd and anti-PDL1 treatment we achieved a significant increase in median survival (+40% for Combo compared to monotherapies). Concerning the functional state of TILs we found that the immune therapies would enhance the percentage of activated T-lymphocytes and reduce the amount of exhausted cells compared to placebo. As expected, while PeptiCRAd monotherapy could increase the number of antigen specific CD8 T-cells only its combination with PDL1 blockade could significantly increase the ratio between activated and exhausted Pentamer positive cells (p = 0,0058). We observed that the anatomical location deeply influenced the state of CD4 and CD8 T-lymphocytes. In fact, TIM-3 expression was increased by 2 folds on Tumor infiltrating lymphocytes (TILs) compared to splenic and lymphoid T-cells. In addition, we investigated the effect of anti-adenoviral pre-existing immunity upon the combination of oncolytic vaccines (i.e. PeptiCRAd) with PDL1 blockade. Interestingly we found that pre-immunization with oncolytic adenovirus did not reduce the efficacy of the therapy. This is an important finding since the vast majority of the population shows immunity against serotype 5 adenoviruses.
Conclusions: In conclusion, our data shows that PeptiCRAd can increase the number of antigen-specific cells that can be protected by the disruption of the PDL1-PD1 axis. This ultimately results in a prolonged survival of mice and improved control of non-injected primary and secondary tumors.
Legal entity responsible for the study: University of Helsinki
Funding: Cancer Society of Finland, Novo-Seeds, Tekes
Disclosure: S. Pesonen, T. Ranki: Employed in PeptiCRAd Oy, a biotech company owning the patent based on the PeptiCRAd oncolytic vaccine platform which is used in this research. V. Cerullo: Member of the advisory board of PeptiCRAd Oy, a biotech company owning the patent based on the PeptiCRAd oncolytic vaccine platform which is used in this research. All other authors have declared no conflicts of interest
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
Simulation of thermal plant optimization and hydraulic aspects of thermal distribution loops for large campuses
No full textFollowing an introduction, the author describes Texas A&M University and its utilities system. After that, the author presents how to construct simulation models for chilled water and heating hot water distribution systems. The simulation model was used in a $2.3 million Ross Street chilled water pipe replacement project at Texas A&M University. A second project conducted at the University of Texas at San Antonio was used as an example to demonstrate how to identify and design an optimal distribution system by using a simulation model. The author found that the minor losses of these closed loop thermal distribution systems are significantly higher than potable water distribution systems. In the second part of the report, the author presents the latest development of software called the Plant Optimization Program, which can simulate cogeneration plant operation, estimate its operation cost and provide optimized operation suggestions. The author also developed detailed simulation models for a gas turbine and heat recovery steam generator and identified significant potential savings. Finally, the author also used a steam turbine as an example to present a multi-regression method on constructing simulation models by using basic statistics and optimization algorithms. This report presents a survey of the author??s working experience at the Energy Systems Laboratory (ESL) at Texas A&M University during the period of January 2002 through March 2004. The purpose of the above work was to allow the author to become familiar with the practice of engineering. The result is that the author knows how to complete a project from start to finish and understands how both technical and nontechnical aspects of a project need to be considered in order to ensure a quality deliverable and bring a project to successful completion. This report concludes that the objectives of the internship were successfully accomplished and that the requirements for the degree of Degree of Engineering have been satisfied
- …
