17 research outputs found

    Unusual location of recurrent mantle cell lymphoma on fluorodeoxyglucose-positron emission tomography despite complete metabolic resolution of previous sites of disease

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    This case report presents a patient with recurrent pleomorphic mantle cell lymphoma (MCL), which is a relatively rare but aggressive type of lymphoma. A positron emission tomography/computed tomography scan performed to assess treatment response demonstrated a complete metabolic response in the sites of primary disease while also revealing new subcutaneous lesions, which were biopsy-proven recurrent disease. This case illustrates the importance of the different biological behavior of MCL, whereby new sites of metabolically active lesions can represent recurrent disease, even though there is a complete metabolic response at sites of primary disease

    Impact of 18F-FDG PET/CT on treatment of patients with differentiated thyroid carcinoma, negative 131I whole body scan and elevated serum thyroglobulin

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    Objective(s):18 F-FDG PET/CT is increasingly performed in patients with differentiated thyroid cancer. The aim of this study was to assess the clinical impact of18 F-FDG PET/CT on the management of patients with differentiated thyroid carcinoma who had elevated serum thyroglobulin (Tg) and negative131 I whole body scan (WBS) . Methods: 67 patients with differentiated thyroid carcinoma were included in this study. The findings of18 F-FDG PET/CT imaging were compared with histo-pathology, follow up imaging, or clinical follow-up results. The diagnostic accuracy of18 F-FDG PET/CT was evaluated for the entire patient group and for those patients with stimulated serum thyroglobulin levels of less than 5, 5–10, and more than 10 pmol/L as well as for local recurrences and metastases sites. The impact of 18F-FDG PET/CT on therapeutic management was also evaluated . Results: 30/67 patients had positive findings on18 F-FDG PET/CT; 28 were true-positive and 2 were false-positive.18 F-FDG PET/CT results were true-negative in 36 patients and false-negative in 1 patient. The overall sensitivity, specificity, accuracy, PPV and NPV of18 F-FDG PET/CT were, 96.5%, 94.5%, 95.5%, 93.3%, and 97.2% respectively. Positive18F-FDG PET/CT findings were directly correlated with stimulated serum thyroglobulin levels, 7.1% had Tg between 5–10, and 92.9% had Tg greater than 10 pmol/L.18 F-FDG PET/CT had a high or moderate impact on treatment management in 28 (41.8%) of patients. Conclusion:18 F-FDG PET/CT is able to improve diagnostic accuracy and have management impact in a therapeutically relevant way in patients with differentiated thyroid carcinoma who present with rising thyroglobulin level, negative131 I WBS, and clinical suspicion of recurrent disease

    Flourine-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Imaging of Peritoneal Carcinomatosis in Lung Cancer: A Case Study

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    Lung cancer with peritoneal carcinomatosis (PC) is a rare disease presentation. The presence of peritoneal disease is a sign of poor prognosis and is hard to diagnose. Flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) is becoming more clinically significant in the management of patients with PC. A 60-year-old male presented with nonsmall cell lung cancer (NSCLC) and later showed signs of peritoneal disease on 18 F-FDG PET/CT imaging, which subsequently lead to the diagnoses of PC with histopathology from peritoneal biopsy. The patient showed an excellent initial response to their NSCLC treatment but later presented with PC that was shown by FDG-avid ascites and a soft tissue mass in the pelvic area. The abdominal-pelvic lesions were confirmed cytologically to be peritoneal metastatic disease. 18 F-FDG PET/CT demonstrated value in preoperatively directing biopsy for diagnosing PC in this case of NSCLC. Further, 18 F-FDG PET/CT was useful in the monitoring of disease progression and thus influenced management in this case of NSCLC with PC, which is often challenging to detect and manage

    Effect of blood glucose level on standardized uptake value (SUV) in F-18- FDG PET-scan : a systematic review and meta-analysis of 20,807 individual SUV measurements

