58 research outputs found
FRUIT CHARACTERISTICS OF LITCHI GENOTYPES UNDER CHOTANAGPUR CONDITIONS
No full textThe litchi (Litchi chinensis Sonn.) is an important evergreen sub-tropical fruit tree specific
to climatic requirement for 'its production. Litchi possesses a narrow genetic base for various agrom
ophol ogical traits. Continuous vegetative propagation of commercial cultivars has further
narrowed down the genetic base resulting in the .restricted period of availability of fruits in the market.
Cultivars have been classified on the basis of economic traits in China and on the basis of growth
and flowering pattern in India (Arora et al. 1996; Singh, 1998). Rai and Vishal Nath (2001) reported
a total of 51 genotypes being augmented from different litchi growing regions and maintained at
HARP, Ranchi. Xuequin (1995) reported 20-25 main litchi types possessing characters of larger fruit size,
small stone, thick and free aril of good quality with good flavor having canning quality from south
China. However, cultivar synonymy does exit due to the insufficient information on i:;haracterization
for different fruit morphological traits and delineation of the characters in its original name. Only few
cultivars and be distinguished based on their fruits characters and maturity period. which creates confusion in identifying the suitable cultivar for any specific region. Keeping this in view, a study was carried out to characterize the different litchi genotypes on the basis of physico-chemical characteristics of fruit under the Chotanagpur plateau region of eastern IndiaUtchi has narrow genetic base owing to greater use of asexual propagation. Cultivar
synonymy on the basis of local nomenclature causes confusion in identifying a genotype
for any specific purpose. There fore, 17 genotypes under study have been characterized
on the basis of fruit shape index (FSI), specific gravity, seed shape index (SS/), flatness of
seed, number of protuberances/cm' and other physico-chemica/ characters of fruit. The
cultivars China, Purbi and Bombaiya-11 found to have elongated fruit shape whereas
Bedana, Swarna Roopa, Trikolia and Shahi posses roundish fruit shape. Regarding pulp
%, the cultivars Bedana, D. Rose, Late Bedana, Green and Rose Scented has the high
values. The cultivars Purbi, China, Swarna Roopa and Dehradun has thick peel. Widely
spread protuberances was noticed in cultivars Swarna Roopa, Dehradun and Bedana.
Bedana, Late Bed;ma and Swarna Roopa had smaller seeds. The cul/ivars Bombaiya-1,
Bombaiya-11, Late Bedana, CHES-II, China and Purbi had slender seeds while Deshi,
Bombaiya-1 and Late Bedana has flat seeds.Not Availabl
Guanidino-aryl substituted enol lactones: Selective and potent mechanism-based inhibitors of trypsin-like serine proteases
No full textTwo classes of valero enol lactones were synthesized and examined as potential inhibitors of trypsin-like serine proteases. The first class of protio and iodo enol lactones had either a 4-guanidino phenyl substituent (3-(4-guanidinophenyl)-6-methylidene tetrahydro-2-pyranone (1) and 3-(4-guanidinophenyl)-6-(E)-iodomethylidene tetrahydro-2-pyranone (2)) or a 4-guanidinomethyl phenyl substituent (3-(4-guanidinomethylphenyl)-6-methylidene tetrahydro-2-pyranone (3) and 3-(4-guanidinomethylphenyl)-6-(E)-iodomethylidene tetrahydro-2-pyranone (4)) at the -position. The -aryl substituted system included the 4-guanidino phenyl substituted protio and iodo enol lactones 4-(4-guanidinophenyl)-6-(methylidene) tetrahydro-2-pyranone (5) and 4-(4-guanidinophenyl)-6-(E)-iodomethylidene tetrahydro-2-pyranone (6), as well as the corresponding -benzamido substituted analogs (3R*,4R*) 3-benzamido-4-(guanidinophenyl)-6-methylidene tetrahydro-2-pyranone (7) and (3R*,4R*) 3-benzamido-4-(4-guanidinophenyl)-6(E)-iodomethylidene tetrahydro-2-pyranone (8).The lactones were tested for inhibitory activity against some trypsin-like enzymes, namely tyypsin, urokinase, tissue plasminogen activator (t-PA), plasmin and thrombin, as well as -chymotyypsin and human neutrophil elastase (HNE). The -(guanidino phenyl) substituted iodo lactone 2 was a suicide substrate of urokinase, plasmin, t-PA, thrombin and -chymotrypsin, with an exceptionally high specificity for the former two enzymes. The guanidinomethyl phenyl substituted iodo lactone 4 was a suicide substrate of all the trypsin-like enzymes tested, exhibiting exceptionally high specificity in its inhibition of trypsin and urokinase. The corresponding protio lactone 3 was an alternate substrate inhibitor of urokinase and thrombin, its potency being attributed to moderately stable acyl enzyme intermediates. Among the -aryl substituted lactones, no new suicide substrates for trypsin-like enzymes were found. The lactones 5 and 6 were alternate substrate inhibitors, selective for the trypsin-like enzymes. The iodo lactone 8 was a potent transient inactivator of trypsin and urokinase; in addition, it was a very selective and effective suicide substrate of -chymotrypsin.In general, the guanidino-aryl substituted enol lactones showed selectivity and superior specificities for trypsin-like enzymes, over -chymotrypsin and HNE. In addition, there was some selectivity within the class of trypsin-like enzymes. The -aryl substituted iodo lactones were suicide substrates and the -aryl substituted systems were potent alternate substrate inhibitors of some of the trypsin-like enzymes.Made available in DSpace on 2011-05-07T13:36:05Z (GMT). No. of bitstreams: 2
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Sensory Profiling and Positioning of Market Samples of Potato Chips
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Establishment of Reference Intervals of Serum Hepatic Enzymes in Tertiary Care Hospital: A Pilot Study
No full textABSTRACT
Introduction
Reference intervals are the most common decision-making tools for the interpretation of various biochemical reports. Age, sex, ethnicity, diet, physical, and socioeconomic conditions affect the physiology of population. Hence, it is necessary to set up the reference values that are applicable to a specific population rather than using the reference values established for other population-based studies or from the literature provided by the reagent kit manufacturers.
