101,090 research outputs found
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Seafloor environments of the eastern Timor Sea, Northern Australia: Sediment oxygen demand of seabed sediments.
No full textMaintenance and Update Frequency: asNeededStatement: Bulk sub-samples (6.5 ml) of surface sediment (0-2 cm) were incubated in BOD bottles for ~24 hrs in the dark at sea surface temperatures. Dissolved oxygen concentrations (and saturation values) were measured at the start and finish of each incubation. Results were expressed on a per g dwt basis utilising a separate sample to measure the water percentage. Analyses were corrected for blanks (filtered seawater).
The accuracies of the O2 measurements were +/- 1 mg/L. The accuracy of the scale used to measure wet/dry weights was better than 1%.The Timor Sea and its tropical marine environment support significant and growing economic activity including oil and gas exploration. To reduce uncertainty in decision making regarding the sustainable use and ongoing protection of these marine resources, environmental managers and resource users require sound scientific information on the composition and stability of seabed environments and their biological assemblages. Surveys SOL4934 and SOL5117 to the eastern Joseph Bonaparte Gulf were undertaken in August and September 2009 and July and August 2010 respectively, in collaboration with the Australian Institute of Marine Science, with research collaborations from the RAN Australian Hydrographic Office, the Geological Survey of Canada and the Museum and Art Gallery of the Northern Territory. The purpose of these surveys were to develop biophysical maps, and deliver data and information products pertaining to complex seabed environment of the Van Diemen Rise and identify potential geohazards and unique, sensitive environments that relate to offshore infrastructure. This dataset comprises sediment oxygen demand measurments made on the upper 2 cm of seabed sediments.<br/><br/><br/>Some relevant publications are listed below:<br/><br/>1. Heap, A.D., Przeslawski, R., Radke, L., Trafford, J., Battershill, C. and Shipboard Party. 2010. Seabed environments of the eastern Joseph Bonaparte Gulf, Northern Australia: SOL4934 Post Survey Report. Geoscience Australia Record 2010/09, pp.81.<br/>2. Anderson, T.J., Nichol, S., Radke, L., Heap, A.D., Battershill, C., Hughes, M., Siwabessy, P.J., Barrie, V., Alvarez de Glasby, B., Tran, M., Daniell, J. & Shipboard Party, 2011b. Seabed Environments of the Eastern Joseph Bonaparte Gulf, Northern Australia: GA0325/Sol5117 - Post-Survey Report. Geoscience Australia, Record 2011/08, 58pp.<br/>3. Radke, L.C., Li, J., Douglas, G., Przeslawski, R., Nichol, S, Siwabessy, J., Huang, Z., Trafford, J., Watson, T. and Whiteway, T. Characterising sediments of a tropical sediment-starved continental shelf using cluster analysis of physical and geochemical variables. Environmental Chemistry, in pres
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Measuring industry-science links through inventor-author relations: A profiling method
No full textIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
sj-docx-1-opp-10.1177_10781552231173863 - Supplemental material for A phase II trial of netupitant/palonosetron for prevention of chemotherapy-induced nausea/vomiting in patients receiving BEAM prior to hematopoietic cell transplantation
No full textSupplemental material, sj-docx-1-opp-10.1177_10781552231173863 for A phase II trial of netupitant/palonosetron for prevention of chemotherapy-induced nausea/vomiting in patients receiving BEAM prior to hematopoietic cell transplantation by Joseph S Bubalo, Jennifer L Radke, Kenneth G Bensch, Andy I Chen, Shikha Misra and Richard T Maziarz in Journal of Oncology Pharmacy Practice</p
Wave turbulence of a rotating array of quantized vortices in the T → 0 temperature limit
No full textThe dynamics of quantized vortices in the zero temperature limit is currently of great interest, particularly in the case of the Fermi superfluid He-B. Here we study wave turbulence, generated by the librating motion of a rotating cylindrical container filled with He-B, in the limit of vanishing viscous forces at temperatures . The polarization of the quantized vortices with respect to the axis of rotation is measured using non-invasive NMR techniques. We observe a decrease of the polarization when the librating motion is started, and a two-stage relaxation process when the modulation of the rotation velocity is stopped. The first relaxation process is associated with the dissipation of large-scale flow stored in inertial waves and the solid body rotation of the vortex array. From the decay of these energy reservoirs we determine the rate of energy dissipation of large-scale flow. The later second process is related to the relaxation of Kelvin waves on individual vortices. This process is monitored by the recovery of the polarization. The existence of a Kelvin wave cascade at the lowest temperatures is currently a central open question. We supply some evidence for the cascade
Outer Darwin Harbour Shallow Water Sediment Survey 2016: Total sediment metabolism, carbonate, organic isotope and organic and inorganic element data on seabed sediments.
