327 research outputs found

    Topica, critica, dialettica. Possibili influenze platoniche nel De Nostri Temporis Studiorum Ratione di Giambattista Vico?

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    TOPICS, CRITICS, DIALECTICS. ARE THERE PLATONIC INFLUENCES IN VICO’S DE NOSTRI TEMPORIS STUDORIUM RATIONE? The aim of this paper is to analyze some possible influences of Plato’s dialogues on Giambattista Vico’s thought. The author puts the focus on the integration between topics and critics proposed in De nostri temporis studiorum ratione, and assumes that Vico based this important theory on Plato’s dialectics, which he rethinked in order to face the challenges of modern philosophy

    Cryotherapy for docetaxel-induced hand and nail toxicity: randomised control trial

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    Purpose This study investigated the efficacy and safety of cryotherapy, in the form of frozen gel gloves, in relation to docetaxel-induced hand and fingernail toxicities. Patients and methods After piloting with 21 patients, a consecutive series sample of patients (n=53) prescribed docetaxel every 3 weeks, for a minimum of three cycles, was enrolled in this randomised control trial. Participants acted as their own control, with the frozen gel glove worn on one randomised hand for 15 min prior to infusion, for the duration of the infusion, and for 15 min of after completion of treatment. Hand and nail toxicities were evaluated by two blinded assessors according to CTCAE.v4 criteria. To assess the potential for cross-infection of multi-use gloves, microbial culture and sensitivity swabs were taken of each glove at every tenth use. Results Of the 53 participants enrolled in the main study, 21 provided evaluable data. There was a 60%withdrawal rate due to patient discomfort with the intervention. Themean incidence and severity of toxicities in all evaluable cycles in control and intervention hands respectively were erythroderma grade 1 (5/5 %), nail discolouration grade 1 (81/67 %), nail loss grade 1 (19/19 %) and nail ridging grade 1 (57/57 %). No significant differences were determined between hand conditions in terms of time to event, nor in terms of toxicity in gloved and nongloved hands. Conclusion While cryotherapy in the form of frozen gloves for the cutaneous toxicities associated with docetaxel is safe, its limited efficacy, patient discomfort and some logistical issues preclude its use in our clinical setting.No Full Tex

    Infection Control and Prevention in Community Settings

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    Self-archiving is not yet supported by this publisher. Please refer to the publisher's website or contact the author(s) for more information.Griffith Health, School of Nursing and MidwiferyNo Full Tex

    COVID‐19: Lessons to be learnt from a once‐in‐a‐century global pandemic

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    The year 2020 will mark a once‐in‐a‐century global event: the outbreak and pandemic of COVID‐19. On the 31 December 2019 the World Health Organization (WHO) reported a cluster of pneumonia‐like cases of a novel coronavirus zoonosis in Wuhan City, Hubei Province, China. The outbreak was due to a new or novel coronavirus, which would later be called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2)

    Nurse-led trials of medical devices: general principles and good practice

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    Aim To provide an overview of governance issues relating to medical-device trials and practical advice for nurses wishing to initiate or lead them. Background Medical-device trials, which are formal research studies that examine the benefits and risks of therapeutic medical devices, have traditionally been the domain of physicians and scientists. The role of nurses in these trials has historically been as data collectors or co-ordinators rather than as principal investigators. However, nurses have more recently played an increasing role in initiating and leading medical device trials. Review methods A review article of nurse-led trials of medical devices. Discussion Central to the quality and safety of all clinical trials is adherence to the International Conference on Harmonisation Guidelines for Good Clinical Practice, which is the internationally agreed standard for the ethically and scientifically sound design, conduct and monitoring of a medical-device trial, as well as the analysis, reporting and verification of the data derived from that trial. Considerations include the class of the medical device, type of trial, regulatory status of the device, implementation of standard operating procedures, obligations of the trial sponsor, indemnity of relevant parties, scrutiny of the trial conduct, trial registration, and reporting and publication of the results. Conclusion Nurse-led trials of medical devices are demanding but rewarding research enterprises. As nursing practice and research increasingly embrace technical interventions, it is vital that nurse researchers contemplating such trials understand and implement the principles of good clinical practice to protect study participants and the research team.No Full Tex

