1,721,107 research outputs found
The bidirectional links between decision-making, perception and action
No full textIn different scientific disciplines, decision making is studied by examining how options are perceived or generated in isolated situations. In this chapter we explore the benefits of an interdisciplinary approach to understanding option perception within human behavior. As a consequence of the contributions from different disciplines, we present a framework that describes the bidirectional links between decision making, perception, and action. We will argue that, given their interdependency, the study of decision making profits greatly from a more integrated view of the situations it studies. The framework also illustrates how constraints may influence these bidirectional links. Finally, we use this framework to convey new ideas for experimental paradigms, data interpretation, and applications. © 2009 Elsevier B.V. All rights reserved
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A cognitive movement scientist's view on the link between thought and action. Insights from the Badische Zimmer metaphor
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Protein interactions with the platelet integrin alpha(IIb) regulatory motif
No full textIntegrins are transmembrane proteins regulating cellular shape, mobility and the cell cycle. A highly-conserved signature motif in the cytoplasmic tail of the integrin -subunit, KXGFFKR, plays a critical role in regulating integrin function. To date, six proteins have been identified that target this motif of the platelet-specific integrin IIb3. We employ peptide-affinity chromatography followed-up with LC-MS/MS analysis as well as protein chips to identify new potential regulators of integrin function in platelets and put them into their biological context using information from protein:protein interaction (PPI) databases. 44 platelet proteins bind with high affinity to an immobilized LAMWKVGFFKR-peptide. Of these, seven have been reported in the PPI literature as interactors with integrin -subunits. 68 recombinant human proteins expressed on the protein chip specifically bind with high affinity to biotin-tagged -integrin cytoplasmic peptides. Two of these proteins are also identified in the peptide-affinity experiments, one is also found in the PPI databases and a further one is present in the data to all three approaches. Finally, novel short linear interaction motifs are common to a number of proteins identified. <br/
The perception of natural and modulated movement sounds
No full textThe motor system is engaged when we perceive movement in the environment, even when we have no sensorimotor experience of that movement. It has been suggested that this ability relies on internal models that comprise specific exteroceptive representations, such as audition and vision. It has been shown that, for human movements, the quality of perception depends on the closeness between the perceived movement and the perceiver’s own capability of reproducing it. Thus, if we are able to reproduce a movement, we also have the interoceptive motor memories that enable us to run internal models and perceive the same movements more accurately when merely observed. In a behavioral study we investigated if participants would be able to distinguish between self-produced and other-produced movement sounds from a previously recorded hurdling performance. We also analyzed if participants’ discriminative ability would vary as a function of specific sound features, examining rhythmic step structure and amplitude range. The results reveal that participants were able to distinguish between their own and others’ movement sounds. However, changing either rhythmic step structure or amplitude range of the sounds did not influence this self– other discrimination. We suggest that identification of one’s own movement sounds is holistically achieved as an auditory gestalt
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