592 research outputs found
Population balance equation for collisional breakage: A new numerical solution scheme and its convergence
No full text<p><strong>Synopsis</strong></p><p>These files represent a reference implementation of the finite volume method for the solution of the discretised population balance equation for collisional breakge. Several test cases are provided. </p><p>Implementation language: Matlab (FORTRAN-derivative)</p><p>The method and its capabilities are described in<br>P. Kuswah, A. Das, J. Saha, A. Bück, "Population balance equation for collisional breakage: A new numerical solution scheme and its convergence", Communications in Nonlinear Science and Numerical Simulation, vol 121, 107244, 2023. </p><p>If the method or code is used in other work, cite<br>P. Kuswah, A. Das, J. Saha, A. Bück, "Population balance equation for collisional breakage: A new numerical solution scheme and its convergence", Communications in Nonlinear Science and Numerical Simulation, vol 121, 107244, 2023. </p><p><strong>License</strong></p><p>The implementation is distributed as-is without taking over any responsibility by the authors or their affiliated institutions for potential damages resulting from its use. </p><p>The implementation is made available under Creative Commons Attribution Non Commercial No Derivatives 4.0 International. </p><p><strong>Folder contents</strong></p><p>The reference implementations are provided for the cases discussed in the mentioned publication. The implementation of the finite volume methode is stored in the sub-folders "DPBE_Brk", calling sequence and required initialisiations are given in the files "Main_FPT.m".</p><p>In case of problems, bug reports, feel free to contact any author.</p><p>On behalf of all authors,</p><p>Andreas Bück<br>Institute of Particle Technology<br>Friedrich-Alexander-Universität Erlangen-Germany<br>[email protected]<br>www.spg.forschung.fau.de</p><p> </p><p>v1.0: 31.08.2023</p>
A distributed amplifier system for bilayer lipid membrane (BLM) arrays with noise and individual offset cancellation
No full textLipid bilayer membrane (BLM) arrays are required for high throughput analysis, for example drug screening or advanced DNA sequencing. Complex microfluidic devices are being developed but these are restricted in terms of array size and structure or have integrated electronic sensing with limited noise performance. We present a compact and scalable multichannel electrophysiology platform based on a hybrid approach that combines integrated state-of-the-art microelectronics with low-cost disposable fluidics providing a platform for high-quality parallel single ion channel recording. Specifically, we have developed a new integrated circuit amplifier based on a novel noise cancellation scheme that eliminates flicker noise derived from devices under test and amplifiers. The system is demonstrated through the simultaneous recording of ion channel activity from eight bilayer membranes. The platform is scalable and could be extended to much larger array sizes, limited only by electronic data decimation and communication capabilities
Semi-abelian analogues of Schanuel conjecture and applications
No full textIn this article we study semi-abelian analogues of Schanuel conjecture. As showed by the first author, Schanuel conjecture is equivalent to the Generalized Period conjecture applied to 1-motives without abelian part. Extending her methods, the second, the third and the fourth authors have introduced the abelian analogue of Schanuel conjecture as the Generalized Period conjecture applied to 1-motives without toric part. As a first result of this paper, we define the semi-abelian analogue of Schanuel conjecture as the Generalized Period conjecture applied to 1-motives. C. Cheng et al. proved that Schanuel conjecture implies the algebraic independence of the values of the iterated exponential and the values of the iterated logarithm, answering a question of M. Waldschmidt. The second, the third and the fourth authors have investigated a similar question in the setup of abelian varieties: the Weak Abelian Schanuel conjecture implies the algebraic independence of the values of the iterated abelian exponential and the values of an iterated generalized abelian logarithm. The main result of this paper is that a Relative Semi-abelian conjecture implies the algebraic independence of the values of the iterated semi-abelian exponential and the values of an iterated generalized semi-abelian logarithm
Internet-of-Forensic (IoF): A blockchain based digital forensics framework for IoT applications