No full textMaintenance and Update Frequency: notPlannedStatement: Bottom sediments were collected using either a box core or a Shipek grab. The surface sediments (~0-2 cm) within each grab were spooned into falcon vials and the pore waters were removed by centrifugation. Pore waters were removed within 20 minutes of collection, and salinity, temperature and pH measurements were taken. The pore waters were then filtered (0.45 µm) into 3 ml gas-tight vials (that were pre-charged with 0.025 HgCl2). The procedure was repeated on pore waters from a second bulk sample that was incubated for ~24 hrs at sea surface temperatures. The residual sediment samples were then frozen for transport to the laboratories at Geoscience Australia (GA) where they were: (1) subsampled for specific surface area analysis; and (2) freeze-dried and ground in a tungsten carbide mill. The dried residue was divided into fractions for: (i) major and trace element analysis; (ii) bulk carbonate analyses; and (ii) total organic carbon and total nitrogen concentrations and isotopic ratios (after de-carbonation).
Dissolved inorganic carbon (DIC) concentrations were determined on pore water samples using a DIC analyser and infrared-based CO2 detector (Geoscience Australia). CO2 production rates were calculated by concentration differences over the incubation period, after correction for CaCO3 fluxes. The average %RSD of the precisions and accuracies of the dissolved inorganic carbon measurements were 0.2. The accuracy of the wet/dry weight used in the calculations were better than 1%.
Bulk carbonate was determined on dried ground sediment using the carbonate bomb method. The average precision (%RSD +/- s.d.) for 11 samples run in duplicate was 1.6 +/- 1.7%.
Specific surface areas were determined using a 5-point Brunauer-Emmett-Teller (BET) adsorption isotherm on a Quantachrome NOVA 2200e analyser, with nitrogen used as the adsorbate. The samples were first cleaned of organic matter by slow heating for 12 hours to 350oC.
Major and trace elements were determined in GA laboratories using X-Ray fluorescence (XRF; Phillips PW204 4kW sequential spectrometer) and ICP-MS (AGILENT 7500ce). Two Certified Reference Materials (CRMs) called CH-1 (Marine Sediment; Institute of Rock and Mineral Analysis, Beijing) and WG-1 (Woodstock Basalt; Australian National University, Canberra) were run in triplicate to calculate accuracy. Ten to twelve samples were also analysed in duplicate to measure precision. De-carbonated powders were sent to Environmental Isotopes Pty Ltd (Sydney) for isotopic analysis by mass spectrometry. Samples were back-corrected to account for the carbonate removal, using carbonate concentrations derived from the bomb method (this dataset). Quality control information is presented with the accompanying datasets.A benthic sediment sampling survey (GA0356) to the nearshore areas of outer Darwin Harbour was undertaken in the period from 03 July to 14 September 2016. Partners involved in the survey included Geoscience Australia (GA), the Australian Institute of Marine Science (AIMS) and the Department of Environment and Natural Resources within the Northern Territory Government (NT DENR) (formerly the Department of Land and Resource Management (DLRM)). This survey forms part of a four year (2014-2018) science program aimed at improving knowledge about the marine environments in the regions around Darwin and Bynoe Harbour’s through the collection and collation of baseline data that will enable the creation of thematic habitat maps to underpin marine resource management decisions. This project is being led by the Northern Territory Government and is supported by the INPEX-led Ichthys LNG Project, in collaboration with - and co-investment from GA and AIMS. The program builds upon an NT Government project (2011-2011) which saw the collection of baseline data (multibeam echosounder data, sediment samples and video transects) from inner Darwin Harbour (Siwabessy et al. 2015). This dataset comprises Total sediment metabolism, %carbonate, organic isotope (C and N) and organic and inorganic element data from seabed sediments.<br/><br/>Radke, L., Smit, N., Li, J., Nicholas, T., Picard, K. 2017. Outer Darwin Harbour Shallow Water Sediment Survey 2016: GA0356 – Post-survey report. Record 2017/06. Geoscience Australia, Canberra. http://dx.doi.org/10.11636/Record.2017.006<br/><br/>This research was funded by the INPEX-led Ichthys LNG Project via the Northern Territory (NT) Government Department of Land Resource Management (DLRM) (now the Department of Environment and Natural Resources (DENR)), and co-investment from Geoscience Australia (GA) and Australian Institute of Marine Science (AIMS). We are grateful to the following agencies for providing boats and staff, and to the following personal for help with sample acquisition: NT DENR (Danny Low Choy and Rachel Groome), NT Fisheries (Wayne Baldwin, Quentin Allsop, Shane Penny, Chris Errily, Sean Fitzpatrick and Mark Grubert), NT Parks and Wildlife (Ray Chatto, Stewart Weorle, and Luke McLaren) and the Larrakia Rangers (Nelson Tinoco, Kyle Lewfat, Alan Mummery and Steven Dawson). Special thanks to the skippers Danny Low Choy, Wayne Baldwin, Stewart Weorle and Luke McLaren whose seamanship strongly guided the execution of this survey. AIMS generously allowed use of the aquarium and laboratory at the Arafura Timor Sea Research Facility, and Simon Harries and Kirsty McAllister helped with the setup. We would also like to acknowledge and thank GA colleagues including: Matt Carey, Ian Atkinson and Craig Wintle (Engineering and Applied Scientific Services) for the organisation of field supplies and the design of the new core incubation set-up. <br/><br/>This dataset is published with the permission of the CEO, Geoscience Australi
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