1,720,981 research outputs found
Development of machine learning schemes for segmentation, characterisation, and evolution prediction of white matter hyperintensities in structural brain MRI
White matter hyperintensities (WMH) are neuroradiological features seen in T2 Fluid-Attenuated Inversion Recovery (T2-FLAIR) brain magnetic resonance imaging (MRI) and have been commonly associated with stroke, ageing, dementia, and Alzheimer’s disease (AD) progression. As a marker of neuro-degenerative disease, WMH may change over time and follow the clinical condition of the patient. In contrast to the early longitudinal studies of WMH, recent studies have suggested that the progression of WMH may be a dynamic, non-linear process where different clusters of WMH may shrink, stay unchanged, or grow. In this thesis, these changes are referred to as the “evolution of WMH”.
The main objective of this thesis is to develop machine learning methods for prediction of WMH evolution in structural brain MRI from one-time (baseline) assessment. Predicting the evolution of WMH is challenging because the rate and direction of WMH evolution varies greatly across previous studies. Furthermore, the evolution of WMH is a non-deterministic problem because some clinical factors that possibly influence it are still not known. In this thesis, different learning schemes of deep learning algorithm and data modalities are proposed to produce the best estimation of WMH evolution. Furthermore, a scheme to simulate the non-deterministic nature of WMH evolution, named auxiliary input, was also proposed. In addition to the development of prediction model for WMH evolution, machine learning methods for segmentation of early WMH, characterisation of WMH, and simulation of WMH progression and regression are also developed as parts of this thesis
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Improving Segmentation of Objects with Varying Sizes in Biomedical Images using Instance-wise and Center-of-Instance Segmentation Loss Function
In this paper, we propose a novel two-component loss for biomedical image
segmentation tasks called the Instance-wise and Center-of-Instance (ICI) loss,
a loss function that addresses the instance imbalance problem commonly
encountered when using pixel-wise loss functions such as the Dice loss. The
Instance-wise component improves the detection of small instances or ``blobs"
in image datasets with both large and small instances. The Center-of-Instance
component improves the overall detection accuracy. We compared the ICI loss
with two existing losses, the Dice loss and the blob loss, in the task of
stroke lesion segmentation using the ATLAS R2.0 challenge dataset from MICCAI
2022. Compared to the other losses, the ICI loss provided a better balanced
segmentation, and significantly outperformed the Dice loss with an improvement
of and the blob loss by in terms of the Dice similarity
coefficient on both validation and test set, suggesting that the ICI loss is a
potential solution to the instance imbalance problem.Comment: conferenc
Few-shot medical image classification with simple shape and texture text descriptors using vision-language models
In this work, we investigate the usefulness of vision-language models (VLMs)
and large language models for binary few-shot classification of medical images.
We utilize the GPT-4 model to generate text descriptors that encapsulate the
shape and texture characteristics of objects in medical images. Subsequently,
these GPT-4 generated descriptors, alongside VLMs pre-trained on natural
images, are employed to classify chest X-rays and breast ultrasound images. Our
results indicate that few-shot classification of medical images using VLMs and
GPT-4 generated descriptors is a viable approach. However, accurate
classification requires to exclude certain descriptors from the calculations of
the classification scores. Moreover, we assess the ability of VLMs to evaluate
shape features in breast mass ultrasound images. We further investigate the
degree of variability among the sets of text descriptors produced by GPT-4. Our
work provides several important insights about the application of VLMs for
medical image analysis.Comment: 13 pages, 5 figure
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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