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    Objectives To evaluate the effect of pre-scan blood glucose levels (BGL) on standardized uptake value (SUV) in F-18-FDG-PET scan. Methods A literature review was performed in the MEDLINE, Embase, and Cochrane library databases. Multivariate regression analysis was performed on individual datum to investigate the correlation of BGL with SUVmax and SUVmean adjusting for sex, age, body mass index (BMI), diabetes mellitus diagnosis, F-18-FDG injected dose, and time interval. The ANOVA test was done to evaluate differences in SUVmax or SUVmean among five different BGL groups (200 mg/dl). Results Individual data for a total of 20,807 SUVmax and SUVmean measurements from 29 studies with 8380 patients was included in the analysis. Increased BGL is significantly correlated with decreased SUVmax and SUVmean in brain (p <0.001, p <0.001,) and muscle (p <0.001, p <0.001) and increased SUVmax and SUVmean in liver (p = 0.001, p = 0004) and blood pool (p=0.008, p200 mg/dl had significantly lower SUVmax. Conclusion If BGL is lower than 200mg/dl no interventions are needed for lowering BGL, unless the liver is the organ of interest. Future studies are needed to evaluate sensitivity and specificity of FDG-PET scan in diagnosis of malignant lesions in hyperglycemia.Peer reviewe

    UA-R-GC-1914-01-01-1956-09-01_Page-079

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    1. 4278 -- THE EDUCATIONAL PROGRAM: The report of the Committee in Interim Educational Program was read and discussed, The following decisions wort: reached: A - Recommendations rc. Tcuor y Studies, The Council decided that, for the present time, we should experiment with a relatively small group of students Accordingly, starting next Monday December 3, the Library will be open to serve the senior students working on their projects (about 110) the students remaining_ in Hill House (14) and four research students at S.O.S. Senior students trill bo allowed to meet with their advisers in their offices; rcassignmc nt of temporary advisers will also be made upon request submitted to Dr. .Pair Botor. B , Recommendations for carrying tlzrouph the work of the two semesters of this y ear b ~he Cōunci 1 acccptc cI the r. opqrt of the Committee as a sc:t of working principles, C Penn Hollcnba ch's letter re tllc Policy and Pro gr m of thiwr. Dr. Hollenbach' s lc:t tt r to Pr .A mix' Boktor was received, read and discussed. His comments and rccol.imendatior:cs will be taken into consideration. 1. 4279 - LDJOURLIIENT: The meeting adjourned at, 10:45 a,m, Neat meeting will bc: held next Nednc sday, December 5 at 9:00 am, Michel dchba. Pro-tc,mporo Secretary. WIVL;-'SITY COUPCIL December 5, 1956 - 9:00 A.M. 1. 4280 - PRESENT: Dr. Boktor (chairman), ?)r. Laila H^.mamsy, Dr. Husaini, i4r. Manucher, 4r. G1 ^hba. The meeting vas opened with a silent prayer. 1. 4281 - MMINUTES: Minutes of Pc.cembcr 1 were:, read and accepted as corrected. 1. 4282 - REQUEST FOR RETURN OF D). Boktor repertcd that the request for. the GETJEVL GROUP: return of Di. Ilollcnbacli and the remaining five Faculty members from Geneva had been denied by Washington, and that Dr. i''ïcLain had asked ì'ir. Culbertson to follow the matter further with the Lr ncrican author. Lti_c.s. Since the situation in Egypt has remarkably improved since the date of the first request, members of the Council recommends that we ask îr, Culbcrtson to got in touch with the American Pe:.p.artment of State for the return of the entire Geneva F-' culty, rather than restrict his application to thy: return of the first group of six. 1, 4283 - REOPENING OF SCHOOL: i ri official from the Ministry of Education reported last Monday December 3, that the military author5 tic. s had been askod to withdraw their soldiers from the schools startinr_ tomorrow, Thursday December 6. It was also indicated that Eny'oiian soldiers have already withdrawn from certain places such as Gezirch Sporting Club, Today's issue of Al--Gumhuriyya mentions th t schools and universities will be opened on December 15, and that black out measures will be dropped on December 14

