179,165 research outputs found
Mitoplate S-1 analysis using R
No full textThis R script performs normalisation of data obtained with the MitoPlate S-1 commercialised by Biolog. In addition, it creates a scatterplot of initial rate values between conditions of interest. The script includes a first normalisation step using the "No substrate" well (A1) required for the rows A to H and a second normalisation step using the "L-Malic Acid 100 µM" (G1) only required for the rows G and H. Initial rate values are calculated as the slope of a linear regression fitted between 30 minutes and 2 hours
Simulation of a Fast Timing Micro-Pattern Gaseous Detector for TOF-PET and future accelerators
No full textSimulation is a powerful tool for designing new detectors and guide the construction of new prototypes. Advances in photolithography and micro-electronics led to the development of a new family of devices named Micro-Pattern Gas Detectors (MPGDs) [1], with main features: flexible geometry; high rate capability (> MHz/cm2); excellent spatial resolution ( 100µ m); good time resolution (5-10 ns); and reduced radiation length. A new detector layout, named Fast Timing MPGD (FTM), has been recently proposed [2] that would combine both the high spatial resolution and high rate capability of the MPGDs, while improving the time resolution with nearly two orders of magnitude to ~100ps. However charged particle timing with gaseous detector time resolution below 100 ps has been established with another detection scheme [3], this approach might not be able to sustain high particle rates. This contribution investigates the use of the FTM technology for an innovative TOF-PET imaging detector and emphases the importance of full detector simulation to guide the design of the detector geometry and performance
Analysis, design and retrofitting criteria for sequencing batch reactors in seismic area
No full textDevelopment of the FTM technology for TOF-PET
No full textGas detector research focused in particular on the radiation induced processes leading to discharge breakdown led, thanks to advances in photolithography and micro-electronics, to the development of a family of resistant devices named Micro-Pattern Gas Detectors (MPGDs) (Titov and Ropelewski 2013, [1]). The main features of the MPGDs are: a flexible geometry; a high rate capability (>MHz/cm2); an excellent spatial resolution
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Research and Enterprise for Sustainable Hemp Products and Buildings
No full textThis paper presents a research work aimed at promoting eco- sustainability and biocompatibility in the construction sector through a collabora- tion between the University and local entrepreneurs, according to the guidelines of the European Community. The study concerns the use of hemp sativa for the manufacturing of products and building elements and the use of these in the rede- velopment of existing buildings or in the construction of new buildings with low environmental weight. Having recognized the potential of hemp (especially as regards the provision of wellness, environmental protection and safety benefits) in the creation of an architecture that is friendly to man and the environment, the study focuses on the advantages of raw material use in building interventions (consider- ing the environmental criticality characterizing the contemporary landscape) and the environmental limits to be overcome with specific assessments for the same products. For the use of hemp in construction, the relationships between the mate- rial, the life of the buildings, the architectural quality, the images of the landscapes and the possible repercussions in terms of sustainable development. That is the way for defining beauty-oriented solutions through the dialogue between build- ings and ecosystems, for the quality of human life. The critical points of the life cycle phases of the examined hemp-based products are also highlighted, to guide effective evaluation processes, according to regenerative approaches inspired by nature. The work, referring to the context of the Abruzzo region (Italy), aims to provide a tangible contribution to the triggering of circular economies and building practices characterized by a strong balance between man, architecture and nature
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
The flexibility in social housing rehabilitation: the case of Preturo (Aq)
No full textThe present research is based on the study of three settlements situated in the neighbourhood of L’Aquila. L’Aquila extends over 466 squared km and its urban organization is nowadays constituted by the principal town and 68 hamlets; the ATER, that are the object of our research, are situated close to Monticchio, Preturo and Cansatessa; around them they have been constructed 19 post-earthquake CASE and MAP settlements which present the same problems of their hamlets: lack of essential services and isolation.
Our proposal of re-qualification is based on the city history and origin and on the outputs of present situation analysis, in order to re-establish a new identity of the city.
The main target is to define a development project able to give liveability back to the settlements considered, in accordance with a scattered territorial reality and with its evolving needs and problems. It is also necessary to reconstruct liveability of the settlements considering the historical origin of the city - L’Aquila foundation can be considered one of the most extraordinary urban event (Lavedan), due to the special link between the original castra and its part of city and thanks to the presence in every neighbourhood of a square, a church and a fountain - and the possibilities emerging from hidden realities.
The proposal is defined by a scalar process (from the urban to the building and component scale) and a circular process (from the urban re-qualification, with new centralities and standards, to the production of components able to fulfil with flexible building methods and to the regeneration of landscape and cultural and functional heritage thanks to the redefinition of territorial uses and resources).
