102,739 research outputs found

    Solvency II: cambiano le regole di fare assicurazione

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    Il presente contributo intende offrire una panoramica dei principali cambiamenti nella concreta operatività di una compagnia di assicurazione alla luce della recente introduzione della nuova cornice regolamentare "Solvency II".This chapter aims to provide an overview of the main changes in the management of insurance companies in the light of the recent introduction of the new regulatory framework "Solvency II"

    Multimodal-lifestyle interventions for overweight and obese children: a summary of results

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    t: The increase of obesity and decline of fitness during childhood highlight the need for suitable interventions, designed to increase physical activity in children and adolescents. This paper aims to describe and identify the characteristics of three childhood obesity programs conducted in pediatric primary care setting and/or in school environment. Participants were overweight and obese boys and girls, aged 8 to 12 years. Children were assessed before and after the interventions with respect to body composition, physical activity, physical fitness, body image, perceived physical ability, enjoyment of physical activity, health related quality of life, and dietary habits. After treatments, overweight and obese children reported improvements in the body mass index, percent body fat, and in almost all health-related fitness tests. Psychosocial health related quality of life, body image, perception of physical ability, and physical activity enjoyment also improved at the end of the programs. For dietary habits, participants reported reductions in total and commercial food caloric intakes, with higher protein and lower fat consumptions from pre- to post-intervention. Results could have methodological implications for tailoring interventions to the needs of obese children. Findings encourage the adoption of a comprehensive approach focused on nutritional education and structured fun-based skill-learning physical activity

    XXXVI National Meeting in Medicinal Chemistry

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    Several studies showed that an uncontrolled reactive oxygen species (ROS) production can cause cellular damage and death also leading to many diseases such as atherosclerosis, arthritis, diabetes, cancer, and inflammatory bowel disease (IBD). In order to maintain the redox homeostasis, ROS are neutralized by the endogenous enzymatic and non-enzymatic antioxidant systems. An imbalance in these mechanisms lead to excessive levels of ROS and subsequently the oxidative stress.1 Therefore, dietary antioxidants can supplement the antioxidant system and help to reduce the degenerative oxidative damage. Vegetable matrices represent important sources of several classes of antioxidant compounds such as polyphenols and bioactive peptides, which are often used as ingredients for developing functional foods and nutraceutical products.2 Among them, the potatoes (Solanum tuberosum) are of particular interest because, in terms of production, potato is the second largest protein-supplying crop per hectare grown, and in terms of consumption since it has been a staple food in many traditional diets of the Western world. To date, more than half of all potatoes consumed are chips, fried and roast potatoes or processed potato products, especially among older children and young adults. Therefore, potatoes represent a contradictory food because they contain macronutrients such as proteins and fibers able to exert beneficial effects on human health. On the other hand, the frequent consumption of fried potatoes appears to be associated with developing obesity, diabetes, and cardiovascular disease due to their large starch content and high glycemic index.3 In addition, potatoes provide other important micronutrients such as vitamins and organic acids, which are all associated with a decreased risk of morbidity and mortality.4 For these reasons, in order to maintain the beneficial properties of potatoes and decrease the higher intakes of trans fatty acids, oxidized lipids, acrolein, acrylamide, furan, and glycidamide of fried potatoes, in this work we have investigated the antioxidant properties of dehydrated potatoes. In detail, an on-line HPLC- -diphenyl-1- polyphenol was developed. To identify bioactive peptides, a simulated gastrointestinal digestion was performed. Peptide extract was tested on intestinal epithelial cells (IEC-6) under inflammatory condition. Our results demonstrate that the peptide fraction was able to significantly inhibit pro-inflammatory mediators such as inducible nitric oxide synthase (iNOS) and cycloxygenase-2 (COX-2) expression and oxidative stress markers such as nitrotyrosine formation and ROS release. The results demonstrate a potential use of dehydrated potatoes in the prevention the inflammatory and oxidative stress state at the intestinal level

    Max Horn SAT and the minimum cut problem in directed hypergraphs

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    In this paper we consider the Maximum Horn Satisfiability problem, which is reduced to the problem of finding a minimum cardinality cut on a directed hypergraph. For the latter problem, we propose different IP formulations, related to three different defnitions of hyperpath weight. We investigate the properties of their linear relaxations, showing that they define a hierarchy. The weakest relaxation is shown to be equivalent to the relaxation of a well known IP formulation of Max Horn SAT, and to a max-flow problem on hypergraphs. The tightest relaxation, which is a disjunctive programming problem, is shown to have integer optimum. The intermediate relaxation consists in a set covering problem with a possible exponential number of constraints. This latter relaxation provides an approximation of the convex hull of the integer solutions which, as proven by the experimental results given, is much tighter than the one known in the literature

    A tenant-driven slicing enforcement scheme based on Pervasive Intelligence in the Radio Access Network

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    In Beyond 5G mobile networks, the network slicing paradigm offers the possibility of sharing the network infrastructure among different tenants: the tenant declares communication service requirements and the Infrastructure Provider configures (potentially on-demand) the corresponding network slice instances. The management of network slicing in the core network has been deeply investigated in the current scientific literature. On the contrary, handling network slicing in the Radio Access Network still represents an open and very challenging research topic, mostly due to the unpredictable variability of the wireless channel, network dynamics and heterogeneity, slice isolation, as well as different Quality of Service requirements of various services. In order to achieve an important step forward in this direction, this paper proposes a tenant-driven Radio Access Network slicing enforcement scheme based on Pervasive Intelligence. The proposed approach grounds its roots in the Pay for What You Get paradigm: it promises to avoid the radio resources over-provisioning while saving bandwidth. To achieve these goals, Artificial Intelligence mechanisms are innovatively and pervasively integrated into some key functionalities of both Infrastructure Provider and tenants. On the one hand, the Infrastructure Provider exploits a Deep Learning scheme (i.e., convolutional autoencoder) to compress the information on network resources and connectivity and share the actual (but hidden through compression) network status with the tenants. On the other hand, each tenant implements a Deep Reinforcement Learning algorithm (i.e., Deep Deterministic Policy Gradient) to dynamically adapt bandwidth requests according to its own users’ requirements. The outcomes of this algorithm are then used by the Infrastructure Provider to effectively enforce network slicing at the Radio Access Network level. Computer simulations investigate the proposed approach in a realistic scenario, which jointly embraces enhanced Mobile BroadBand, Advanced Driver Assistant Systems, and best-effort applications. Obtained results demonstrate the effectiveness of the proposal against conventional resource allocation methods
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