    Enabling effective project-team communication in the design phase of a BIM-enabled construction project

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    Productivity in the Architecture, Engineering, and Construction (AEC) industry is lacking. Projects in the industry have become larger and complex, leading to increasing amounts of information involved in the life cycle of a project. The low productivity of the construction industry over the previous decades has been linked to a ‘lack of communication and collaboration through information sharing’ (Boktor et al., 2014). In response, the industry has been searching for ways to systematize information sharing in a project. Building Information Modelling (BIM) has been widely embraced by the AEC industry as the answer to the difficulties in the industry. However, the implementation of BIM has not gone as smoothly as hoped. Extensive research has been done towards the barriers to BIM implementation and has resulted in the identification of three main categories of barriers: people, process, and technology. However, these results fail to acknowledge BIM is not the only method for communication in a project. The AEC industry is a knowledge-based industry that heavily relies on the experience of the people and their ability to collaborate with one another. This research considers a communication processes adept to the exchange of tacit knowledge, messy talk. In this research, the relationship between BIM and messy talk will be studied using activity theory. The main question reads: How can an organization enable effective project team context communication practices in BIM-enabled construction projects?The research is made up of three phases and was conducted using qualitative methods. The first phase consisted of creating a comprehensive understanding of the two concepts of this research, the use of BIM in BIM-enabled construction projects and messy talk.The second phase of the research was focused on testing this research proposition based on empirical data, collected through interviews and a case study. The empirical analysis was done using activity theory. Activity theory is a descriptive theory, well-suited to mapping so-called activity systems. The results from the activity systems analysis show that there are two scenarios in which messy talk occurs, characterized by the difference in the relationship of BIM and messy talk. The two scenarios, labelled as “problem identification” and “solution ideation”, can be linked to different aspects of the problem-solving cycle. Problem-solving requires both tacit and explicit knowledge. In comparing the two scenarios, the prompt of the messy talk as well as the intended outcome of the activity system differs. BIM plays a different role in either scenario, either as a prompt or a resolution. BIM can either be instrumental or the outcome of an interaction depending on the purpose of the messy talk. The output from either scenario of messy talk can act as an input to the other messy talk scenario but this is not bound to timeframe. Finally, the research is concluded in the third phase, where a strategy for enabling effective communication in a BIM-enabled construction is designed using the results from the empirical research. Based on the tensions and coping mechanisms identified in the activity systems, management interventions have been designed with the purpose of enabling messy talk, BIM, or both of these processes. 11 management interventions in the areas of team, instruments, external organizations, and leadership were identified to enable the communicative practices combining BIM and messy talk. The two scenarios can be placed in the larger design phase, thereby offering insights as to which management intervention should be employed when. These management interventions and as such the strategy can be tailored to an organization’s needs, abilities, and facilities. Further research is needed to create a more complete understanding of the relationship between BIM and messy talk. From this research, several areas of interest came up. These include further elements with an influence on the occurrence of messy talk, such as culture, division of labour or experience. Furthermore, similar research could be done to create an understanding of the role of messy talk in other phases of a construction project. Moreover, empirical data collection was limited, as such it could be worthwhile to do similar research with data collected from a broader array of project team interaction moments or from another party involved in the design phase or later stage of the project life cycle.Civil Engineering | Construction Management and Engineerin

