1,721,646 research outputs found
Robotic natural orifice translumenal endoscopic surgery and laparoendoscopic single-site surgery: current status
DOPAMINE SULFOTRANSFERASE IS BETTER DEVELOPED THAN PARA-NITROPHENOL SULFOTRANSFERASE IN THE HUMAN FETUS
The distribution patterns of two forms of sulphotransferase were studied in human adult and fetal tissues. One form was studied with p-nitrophenol as substrate and it is referred to as 'TS'. The other form was studied with dopamine as substrate and it is referred to as 'TL'. The activities of TS (pmol X min-1 X mg-1; mean +/- SD) were 1.077 +/- 293 (adult liver; n = 6), 97.8 +/- 26.4 (fetal liver; n = 8); 38.0 +/- 12.8 (adult kidney; n = 5), 28.5 +/- 21.5 (fetal kidney; n = 8); 78.9 +/- 21.3 (adult lung, ex-smokers; n = 5), 83.0 +/- 23.1 (adult lung, smokers; n = 5), 25.8 +/- 10.0 (fetal lung; n = 8), 140.8 +/- 18.9 (ileum; n = 5), 68.6 +/- 30.7 (ascending colon; n = 5), 28.6 +/- 10.8 (fetal gut; n = 8), 23.9 +/- 14.5 (placenta; n = 5). The adult to fetal ratios for TS were 11.0 (liver), 1.3 (kidney), 3.1 (lung) and 2.6 (gut). The activities of TL were 28.9 +/- 17.4 (adult liver; n = 6), 97.2 +/- 52.3 (fetal liver; n = 8); 10.3 +/- 4.7 (adult kidney; n = 5), 37.7 +/- 29.9 (fetal kidney; n = 8); 79.6 +/- 18.8 (adult lung, exsmokers; n = 5), 76.3 +/- 23.7 (adult lung, smokers; n = 5), 98.2 +/- 55.0 (fetal lung; n = 8); 391.2 +/- 37.3 (ileum; n = 5), 161.5 +/- 66.0 (ascending colon; n = 5), 200.6 +/- 137.1 (fetal gut; n = 8), 21.8 +/- 13.6 (placenta; n = 5). The adult to fetal ratios for TL were 0.3 (liver), 0.3 (kidney), 0.8 (lung) and 0.8 (gut). TL is better developed than TS in the human fetus. These data also show that TS and TL are more active in ileum than colon mucosa of adult subjects. Smoking does not affect the enzymes in the lung
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Human adult and foetal liver sulphotransferases: inhibition by mefenamic acid and salicylic acid
Uridine 5'-diphosphoglucuronic acid (UDPGLcUA) in the human fetal liver, kidney and placenta
SULFOTRANSFERASE AND ITS SUBSTRATE - ADENOSINE-3'-PHOSPHATE-5'-PHOSPHOSULPHATE IN HUMAN-FETAL LIVER AND PLACENTA
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Adrenalectomy
Multiple series have demonstrated the benefits of laparoscopic adrenalectomy techniques when compared to open surgery. Laparoendoscopic single-site surgery (LESS) for adrenal gland has been effectively performed for a number of indications and a wide variety of approaches have been described. That said, there are still obvious technical difficulties associated with LESS and, in particular, LESS adrenalectomy is regarded as a highly challenging procedure. Reduced port laparoscopic surgery has been implemented as a way of moving forward towards the path of scarless surgery by overcoming the constraints of LESS. Herein we describe the techniques for reduced port laparoscopic adrenalectomy (RPLA), in both supine and prone position. As far as the approach is concerned, both transperitoneal and retroperitoneal techniques have demonstrated similar outcomes with appropriate patient selection criteria. The anterior transperitoneal route is used with the patient is supine position. This technique can present few advantages, including easy positioning of the patient on the operative table, clear evidence of anatomical landmarks, wider exposure of the adrenal gland, early ligature of the main adrenal vein before gland manipulation, the possibility to perform a bilateral procedure, easy immediate conversion to open in the case of major bleeding. Adrenalectomy with the patient in the prone position can also be used. Overall, RPLA represents a viable option in the surgical management of adrenal diseases. Its main feature is represented by the possibility of restoring the triangulation needed to optimize working angles while minimizing the scar associated with the procedure
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