43,063 research outputs found
Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)
No full textIn an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola
[Memo from Lieutenant Colonel M. F. Hass, Civil Affairs Division, with amendments to an evacuation proposal]
No full textA memorandum sent form Lieutenant General M. F. Hass, Civil Affairs Division, which has two corrections from a an evacuation proposal originally sent on May 13, 1942. The correction changes the destination to the Merced Assembly Center.The War Relocation Authority (WRA), together with the Wartime Civil Control Administration (WCCA), the Civil Affairs Division (CAD) and the Office of the Commanding General (OFG) of the Western Defense Command (WDC) operated together to segregate and house some 110,000 men women and children from 1942 to 1945. The collection contains documents and photographs relating to the establishment and administrative workings of the (WDC), the (WRA) and the (WCCA) for the year 1942
Corrigendum to “Presence and function of kisspeptin/KISS1R system in swine ovarian follicles” (Theriogenology (2018) 115 (1–8), (S0093691X1830147X), (10.1016/j.theriogenology.2018.04.006))
No full textThe authors regret the following changes to the author group G. Basinia, F. Grassellia, S. Bussolatia, R. Ciccimarraa, M. Maranesib, A. Bufalarib, C. Dall'Agliob, F. Parilloc,#, M. Zeranib,c,*. a Dipartimento di Scienze Mediche Veterinarie, Università di Parma, 43126 Parma, Italy. b Dipartimento di Medicina Veterinaria, Università di Perugia, 06126 Perugia Italy. c Scuola di Bioscienze e Medicina Veterinaria, Università di Camerino, 62024 Matelica Italy. # Deceased. * Corresponding author: tel.: +39 0755857642; fax +39 0755857654. E-mail address: [email protected] (M. Zerani). And to the acknowledgements and figures
[Memo from Lieutenant Colonel M. F. Hass, Civil Affairs Division, with amendments to an evacuation proposal]
No full textA memorandum sent form Lieutenant General M. F. Hass, Civil Affairs Division, which has two corrections from a an evacuation proposal originally sent on May 11, 1942. The first correction changes the number of evacuees to 275 people, and the second correction changes the destination to Tanforan Assembly Center.The War Relocation Authority (WRA), together with the Wartime Civil Control Administration (WCCA), the Civil Affairs Division (CAD) and the Office of the Commanding General (OFG) of the Western Defense Command (WDC) operated together to segregate and house some 110,000 men women and children from 1942 to 1945. The collection contains documents and photographs relating to the establishment and administrative workings of the (WDC), the (WRA) and the (WCCA) for the year 1942
An epigenetic view of B-cell disorders
No full textB-cell development is a multistep process sustained by a highly coordinated transcriptional network under the control of a limited set of transcription factors. Epigenetic mechanisms, including DNA methylation, histone posttranslational modifications and microRNAs act in concert with transcription factors to promote lineage commitment, define and sustain cell identity and establish heritable cell-type- and stage-specific gene expression profiles. Epigenetic modifiers have recently emerged as key regulators of B-cell development and activation. Central to B-cell-mediated immunity are germinal centers, transient structures formed in secondary lymphoid organs where antigen-specific B cells undergo intense proliferation, immunoglobulin somatic hypermutation and isotype switching, to generate ultimately long-lived memory B cells and terminally differentiated plasma cells expressing high-affinity antibodies. Deregulation of one or more epigenetic axes represents a common feature of several B-cell disorders arising from germinal center B cells, including autoimmunity and lymphoma. Moreover, the hijacking of epigenetic determinants is central to the ability of the B-lymphotropic Epstein-Barr virus (EBV) to establish, via the germinal center reaction, life-long latency and occasionally contribute to malignant B-cell transformation. In the light of recent findings, this review will discuss the relevance of epigenetic deregulation in the pathogenesis of B-cell diseases. Understanding how specific epigenetic alterations contribute to the development of lymphomas, autoimmunity and EBV-associated disorders is instrumental to develop novel therapeutic interventions for the cure of these often fatal pathologies
[Memo from Lietnenant Colonel M. F. Hass, Civil Affairs Division, regarding the destination for Exclusion Order No. 98]
No full textA one page memo from Lieutenant Colonel M. F. Hass, Civil Affairs Division, that declares the destination for evacuees affected by Exclusion Order No. 98. The evacuees from all three movements were sent to the Portaln Assembly Center in Oregon.The War Relocation Authority (WRA), together with the Wartime Civil Control Administration (WCCA), the Civil Affairs Division (CAD) and the Office of the Commanding General (OFG) of the Western Defense Command (WDC) operated together to segregate and house some 110,000 men women and children from 1942 to 1945. The collection contains documents and photographs relating to the establishment and administrative workings of the (WDC), the (WRA) and the (WCCA) for the year 1942