    UA-R-GC-1914-01-01-1933-12-15_Page-034

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    1t5 Robert G. Andrus, "TAGORE A TEACHER", in the Arabic Journal of Modern Education, February 1933. Ismail Hussein Eff. "ARABIC READING, OLD & MODERN" in the Arabic Journal of Modern Education, February 1233. ditto "HOW ARABIC LITERATURE IS TAUGHT IN SECONDARY SCHOOLS", in The Arabic Journal of Modern Education, December 1232. ditto "A NEW METHOD OF CHARACTER TRAINING" in the Arabic Journal of Modern Education, April, 1933. Ismail Hussein Eff. has also written two books in Arabic on: POEMS by Izzet Sakr, with introduction and Literary Study. MUHYAR EL DAILAMY, A Critical Survey of his works. Dr. Zaky Mubarak. "EDUCATION IN SHAWKY' S POETRY . " in the Journal of Modern Education, December 1932. Also a weekly column in Al Balagh, Arabic daily newspaper. Amir Boktor iff. "WHAT'S NEW IN AMERICAN EDUCATION", in the Arabic Journal of Modern Education, December 1232. ditto "PSYCHOLOGY AND SEX", in the Arabic Journal of Modern Education, April 1933. Edmund Abdel Noor Eff. "WIRELESS IN EDUCATION" in The Arabic Journal of Modern Education, October 1932. Habib Eff. Iskander, author of the following text-books approved and selected by the Ministry of Education for use in Egyptian secondary schools:- Chemistry, for students in Fifty Year Government, scientific side. Phsycis, for students in Fifth 'ear Government, scientific side. Russell Galt,."THE CONFLICT OF FRENCH AND ENGLISH EDUCATIONAL PHILOSOPHIES IN EGYPT." In the Arabic Journal of Modern Education DeceAber 1232 and February 1933. Russell Galt, "PSYCHOLOGY OF FRENCH EDUCATION IN EGYPT". in The Arabic Journal of Modern Education, "pril, 1233. ditto "THE PROBL vI OF ISLALI" in Record of Chribtian work, 1 ovember 1932.. ditto "THE CONFLICT OF FRENCH AND ENGLISH EDUCATIONAL PHILOSOPHIES IN EGYP". A Monograph published by the American University at Cairo, •.arch 1933

    UA-R-GC-1914-01-01-1933-12-15_Page-034

    No full text
    1t5 Robert G. Andrus, "TAGORE A TEACHER", in the Arabic Journal of Modern Education, February 1933. Ismail Hussein Eff. "ARABIC READING, OLD & MODERN" in the Arabic Journal of Modern Education, February 1233. ditto "HOW ARABIC LITERATURE IS TAUGHT IN SECONDARY SCHOOLS", in The Arabic Journal of Modern Education, December 1232. ditto "A NEW METHOD OF CHARACTER TRAINING" in the Arabic Journal of Modern Education, April, 1933. Ismail Hussein Eff. has also written two books in Arabic on: POEMS by Izzet Sakr, with introduction and Literary Study. MUHYAR EL DAILAMY, A Critical Survey of his works. Dr. Zaky Mubarak. "EDUCATION IN SHAWKY' S POETRY . " in the Journal of Modern Education, December 1932. Also a weekly column in Al Balagh, Arabic daily newspaper. Amir Boktor iff. "WHAT'S NEW IN AMERICAN EDUCATION", in the Arabic Journal of Modern Education, December 1232. ditto "PSYCHOLOGY AND SEX", in the Arabic Journal of Modern Education, April 1933. Edmund Abdel Noor Eff. "WIRELESS IN EDUCATION" in The Arabic Journal of Modern Education, October 1932. Habib Eff. Iskander, author of the following text-books approved and selected by the Ministry of Education for use in Egyptian secondary schools:- Chemistry, for students in Fifty Year Government, scientific side. Phsycis, for students in Fifth 'ear Government, scientific side. Russell Galt,."THE CONFLICT OF FRENCH AND ENGLISH EDUCATIONAL PHILOSOPHIES IN EGYPT." In the Arabic Journal of Modern Education DeceAber 1232 and February 1933. Russell Galt, "PSYCHOLOGY OF FRENCH EDUCATION IN EGYPT". in The Arabic Journal of Modern Education, "pril, 1233. ditto "THE PROBL vI OF ISLALI" in Record of Chribtian work, 1 ovember 1932.. ditto "THE CONFLICT OF FRENCH AND ENGLISH EDUCATIONAL PHILOSOPHIES IN EGYP". A Monograph published by the American University at Cairo, •.arch 1933
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