No full textDigital forensic in Internet-of-Thing (IoT) paradigm is critical due to its heterogeneity and lack of transparency of evidence processing. Moreover, cross-border legalization makes a hindrance in such process pertaining to the cloud forensic issues. This urges a forensic framework for IoT which provides distributed computing, decentralization, and transparency of forensic investigation of digital evidences in cross-border perspectives. To this end, we propose a framework for IoT forensics that addresses the above mentioned issues. The proposed solution called Internet-of-Forensics (IoF) considers a blockchain tailored IoT framework for digital forensics. It provides a transparent view of the investigation process that involves all the stakeholders (e.g., heterogeneous devices, and cloud service providers) in a single framework. It uses blockchain-based case chain to deal with the investigation process including chain-of-custody and evidence chain. Consensus is used for consortium to solve the problems of cross-border legalization. This is also beneficial for a transparent and ease of forensic reference. The programmable lattice-based cryptographic primitives produce reduced complexities. It shows benefits for power-aware devices and puts an add-on to the novelty of the presented idea. IoF is generic; hence, it can be used by autonomous security operation centers, cyber-forensic investigators and manually initiated evidences under chain-of-custody for man-made crimes. Security services are assured as required by the framework. IoF is experimented and compared with the other state-of-the-art frameworks. The outcomes and analysis prove the efficiency of IoF concerning complexity, time consumption, memory and CPU utilization, gas consumption, and energy analysis
Meghnad Saha: his life in science and politics
No full textThis biography is a short yet comprehensive overview of the life of Meghnad Saha, the mastermind behind the frequently used Saha equations and a strong contributor to the foundation of science in India. The author explores the lesser known details behind the man who played a major role in building scientific institutions in India, developed the breakthrough theory of thermal ionization, and whose fervor about India’s rapid progress in science and technology, along with concern for uplifting his countrymen and optimizing resources, led him to eventually enter politics and identify the mismanagement of many programs of national importance to Parliament. This book is free of most academic technicalities, so that the reader with general scientific knowledge can read and understand it easily. One interested only in Saha’s contribution to physics can pick up just that part and read it. Conversely, the average reader may skip the technical chapters, and read the book without loss of continuity or generality to still get a coherent picture. This work touches on all aspects of Saha’s multidimensional personality, which overflows in the pages of his periodical, Science and Culture,as well as his many speeches, debates and discussions in Parliament, all of which is appropriately conveyed in this book
Yakut author Nikolay Luginov and his stories
No full text1970 sonrasında yazmaya başladığı ilk hikayeleri ile edebiyat dünyasına adım atan Nikolay Luginov, Saha (Yakut) edebiyatının önde gelen temsilcilerinden birisidir.
Nikolay Luginov'un hikayeleri üzerinde ayrıntılı bir çalışma yapmak ve yazarın modern Yakut edebiyatındaki yerini ortaya koymak amacıyla yapılan bu tezde hikayeler üzerinde metin merkezli bir inceleme yapılmıştır.
Tezimizin "Giriş" bölümünde, tezin amacı, araştırma yöntemleri ile Saha (Yakut) Türkleri ve Saha (Yakut) edebiyatının gelişim süreçleri hakkında genel bir bilgi verilmiştir.
Birinci bölümde, Nikolay Luginov'un hayatı, edebi kişiliği ve eserleri ele alınmıştır. Bu bölümde Nikolay Luginov'un, hikayeden roman türüne geçiş sürecine ve yazarın son çalışmalarına değinilmiştir.
Çalışmamızın ikinci bölümünde, Nikolay Luginov'un üç hikayesi tahlil edilmiş, hikaye tahlillerinde önce olay örgüsü, ardından özet, şahıs kadrosu, zaman ve mekan incelemesi yapılmıştır. Ayrıca hikayelerde yer alan mitolojik ve geleneksel unsurlar ele alınmıştır.
“Sonuç” bölümünde ise Nikolay Luginov’un edebi kişiliği ve eserleri üzerinde yapılan incelemenin sonuçları, yazarın dünya görüşü çercevesinde değerlendirilmiştir.One of the leading representatives of Saha (Yakut) literatureNikolay Luginov involved into the literary word with his first storieswhich he started to write after 1970.
In order to present a detailed study on the stories of Nikolay Luginov and to reveal the place of the author in Saha (Yakut) literatur, the stories of Luginov was examined with a text-cnetered approach.
General information about Yakut Turks and development processes of Yakut literature and aim of the thesis, research methods are given in the “Introduction” section of the thesis.
In the first chapter, Nikolay Luginov’s life, literary identity and his Works were discussed. In the section,Nikolay Luginov’s literary transition process from story to lovel and the aothor’s recent works were eveluated.
Three storiew of Nikolay Luginov were analyzed in the second part of the study. First the plot then the summary, charecters, time and space were examined in the story analysis. Moreover, the mythological and traditional elements in the stories were discussed.
