1,721,073 research outputs found
Cryopreserved Penile Tunica Albuginea for Allotransplantation: A Morphological and Ultrastructural Investigation
Full text linkIntroduction. Peyronie's disease, a connective tissue disorder of penile tunica albuginea (TA) associated with penile deformity, curvature, pain, and erectile dysfunction, is best managed surgically, but suitable graft biomaterials are not available. Aim. To establish whether cryopreservation affects human TA in view of its use in allotransplants. Methods. The effects on TA samples of the two most widely used tissue cryopreservation methods were investigated using an ad hoc panel of histochemical, immunohistochemical, and ultrastructural tests. Apoptotic cells were evaluated using the terminal deoxynucleotidyl transferase method of end labeling (TUNEL) assay. Main Outcome Measures. Assessment of tissue integrity and arrangement of collagen and elastic fibers in thawed TA. Results. Both cryofixation methods provided TA tissue suitable for use as graft material. Significant ultrastructural changes, namely, a greater diameter of collagen fibrils, were detected in sections preserved in liquid nitrogen; nonetheless, such increase never exceeded the normal range. The comprehensive panel of assays used proved suitable to characterize the thawed tissue. Conclusion. Human TA is suitable for cryopreservation; freezing at -80°C provides better results than preservation in liquid nitrogen. Loreto C, Orlandi A, Ferlosio A, Djinovic R, Basic D, Bettocchi C, Rutigliano M, Barbagli G, Vespasiani G, Caltabiano R, Musumeci G, and Sansalone S. Cryopreserved penile tunica albuginea for allotransplantation: A morphological and ultrastructural investigation. J Sex Med **;**:**-**
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
" L'investigazione scientifica e criminologica nel processo penale. Aspetti di Polizia scientifica, medico-legali e giuridici"
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Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Functional Bread Produced in a Circular Economy Perspective: The Use of Brewers’ Spent Grain
No full textBrewers’ spent grain (BSG) is the main by-product of the brewing industry, corresponding
to ~85% of its solid residues. The attention of food technologists towards BSG is due to its content
in nutraceutical compounds and its suitability to be dried, ground, and used for bakery products.
This work was aimed to investigate the use of BSG as a functional ingredient in bread-making. BSGs
were characterised for formulation (three mixtures of malted barley and unmalted durum (Da), soft
(Ri), or emmer (Em) wheats) and origin (two cereal cultivation places). The breads enriched with
two different percentages of each BSG flour and gluten were analysed to evaluate the effects of
replacements on their overall quality and functional characteristics. Principal Component Analysis
homogeneously grouped BSGs by type and origin and breads into three sets: the control bread, with
high values of crumb development, a specific volume, a minimum and maximum height, and
cohesiveness; Em breads, with high values of IDF, TPC, crispiness, porosity, fibrousness, and wheat
smell; and the group of Ri and Da breads, which have high values of overall smell intensity, toasty
smell, pore size, crust thickness, overall quality, a darker crumb colour, and intermediate TPC.
Based on these results, Em breads had the highest concentrations of nutraceuticals but the lowest
overall quality. Ri and Da breads were the best choice (intermediate phenolic and fibre contents and
overall quality comparable to that of control bread). Practical applications: the transformation of
breweries into biorefineries capable of turning BSG into high-value, low-perishable ingredients; the
extensive use of BSGs to increase the production of food commodities; and the study of food
formulations marketable with health claims
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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