1,793 research outputs found
Author response: India and China in Africa: a comparative perspective of the oil industry by Raj Verma
Earlier this month Ian Taylor reviewed India and China in Africa, a new book about Asian engagement in the West African oil industry. Here, the book’s author Raj Verma responds to Taylor’s comments, outlining the rationale and evidence for the framework used in the study. India and China in Africa: A comparative perspective of the oil industry. Raj Verma. London: Routledge. 2017
Real-time co-management of electricity and groundwater: an assessment of Gujarat’s pioneering Jyotirgram Scheme
Tube well irrigationWellsPumpsElectrificationFarmers attitudesShare croppingPovertyUser chargesRural economy
EVALUATION OF DAIRY AND CARCASS PERFORMANCES OF LESSER KNOWN GANG-FATEHPURI SHEEP OF UTTAR PRADESH
M.K. Verma*1, V.K. Singh1, J. Singh1, A. K. Verma2and Rajesh Kumar
Understanding the role of membrane cholesterol upon Epstein Barr virus infection in astroglial cells.
Background: EBV infection has long been postulated to trigger multiple sclerosis (MS) and anti-EBV antibodies showed a consistent presence in MS patients. Previous reports from our group have shown that the EBV infects different brain cells. Entry of the virus in neuronal cells is assisted by several host factors including membrane cholesterol. By using an inhibitor, methyl-β-cyclodextrin (MβCD), we evaluated the role of membrane cholesterol in EBV infection and pathogenesis.
Methodology: The membrane cholesterol depleted cells were infected with EBV and its latent genes expression were assessed. Further, EBV-mediated downstream signalling molecules namely STAT3, RIP, NF-kB and TNF-α levels was checked at protein level along with spatial (periphery and nucleus) and temporal changes in biomolecular fingerprints with Raman microspectroscopy (RS).
Results: Upon treatment with MβCD, lmp1 and lmp2a suggested significant downregulation compared to EBV infection. Downstream molecules like STAT3 and RIP, exhibited a decrease in protein levels temporally upon exposure to MβCD while NF-kB levels were found to be increased. Further, the intensity of the Raman spectra exhibited an increase in triglycerides and fatty acids in the cytoplasm of EBV-infected LN-229 cells compared to MβCD+EBV. Likewise, the Raman peak width of cholesterol, lipid and fatty acids were found to be reduced in EBV-infected samples indicates elevation in the cholesterol specific moieties. In contrast, an opposite pattern was observed in the nucleus. Moreover, the ingenuity pathway analysis revealed protein molecules such as VLDLR, MBP and APP that are associated with altered profile of cholesterol, fatty acids and triglycerides with infection-related CNS disorders.
Conclusion: Taken together, our results underline the important role of membrane cholesterol over EBV entry/pathogenesis in astroglia cells which further trigger/exacerbate virus-associated neuropathologies. These results likely to aid into the prognosis of neurological disease like MS
[Photograph 2012.201.B1370.0330]
Photograph used for a story in the Daily Oklahoman newspaper. Caption: "Marvin York Vo-tech Center students, from left, Greg Wiley, Felicia Archer and Rajesh Verma each receive a scholarship from the Oklahoma City Hotel-Motel Association.
Role of demographic and psychological factors on vaccine reluctance in Covid-19: A systematic review
Sweeping has no effect on renormalized turbulent viscosity
We perform renormalization group analysis (RG) of the Navier-Stokes equation in the presence of constant mean velocity field , and show that the renormalized viscosity is unaffected by , thus negating the ``sweeping effect", proposed by Kraichnan [Phys. Fluids {\bf 7}, 1723 (1964)] using random Galilean invariance. Using direct numerical simulation, we show that the correlation functions for and differ from each other, but the renormalized viscosity for the two cases are the same. Our numerical results are consistent with the RG calculations
Effectiveness of cognitive behavioural therapy for adults with depression and anxiety during COVID-19: A Systematic review of randomised controlled trials
Introduction: The COVID-19 pandemic has forced the administration of Cognitive Behavioural Therapy (CBT) either face-to-face or online. This systematic review aims to assess the effectiveness of CBT and Internet-Delivered CBT (iCBT) in treating depression and anxiety disorders during the COVID-19 outbreak.
Methods: Three independent reviewers searched the Web of Science, PubMed, Cochrane Library, and Clinical Trial Databases using specific search phrases. PubMed searches included “Cognitive Behavioural Therapy/Intervention” and “COVID-19” and “2019 Coronavirus Disease” or “2019-nCoV”, “internet-administered/internet-based cognitive behavioural therapy, CBT, cognitive behavioural treatment”. Two independent reviewers evaluated the risk of bias at the study level, with disagreements settled through discussion with other research team members. The study findings were reported as per the PRISMA guidelines.
Results: Thirty-one studies met the inclusion criteria, and 17 were randomised controlled trials. The studies demonstrated that CBT and iCBT effectively treated depression and anxiety disorders during the COVID-19 pandemic. However, a hybrid CBT modality was more beneficial from a long-term perspective.
Conclusion: The findings suggest that CBT and iCBT effectively treat depression and anxiety disorders during the COVID-19 pandemic. However, further research is needed to establish these interventions’ long-term effectiveness and identify the optimal mode of delivery for different population
A Unified Shell model for Buoyancy-Driven Turbulence
We construct a unified shell model for stably stratified and convective turbulence. Shell model simulation of stably stratified flow in turbulent regime exhibit Bolgiano-Obukhbov (BO) scaling in which the kinetic energy spectrum varies as . However, simulation of convective turbulence shows Kolmogorov's spectrum. These results are consistent with the direct numerical simulations of Kumar {\em et al.} [Phys. Rev. E {\bf 90}, 023016 (2014)]. We also observe a dual scaling ( and ) for a limited range of parameters in stably stratified flow
Energy transfers in small-scale and large-scale dynamos
We study energy transfers during magnetic energy growth in small-scale and large-scale dynamos. We perform direct numerical simulations for magnetic Prandtl number Pm =20 and 0.2 in a periodic box on 1024^3 grid. Energy fluxes and shell-to-shell energy transfers indicate that in small-scale dynamo for Pm =20, the magnetic energy growth takes place due to a non-local energy transfer from large-scale velocity field to small-scale magnetic field. On the other hand, in large-scale dynamo for Pm =0.2, local energy transfers from large-scale velocity field to large-scale magnetic field takes place
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