3,134 research outputs found

    Core Journal Lists: Classic Tool, New Relevance

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    Reviews the historical context of core journal lists, current uses in collection assessment, and existing methodologies for creating lists. Outlines two next generation core list projects developing new methodologies and integrating novel information/data sources to improve precision: a national-level core psychology list and the other a local institutional core list for the interdisciplinary field of urban studies and planning. The paper is based on the authors’ panel presentation at the 2009 ACRL National Conference (Seattle, Washington) titled “Core Journal Lists Re-viewed and Re-imagined.”This is an electronic version of an article published in Robin A. Paynter, Rose M. Jackson & Laura Bowering Mullen (2010): Core Journal Lists: Classic Tool, New Relevance, Behavioral & Social Sciences Librarian, 29:1, 15-31. Behavioral & Social Sciences Librarian is available online at: http://www.tandfonline.com, http://dx.doi.org/10.1080/01639260903571096Peer reviewe

    Alan Bennett's The History Boys

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    This article explores Alan Bennett’s The History Boys, as a contemporary play, which manages to be highly entertaining and at the same time educationally enriching. While not written for adolescents, they have flocked to see the play onstage. Among other topics, the author focuses on the different methods of teaching history of three teachers at a secondary school in the North of England in the 1980s. Dramatic conflict and humour derive from the way the author pits against each other the view of history held by his teacher-protagonists, often throwing the students into a state of intellectual confusion. Which teacher are they to believe? Through a close reading of the play, it would appear that the spectator, including an adolescent spectator, is left free. He or she can choose to identify with one of the teachers and the view of history she or he is purporting, or simply watch the play, appreciating the challenging intellectual debate it sets forth

    Did Plant Patents Create the American Rose?

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    The Plant Patent Act of 1930 was the first step towards creating property rights for biological innovation: it introduced patent rights for asexually-propagated plants. This paper uses data on plant patents and registrations of new varieties to examine whether the Act encouraged innovation. Nearly half of all plant patents between 1931 and 1970 were for roses. Large commercial nurseries, which began to build mass hybridization programs in the 1940s, accounted for most of these patents, suggesting that the new intellectual property rights may have helped to encourage the development of a commercial rose breeding industry. Data on registrations of newly-created roses, however, yield no evidence of an increase in innovation: less than 20 percent of new roses were patented, European breeders continued to create most new roses, and there was no increase in the number of new varieties per year after 1931.

    Felton M. Johnston with unidentified women in the White House Rose Garden.

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    Typed description: \u27Photograph taken in the White House Rose Garden on Friday, August 21, 1964\u27https://egrove.olemiss.edu/fmjohnston/1290/thumbnail.jp

    Molecular basis of gene-environment interactions in the pathogenesis of asthma and COPD

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    The origins of respiratory disease, such as asthma in childhood and COPD in later life are unclear. Maternal smoking during pregnancy and low birth weight is associated with increased risk of asthma, poor lung function in adults and COPD in old age. Exposure to oxidative stress and poor nutrition in utero is thought to cause damage to the lung and alter the normal course of lung development.Glutathione S-transferases (GST) are potent antioxidants. In this work, genetic polymorphisms that alter GST enzyme activity were genotyped in a family-based childhood asthma cohort (341 families, n = 1508) and analysed to investigate whether they alter the risk of developing asthma when individuals are exposed to environmental tobacco smoke. Real-time PCR based copy number variation methodology was developed to genotype the common gene deletion polymorphism of GSTT1 and GSTM1 genes, for other GST genes (GSTP1 and GSTO2) SNP haplotypes were constructed. A rare GSTO2 haplotype was negatively associated with asthma susceptibility, atopy severity, and FEV1 values. Asthmatic children with a GSTT1 gene deletion, or a common GSTP1 haplotype, developed more severe asthma compared to individuals with a GSTT1 gene or non-carriers of the GSTP1 haplotype. Total IgE levels were increased in GSTT1*0 individuals when exposed to tobacco smoke in early life, suggesting a gene-environment interaction. GSTO2 may be a shared susceptibility locus for asthma in childhood and COPD in later life.Animal models of maternal protein-restriction during pregnancy can induce hypertension, diabetes and endothelial dysfunction in offspring and in some of these models alterations to lung gene expression and lung architecture have been reported. This work established that a rat model of maternal dietary protein-restriction during pregnancy known to induce hypertension in the offspring, results in persistent alterations to the expression of genes in the lungs of adult offspring (120 days), including genes involved in glucocorticoid action (Hsd11b2), growth (Igf1 & 2 and Pcdh1) and alveolar development (Tp53). Lung microRNA expression profiles were also altered in response to exposure to protein restriction in utero. These findings suggest a role for nutritional programming in respiratory disease susceptibility in later life and a role for microRNAs in the study of the developmental origins of health and disease in general. Further work will include the investigation of epigenetic mechanisms that control nutritional programming in lungs of animals exposed to protein-restriction in utero.This work has demonstrated that GST polymorphism is a risk factor for childhood asthma and certain genotypes can offer some protection against the development of severe asthma. There was little evidence to suggest that GST polymorphism modulates the effects of smoke exposure in early life. In addition, we have demonstrated that maternal diets that are poor in nutrition could predispose her offspring to respiratory disease in later life by altering the course of normal lung development in early life or response to environmental stimuli in later life

    Chronicles of Oklahoma

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    Article describes the life of the author traveling into the Oklahoma frontier and settling the small community of Catesby. F. P. Rose's grandmother, Ella M. Rose, established the sod store that would become an important maker on the homesteader trail. F. P. Rose also lists the pioneers who settled Catesby's vicinity

    Sinkhole genesis and evolution in Apulia, and their interrelations with the anthropogenic environment

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    Sinkhole development occurs in many areas of the world where soluble rocks crop out. Sinkholes are generally the surface expression of the presence of caves and other groundwater flow conduits in carbonate rocks, which are solutionally enlarged secondary permeability features. Their formation may be either natural or caused by man's activities. In both cases, heavy consequences have to be registered on the anthropogenic environment and related infrastructures. Knowledge of the mechanism of formation of this subtle geohazard is therefore necessary to planners and decision makers for performing the most appropriate and suitable programs of land use and development. The Apulia region of southern Italy is characterized for most of its extension by carbonate rocks, which makes it one of the most remarkable example of karst in the Mediterranean Basin. Based on analysis of literature and in situ surveys, including caving explorations, we have identified in Apulia three main types of possible mechanisms for sinkhole formation: 1) collapse of a chamber in a natural cave or in man-made cavities; 2) slow and gradual enlargement of doline through dissolution; 3) settlement and internal erosion of filling deposits of pre-existing dolines. Since sinkhole formation very often affects directly the human settlements in Apulia, and have recently produced severe damage, some considerations are eventually presented as regards the interrelationships between sinkholes and the anthropogenic environment. © 2004 Author(s)

    Social Metadata for Libraries, Archives and Museums. Part 3: Recommendations and Readings

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    Recommendations on social metadata features most relevant to libraries, archives, and museums and an annotated reading list of the literature the research group consulted during our research. We believe it is riskier to do nothing and become irrelevant to our user communities than to start using social media features
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