The construction of a new city identity takes place combining the re-evaluation of historical heritage with the proposals of new centralities and aggregation points in order to heighten citizen life quality. We defined “accessibility ranges”, characterized by the presence of services, the environmental context, and the settlement framework, which can be connected in order to have a sustainable territorial functioning. Those ranges are the centralities to which can be connected infrastructures or network services, defining an adequate and efficient functional mix.
The strategies are related to the material and immaterial CONNEXION (mobility), that is the times and modes citizens can move all over the town and to ACCESSIBILITY and ENJOYABILITY (liveability), that is the possibility to take advantage not only of public and private services but also of green areas and aggregation and socialization points.
The final result is the transition from the presence of multiple centres to a polycentric structure, in which the different settlement levels, neighbourhood and town, can interact and dialogue each other.
The strategies for proposing a technical quality are basically focused on programs of energetic efficiency and adjustment of standards to user needs. The first one, thanks to adequate technical solutions, involves the analysis of urban microclimate, its implications in terms of outdoor comfort and the extent of its effects on indoor comfort.
The second one implies building reconstruction by means of re-qualification in reply to constantly mutable needs, largely conditioned by seismic risks. This program involves innovative building and component techniques able to project flexible housing in order to increase use possibilities of pre-existing houses.
The strategies to define a territorial re-generation and construction of a new landscape emerge from the necessity of a post-earthquake reconstruction; it was thought to promote local productive chains (industrial ecology) able to trigger locally social and economic development in accordance with sustainable criteria.
An analysis about local resources can define a possible future scenario: the primary and building sector necessarily integrated to transform local resources and waste into new resources, using new methods (urban metabolism) that consider the territorial image as functional and cultural landscape
Environmental and technological flexibility for new housing needs
No full text[EN] Over time, the economic and social conditions determined expansion and contraction processes of the domestic space (from the cave to the castle, from the castle to the studio flat) with important consequences on people s life quality. This evolution stimulated the development of cultural debates and design experiments on the theme of flexibility. In the contemporary scenario, flexibility has a big value because it represents an important design strategy to meet the needs of contemporary living in a sustainable dimension. For more than twenty years, the authors have been linked by a working relationship aimed at comparing theoretical scientific developments and design practice. This paper offers some reflections on the evolution of flexibility concept in residential construction by providing concrete examples through the reading of some projects. The variations of flexibility are debated with reference to the people s needs in the adaptive reuse of buildings. The writing faces the functional mix and the modifiability of interior spaces given by the design of flexible technological units (partitions, systems, furnishings) and mobile additions as well as the adaptability of the closures with respect to climatic and seasonal conditions. The theme of flexibility, too often oversized and not investigated in terms of feasibility, is presented in a possible and useful scale. Flexibility is also faced as a new way for showing the link between utility and beauty of the spaces.Radogna, D.; Kalhofer, G. (2022). Environmental and technological flexibility for new housing needs. VITRUVIO - International Journal of Architectural Technology and Sustainability. 7(1):30-45. https://doi.org/10.4995/vitruvioijats.2022.17461OJS304571Arbizzani, E., Baratta, A., Cangelli, E., Daglio, L., Ottone, F., Radogna, D. (2021), Architettura e Tecnologia per l’abitare. Upcycling degli edifici ERP di Tor Bella Monaca a Roma, Studi e progetti Serie, Maggioli, Santarcangelo di Romagna (Rn).Calcagnini L. (2018) Flessibilità. Una dimensione strategica per l’architettura, Cultura tecnologica e linguaggio architettonico Serie, Edizioni ETS, Pisa.Radogna, D. (2008) Kalhöfer & Korschildgen. Flessibilità ed esigenze d’uso. Soluzioni progettuali per un quadro prestazionale variabile, Sala Editori, Pescara.Radogna, D. (2012) La flessibilità per un Social Housing sostenibile: il caso di Preturo (AQ).TECHNE, Journal of Technology for Architecture and Environment, vol. 4, Social Housing.Radogna D. (2013) Flessibilita’ spaziale e tecnologica. In: Di Giulio R., Boeri A., Forlani M. C., Gaiani A., Manfron V., Pagani R. (ed.), Paesaggi periferici. Strategie di rigenerazione urbana, Quodlibet, MacerataRadogna D. (2020) Sistemi costruiti in via di sviluppo. In: Arbizzani E., Cangelli E., Daglio, L., Ginelli, E., Ottone, F., Radogna D. (ed.) Progettare in vivo la rigenerazione urbana, Studi e progetti Serie, pp. 39-42, Maggioli, Santarcangelo di Romagna (Rn)
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