The results of the study into the literary identiy and Works of Nikolay Luginov were presented within the framework of the auuthor’s word view in the conclusion section
Interphase phosphorylation of H1.4 in transcriptional control
No full textSubmission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2020-12-01The student, Ankita Saha, accepted the attached license on 2018-11-30 at 13:35.The student, Ankita Saha, submitted this Dissertation for approval on 2018-11-30 at 13:42.This Dissertation was approved for publication on 2018-12-03 at 09:02.DSpace SAF Submission Ingestion Package generated from Vireo submission #13162 on 2019-02-07 at 14:18:41Made available in DSpace on 2019-02-07T20:36:05Z (GMT). No. of bitstreams: 3
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Previous issue date: 2018-12-03Embargo set by: Seth Robbins for item 109846
Lift date: 2021-02-07T20:36:09Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 109846
Lift date: 2021-02-07T20:39:46Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 109846
Lift date: 2021-02-07T20:44:35Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 109846 on 2021-02-08T10:15:22Z.Core histone variants such as H2A.X and H3.3 serve specialized roles in chromatin processes that depend on the genomic distributions and amino acid sequence differences of the variant proteins. Modifications of the variants alters interactions with other chromatin components and thus the protein’s functions. Similarly, growing evidence suggests that amino acid sequence variance also modifies the functions of H1 linker histone family members, altering their effects on transcription, differentiation and development. These data are contrary to the notion that linker histones are redundant repressors. For example, complete loss of H1 does not result in an overall increase in transcription, implying that not all H1 variants are associated with repression. Furthermore, certain modifications of H1 variants can confer distinct roles. On the one hand, phosphorylation of H1 reportedly results in its release from chromatin and subsequent transcription of HIV-1 genes. On the other hand, recent evidence has shown that the phosphorylated H1 may in fact be associated with active promoters. This conflict suggests that different H1 isoforms may play distinct functional roles. Here, we provide the first genome- wide evidence that when phosphorylated, H1.4 remains associated with active promoters and may even play a role in transcription activation.
Using novel, highly specific antibodies, we generated the first genome-wide view of the H1.4 isoform phosphorylated at serine 187 (pS187-H1.4) in estradiol-inducible MCF7 cells. We observe that pS187-H1.4 is enriched primarily at the transcription start sites (TSSs) of genes activated by estradiol treatment, and depleted from those that are repressed. We also show that pS187-H1.4 strongly associates with ‘early estrogen response’ genes and co-localizes with active RNA polymerase signals.
Based on observations presented here, we propose that interphase phosphorylation at S187 by CDK9 represents an early event required for gene activation. This event may also be involved in release of promoter proximal polymerases to begin elongation by interacting directly with the polymerase or other parts of the transcription machinery. Although we focused on estrogen- responsive genes, taking into account previous evidence of H1.4 enrichment at promoters of pluripotency genes, we propose that H1.4 phosphorylation for gene activation may be a more general and global phenomenon
Production and application of biodiesel from waste cooking oil
No full textBiodiesel has been identified as an alternative and promising fuel source to reduce the dependency on conventional fossil fuel in particular diesel. In this work, waste cooking oil (WCO) of restaurants is considered to produce biodiesel. A wellestablished transesterification reaction by sodium hydroxide (NaOH) catalytic and supercritical methanol (CH3OH) methods are applied to obtain biodiesel. In the catalytic transesterification process, biodiesel and glycerine are simultaneously produced. The impact of temperature, methanol/WCO molar ratio and sodium hydroxide concentration on the biodiesel formation were analysed and presented. It was found that the optimum 95% of biodiesel was obtained when methanol/WCO molar ratio was 1:6 under 873 K temperature with the presence of 0.2% NaOH as a catalyst. The waste cooking oil blend proportions were 10%, 15%, 20% and 25% and named as bio-diesel blends B-10, B-15, B-20, and B-25, respectively. Quality of biodiesel was examined according to ASTM 6751: biodiesel standards and testing methods. Important fuel properties of biodiesel, such as heating value, cetane index, viscosity, and others were also investigated. A four-stroke single cylinder naturally aspirated DI diesel engine was operated using in both pure form and as a diesel blend to evaluate the combustion and emission characteristics of biodiesel. Engine performance is examined by measuring brake specific fuel consumption and fuel conversion efficiency. The emission of carbon monoxide (CO), carbon dioxide (CO2), nitrogen oxides (NOx), and others were measured. It was measured that the amount of CO2 increases and CO decreases both for pure diesel and biodiesel blends with increasing engine load. However, for same load, a higher emission of CO2 from biodiesel blends was recorded than pure diesel.S. S. Tuly, M. Saha, N. N. Mustafi, M. R. I. Sarke
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