Nicotinic acetylcholine receptors in rat forebrain that bind ¹⁸F-nifene: relating PET imaging, autoradiography, and behavior
No full textNicotinic acetylcholine receptors (nAChRs) in the brain are important for cognitive function; however, their specific role in relevant brain regions remains unclear. In this study, we used the novel compound ¹⁸F-nifene to examine the distribution of nAChRs in the rat forebrain, and for individual animals related the results to behavioral performance on an auditory-cognitive task. We first show negligible binding of ¹⁸F-nifene in mice lacking the β2 nAChR subunit, consistent with previous findings that ¹⁸F-nifene binds to α4β2* nAChRs. We then examined the distribution of ¹⁸F-nifene in rat using three methods: in vivo PET, ex vivo PET and autoradiography. Generally, ¹⁸F-nifene labeled forebrain regions known to contain nAChRs, and the three methods produced similar relative binding among regions. Importantly, ¹⁸F-nifene also labeled some white matter (myelinated axon) tracts, most prominently in the temporal subcortical region that contains the auditory thalamocortical pathway. Finally, we related ¹⁸F-nifene binding in several forebrain regions to each animal's performance on an auditory-cued, active avoidance task. The strongest correlations with performance after 14 days training were found for ¹⁸F-nifene binding in the temporal subcortical white matter, subiculum, and medial frontal cortex (correlation coefficients, r > 0.8); there was no correlation with binding in the auditory thalamus or auditory cortex. These findings suggest that individual performance is linked to nicotinic functions in specific brain regions, and further support a role for nAChRs in sensory-cognitive function.Peer reviewedAuthor's Manuscript is also available open access in PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292694.This is the peer reviewed version of the following article: Bieszczad, K. M., Kant, R., Constantinescu, C. C., Pandey, S. K., Kawai, H. D., Metherate, R., Weinberger, N. M. and Mukherjee, J. (2012), Nicotinic acetylcholine receptors in rat forebrain that bind 18F-nifene: Relating PET imaging, autoradiography, and behavior. Synapse, 66: 418–434. doi: 10.1002/syn.21530, which has been published in final form at http://dx.doi.org/10.1002/syn.21530. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving
Planopusa semenovi Koretsky & Rahmat 2021, sp. n.
No full textPlanopusa semenovi, sp. n. (figs 2–5; tables 1 –3) H o l o t y p e. NMNHU-P 64-709, rostral part of the skull with I3, C, P1, P2, and isolated P4 and M1; P3 is absent (fig. 2). Collected by Yu. A. Semenov in 1995 and stored in the NMNHPM. Type locality. Grytsiv, Shepetivskyi District Khmelnytskyi Region, Western Ukraine, karst deposits in limestone quarry on the right bank of Chomora River, 3 km west of village of Grytsiv; 49°58ˈ 05.2 N 27°10ˈ03 E (reef zone). F o r m a t i o n a n d A g e. Middle Sarmatian, middle-late Miocene; MN 9, likely in the interval from 11.146 –11.056 Ma. Diagnosis. Small seal with extremely short rostrum (table 1), differing from all other fossil and extant phocines by: 1) flattened palatal process of maxilla; 2) P4 longer than M1; 3) alveoli form a straight line; 4) wider rostrum across canines compared to other small Phocinae (but narrower than in Monachopsis pontica). Description. The partial skull likely belongs to an adult, based on the fused sutures. However, teeth are not worn, characteristic for sub-adults. The maxilla has a very short convexity over P1 and convexity started over P2. The incisive bone is partially broken and palatal process of the maxilla is flattened from the level of the anterior alveolus of P2. The large grooves (fissura palatine) from anterior palatal foramina are directed towards the incisors (as in Enhydra lutris, fig. 3), in contrast to the condition stated by Wozencraft (1989) for other phocids, but similar to seals of the subfamily Devinophocinae (Koretsky and Holec, 2002; Koretsky and Rahmat, 2015). The concave palatine is wider (18.0 mm) between canines, similar to that in Devinophoca emryi (Koretsky and Rahmat, 2015). The hard palate is half the length of the smallsub-adult of Pusa caspica. Palatal grooves are shallow, but present without the posterior palatal foramen. Part of the palatal bone is missing. Posterior border of the anterior palatal foramen is situated at the level of P1 (in contrast to that in Pusa caspica where it is between C and P1). In coronal view, the space between the posterior border of the anterior palatal foramen and the anterior border for the choanae is 7.5 mm (11.0 mm in Pusa caspica). The lingual alveolar margins of canines and incisors are at the same level as those of the cheek teeth (as in D. emryi), but alveolar margins of C and P1 are compressed towards the midline. From the anterior palatal foramina to the level of P2, the palatine is flat. A deep, antero-posteriorly aligned groove (sulcus palatinus) is present posterior to P2, characterized as a derived condition among phocids according to Wyss and Flynn (1993) and in contrast to D. emryi. Maxillary teeth: All teeth are very small with double roots (except C, P1). The incisors are arranged in a straight line. The roots of alveoli I3 are larger than I2, which in turn is larger than I1. The I3 crown is preserved with a small cingulum on the lingual side, round in cross-section. Cingula present only on