Aims and objectives
To establish the reference intervals of serum hepatic enzymes in tertiary care hospital.
Materials and methods
Hospital-based cross-sectional study was done involving 200 subjects. The subjects were randomly selected from the population, which included medical students, health professionals, and those attending different outpatient departments and health camps organized by the hospital for general checkups under health plan scheme. Serum alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) were estimated by the International Federation of Clinical Chemistry-recommended kinetic method and GGT by enzymatic colorimetric method. To obtain reference interval, 97.5th percentile and 2.5th percentile were used.
Results
The results for serum AST and GGT were found to be statistically significant. Hence separate reference intervals for both male and female were set up. Generalized reference intervals were established for serum ALT and ALP levels.
Conclusion
The present study revealed a significant difference in the reference intervals between males and females.
How to cite this article
Rai PS, Shetty S, Patil P, Bhandary R. Establishment of Reference Intervals of Serum Hepatic Enzymes in Tertiary Care Hospital: A Pilot Study. Indian J Med Biochem 2017;21(1):22-24.
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Contribution of protein phosphorylation to binding-induced folding of the SLBP–histone mRNA complex probed by phosphorus-31 NMR
No full textAbstractPhosphorus-31 (31P) NMR can be used to characterize the structure and dynamics of phosphorylated proteins. Here, I use 31P NMR to report on the chemical nature of a phosphothreonine that lies in the RNA binding domain of SLBP (stem-loop binding protein). SLBP is an intrinsically disordered protein and phosphorylation at this threonine promotes the assembly of the SLBP–RNA complex. The data show that the 31P chemical shift can be a good spectroscopic probe for phosphate-coupled folding and binding processes in intrinsically disordered proteins, particularly where the phosphate exhibits torsional strain and is involved in a network of hydrogen-bonding interactions
Fundamental investigation of bio-surfactants-assisted harvesting strategy for microalgae
No full textThe lack of energy-sufficient harvesting technologies has dramatically impeded the commercialization of microalgae-derived bio-products. To address this challenge, a foam flotation harvesting approach using bio-surfactants has been previously developed for microalgae. However, most studies have applied chemical surfactants in the foam flotation, which is in opposition to the concept of sustainability. Thus, in this study, two bio-surfactants including rhamnolipid and Bovine Serum Albumin (BSA) were applied in foam flotation-assisted harvesting for Chlorella vulgaris. Initially, the ability of foam formation and foam stability in different microalgal culture media including distilled water, MiracleGro™, and Bold's Basal Medium (BBM) were evaluated. Following this, the microalgal cell adhesion mechanism was elucidated using FTIR analysis, zeta potential, and conductivity. The results showed that a higher degree of foam stability was observed when using BSA as the bio-surfactant than rhamnolipids. No big difference in the zeta potential was observed for BSA in all tested culture media, and the value of zeta potential was approx. 20 mV whereas, a difference was observed between rhamnolipid solution and rhamnolipid in culture media at all tested conditions. On the contrary, in the conductivity analysis, the use of rhamnolipids led to a higher conductivity at all investigated conditions compared to BSA. FTIR analysis suggested that the addition of either rhamnolipids or BSA did not affect the functionality. Overall, this fundamental study regarding the bio-surfactant-assisted foam flotation harvesting strategy for microalgae lays the foundation for process development.NSERCUniversity of Prince Edward Island (UPEI
Reductions and radical cyclizations of aryl and alkyl bromides mediated by NaBH4 in aqueous base
No full textEffect of conformational mobility and hydrogen-bonding interactions on the selectivity of some guanidinoaryl-substituted mechanism-based inhibitors of trypsin-like serine proteases
No full textCharacterization and determination of the solution state conformation of a Thirteen residue peptide
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
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