    Compliance, peritoneal dialysis and chronic kidney disease: lessons from the literature

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    Poor patient compliance with peritoneal dialysis (PD) has signifi cant adverse effects on morbidity and mortality rates in individuals with chronic kidney disease (CKD). It also adds to the resource burdens of healthcare services and providers. This paper explores the notion of PD compliance in patients with CKD with reference to the relevant published literature. The analysis of the literature reveals that 'PD compliance' is a complex and challenging construct for both patients and health professionals. There is no universal defi nition of compliance that is widely adopted in practice and research, and therefore a lack of consensus on how to determine 'compliant' patient outcomes. There are also multiple and interconnected determinants of PD compliance that are context-bound, which healthcare professionals must be aware of, and which makes producing consensus of measuring PD compliance diffi cult. The complexity of the interventions required to produce even a modest improvement in PD compliance, which are described in this paper, are signifi cant. Compliance with PD and other treatments for CKD is a multidimensional, context-bound concept, that to date has tended to efface the role and needs of the renal patient. We conclude the paper with the implications for contemporary practice.Full Tex

    Paramedic knowledge of infectious disease aetiology and transmission in an Australian Emergency Medical System

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    Introduction: Paramedics and other emergency health workers are exposed to infectious disease particularly when undertaking exposure-prone procedures as a component of their everyday practice. This study examined paramedic knowledge of infectious disease aetiology and transmission in the pre-hospital care environment. Methods: A mail survey of paramedics from an Australian ambulance service (n=2274) was conducted. Results: With a response rate of 55.3% (1258/2274), the study demonstrated that paramedic knowledge of infectious disease aetiology and modes of transmission was poor. Of the 25 infectious diseases included in the survey, only three aetiological agents were correctly identified by at least 80% of respondents. The most accurate responses for aetiology of individual infectious diseases were for HIV/AIDS (91.4%), influenza (87.4%), and hepatitis B (85.7%). Poorest results were observed for pertussis, infectious mononucleosis, leprosy, dengue fever, Japanese B encephalitis and vancomycin resistant enterococcus (VRE), all with less than half the sample providing a correct response. Modes of transmission of significant infectious diseases were also assessed. Most accurate responses were found for HIV/AIDS (85.8%), salmonella (81.9%) and influenza (80.1%). Poorest results were observed for infectious mononucleosis, diphtheria, shigella, Japanese B encephalitis, vancomycin resistant enterococcus, meningococcal meningitis, rubella and infectious mononucleosis, with less than a third of the sample providing a correct response. Conclusions: Results suggest that knowledge of aetiology and transmission of infectious disease is generally poor amongst paramedics. A comprehensive in-service education infection control programs for paramedics with emphasis on infectious disease aetiology and transmission is recommended

    Fa'afaletui: A Famework for the Promotion of Renal Health in an Australian Samoan Community

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    Purpose: Samoan communities in Australia exhibit a disproportionate rate of kidney disease compared with other Australians. This article describes a research project that used a culturally sensitive framework, Fa'afaletui, to help reduce the barriers of language and culture and increase our understanding of the factors contributing to kidney disease, in one Samoan community in Australia. Design: Semistructured group interviews were undertaken with Samoan community families and groups. The interviews were analyzed according to key concepts embedded in the Fa'afaletui framework. Findings: Four factors associated with health risks in this Samoan community emerged: diet and exercise, issues related to the collective (incorporating the village, church, and family), tapu or cultural protocols, and the importance of language. Conclusions: The findings suggest that future kidney health promotion initiatives within this Samoan community will be more effective if they are sensitive to Samoan cultural norms, language, and contexNo Full Tex
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