lingual sides of the crown and do not extend the buccal (labial) side (in contrast to Devinophoca) (fig. 2). Canines project ventrally, slightly worn (possibly sub-adult), but the anterior surface in both canines is worn or due to overbite with grinding of the lower canine (figs 2, 3). The diastema is absent between C and P1, which is located obliquely to the tooth row. The snout is shortened, but the canines are relatively large compared to the length of the snout and other teeth, supporting the overbite hypothesis where the lower canine wears the upper, similar to those in Gulo gulo (wolverine) (IZUAN 896, from the Archangelsk area). Diastemata between postcanine teeth are absent. All alveoli are rounded and the posterior roots of P2, P4, and M1 are larger than anterior roots. Tooth crowns are not worn. The large paraconid (central cusp) is turned caudally, with one small anterior cusp and a posterior cusp that is larger and positioned higher. The third cusp is placed on the basal cingulum, located caudally to the posterior cusp, and it is much smaller than other cusps (especially smaller on M1). The P1 has a single root, oval in cross-section, almost intact (similar to Praepusa). Its crown is 5.0 mm long (table 2), with a conical (triangular) central cusp and cuspidate lingual cingulum bearing diminutive two posterior cusps (in contrast to D. emryi). Cinguli on P2, P4, and M1 are parallel to the lower enamel margin. On P2, P4, and M1, the gum line is parallel to the margin of the dentary. The complete crowns on postcanine teeth (except P1) are irregularly shaped in occlusal view (in contrast to D. emryi). The P1 is flattened disto-lingually on its lingual side. The cingulum, bearing minute cuspules, encircles the crown on the lingual side of the P1. The P2-M1 crowns are triangular in occlusal view and slightly worn. The P2-M1 teeth have two roots, both round in cross-section. The posterior root on P2 is wider and much larger than the anterior alveolus. The P2 is situated in parallel to the tooth row. The P2 crown has a very prominent lingual cingulum with a minute anterior cingular cusp and slightly larger than two posterior cusps. The cingulum on the labial side extends around the entire tooth (in contrast to D. emryi) with carinae (sharp tooth edges) similar to those observed in Monachinae (Amson and Muizon, 2014). The buccal side of the P4 is straight. This tooth has the widest crown base. Posterior root is larger than anterior one, with one anterior cusp, two posterior cusps, and an additional cusp on the lingual side of the cingulum. The crown is triangular in occlusal view. The P4 is larger than M1. The M1 is very small (5.5 mm long and 3.5 mm wide) with two fused roots. The crown is triangular in occlusal view, similar to other postcanines, but much smaller. The anterior cusp is absent, but there is a single posterior cusp and a gracile cingular posterior cusp. Cingulum on the labial side is absent; the tip of the tooth is turned caudally. Cingula are located transversely only on the lingual sides of the crown, not extending the labial (buccal) side (in contrast to those in Devinophoca). C o m p a r i s o n s w i t h s m a l l - s i z e d r e p r e s e n t a t i v e s o f t h e f a m i l y P h o c i d a ePublished as part of Koretsky, I. A. & Rahmat, S. J., 2021, Unique Short-Faced Miocene Seal Discovered In Grytsiv (Ukraine), pp. 143-154 in Zoodiversity 55 (2) on pages 145-149, DOI: 10.15407/zoo2021.02.143, http://zenodo.org/record/645584
[Memo from Lieutenant Colonel M. F. Hass, Civil Affairs Division, about the evacuation schedule from Sacramento County]
No full textA one page memo from Lieutenant Colonel M. F. Hass, Civil Affairs Division, with an adjusted evacuation schedule related to Exclusion Order No. 93. The memo states that the adjusted schedule was due to requests from Japanese families to be reunited in the Sacramento Assembly Center. The evacuation dates are from May 27 to May 29, 1942.The War Relocation Authority (WRA), together with the Wartime Civil Control Administration (WCCA), the Civil Affairs Division (CAD) and the Office of the Commanding General (OFG) of the Western Defense Command (WDC) operated together to segregate and house some 110,000 men women and children from 1942 to 1945. The collection contains documents and photographs relating to the establishment and administrative workings of the (WDC), the (WRA) and the (WCCA) for the year 1942
[Memo from Lieutenant Colonel M. F. Hass, Civil Affairs Division, regarding the evaucation schedule for Exclusion Order No. 92]
No full textA one page memo from Lieutenant Colonel M. F. Hass, Civil Affairs Division, with an adjusted evacuation schedule related to Exclusion Order No. 93. Due to over-registration in the Sacramento area, the evacuation schedule was revised. The memo includes the number of people to be evacuated between May 27 and May 29, 1942.The War Relocation Authority (WRA), together with the Wartime Civil Control Administration (WCCA), the Civil Affairs Division (CAD) and the Office of the Commanding General (OFG) of the Western Defense Command (WDC) operated together to segregate and house some 110,000 men women and children from 1942 to 1945. The collection contains documents and photographs relating to the establishment and administrative workings of the (WDC), the (WRA) and the (WCCA) for the year 1942
- …
