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L'esame istopatologico della placenta per la comprensione delle alterazioni cardiotocografiche a termine di gravidanza.
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Clinical difficulties and forensic diagnosis: histopathological pitfalls of villus mesenchymal dysplasia in the third trimester causing foetal death.
No full textIn this article, the authors present a case of intrauterine foetal death (IUFD). The post-mortem histologic examination revealed placental mesenchymal dysplasia (PMD), a rare human placental disorder. Moreover, cases of PMD are often misdiagnosed as partial mole. The mother was a 26-year-old Italian, whose pregnancy, her first, had been uneventful until week 34+4 of gestation when IUFD suddenly occurred. The 2350 g male foetus showed no external abnormalities and the karyotype was 46, XY. The placenta weighed 450 g, the chorionic disk was round shaped, measuring 19.5-20.5 cm in diameter and had many enlarged villous structures. Histologically, the parenchyma showed abnormally enlarged and focally hydropic stem villi. Many of them were also surrounded by a fibrinoid material. Neither abnormal trophoblastic proliferation nor inclusion was observed in the examined sections. Causes and pathogenesis of PMD are still unclear and it is difficult to make a diagnosis solely on prenatal ultrasound during pregnancy. Generally, the correct diagnosis is reached only after the histological analysis of the placenta. However, obstetricians and gynaecologists should consider PMD also when a normal looking foetus is accompanied by a molar placenta (index factor for placentomegaly). The authors stress the importance of cooperation and information exchange among clinical and forensic pathologists, neonatologists, obstetricians and gynaecologists to avoid medical malpractice court proceedings in cases of IUFD
L’esame istopatologico della placenta:le basi patologiche per la comprensione delle alterazioni cardiotocografiche a termine e nel pretermine
No full textPerinatal deaths and lymphatic system involvement: a diagnostic flow-chart applying immunohistochemical methods
No full textA diagnostic flow chart is presented for use in case of perinatal death or still birth with non-immune hydrops fetalis, visceral effusions, or increased nuchal translucency. Immunohistochemical staining with CD-31, CD-34, D2-40, and smooth muscle actin is recommended
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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