1,720,969 research outputs found
Perceptions and motivations: An exploration of diet and fitness app use among college students
Get PDFRossi, Melissa. (2017). Perceptions and motivations: An exploration of diet and fitness app use among college students. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/189192
Realizzazione di un protocollo di coltura in vitro di tessuto endometriale equino e studio dell'espressione di geni correlati alla produzione di citochine infiammatorie dopo co-coltura dei campioni con due diverse dosi di cellule staminali mesenchimali.
Get PDFDespite the presence of an intense research in the field of the equine reproduction over recent decades, there has been no significant increase in the population's fertility. To date, few therapeutic protocols are available for the treatment of equine reproductive disorders because of the peculiarities of species but also for the ethical, clinical and economical reasons adressed to the in vivo tests. An easily obtainable sample for performing reliable in vitro tests is the endometrial biopsy; however, the lack of studies regarding the maintenance of the vitality for this sample is still an obstacle. For this purpose, the first aim of the present work has been the creation of a protocol for the culture of equine endometrial biopsies; moreover, we assessed the survival of two different kind of biopsy (incisional and excisional) by the estimation of mitochondrial activity, DNA quantity and the histology of the samples at 3 and 7 days of in vitro culture at 37°C and 5% CO2. Results show that incisional biopsies maintain an adequate level of vitality up to 3 days, representing a valid sample to be used for in vitro testing. In addition, the method allows the evaluation of innovative therapies such as mesenchymal stem cells (MSCs). MSCs have been shown to support tissue regeneration and to modulate inflammatory processes. For these reasons, MSCs could be used in equine endometritis and/or endometrosis, inflammatory-based pathologies that represent one of the major reproductive diseases for horse because of reducing the fertility of the animal and increasing costs for breeders. However, further insights are needed to improve the knowledge about their mechanism of action and their practical use. On the light of that, the second aim of this project has been the evaluation of the expression of genes related to the production of inflammatory cytokines after co-culture for 3 days of incisional endometrial biopsies with two different doses of adipose derived stem cells (ADSCs) (1x10^5 and 3 x 10^5 cells). The preliminary results allow us to hypothesize that the presence of ADSCs modifies the expression of genes involved in the production of cytokines with an immunomodulatory effect and possible activation of anti-bacterial and anti-fibrotic mechanisms that could be the starting point for the restoration of damaged endometrium. In addition, for some cytokines this immunomodulatory effect seems to be dose-dependent and deserves further studies
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
In vitro culture of equine endometrial biopsies as a model for the development of new uterine treatments
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Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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