1,722,888 research outputs found
"Walkie/Talkie 73+51 social sms al mondo, di Andrea Rossi Andrea"
No full textIl volume presenta il lavoro dell'artista contemporaneo Andrea Rossi Andrea, con particolare riferimento al suo impatto educativo
Libanio, ep. 1286 Förster e l’Ocypus di Acacio
Full text linkA letter sent by Libanius of Antioch (1286 F.) to his friend and correspondent Acacius proves that the addressee is the author of the short dramation on the gout, Ocypus, handed down within the corpus of Lucian of Samosata. This letter also allows to corroborate an emendation advanced by Enrico Magnelli at v. 74 in his recent edition of the text
Una riscrittura umanistica del Credo in esametri classici : il Symbolum Nicaenum di Paolo Pompilio
No full textThis article provides the editio princeps of a poetic paraphrase in hexameters of the Creed preserved in the manuscript Vatican lat. 2222 (XV century) and attributed to the Roman humanist Paolo Pompilio. After briefly presenting the author and his works, his Christian culture and the reasons which may have led him to compose a poetic paraphrase of the Symbol (the text is,indeed, part of a long-standing literary tradition), the article provides a critical edition of the text followed by a systematic, stylistic and literary commentary, which mainly aims at highlighting the poet’s debt towards classical, late-antique and medieval versification
Il carme In sanctam Christi resurrectionem di Giorgio di Pisidia: tradizione manoscritta ed edizione critica
No full textCritical edition with philological commentary of the poe
VALUTAZIONE CON METODICHE IMAGING DELLA DEPOSIZIONE ECTOPICA DEL TESSUTO ADIPOSO E SUE IMPLICAZIONI CLINICHE
Full text linkNelle ultime decadi si è assistito ad un aumento dell’interesse per la deposizione di grasso ectopico corporeo, come processo fisiopatologico implicato nelle alterazioni metaboliche dei soggetti obesi. In particolare la deposizione di grasso ectopico nel fegato sarebbe implicata nello sviluppo di insulino-resistenza e di progressivo danno epatico, prima metabolico e reversibile (NAFLD), poi infiammatorio e permanente (NASH). Nel pancreas si è osservato che l’infiltrazione lipidica è implicata nella disfunzione e nel danno alla massa β-cellulare.
Lo scopo di questo studio è stato quello di confrontare il grado di infiltrazione lipidica di fegato e pancreas tra soggetti di sesso maschile e femminile e valutare la relazione tra infiltrazione lipidica del fegato e del pancreas, e fenotipo di distribuzione regionale del tessuto adiposo, adipochine, marker infiammatori, introito calorico e lipidico quotidiano, prima e dopo calo ponderale. Tali soggetti sono quindi stati sottoposti ad intervento di 3-6 mesi di restrizione dietetica con riduzione calorica di 500 Kcal rispetto al dispendio energetico a riposo.
Sono stati inclusi nello studio alla valutazione basale 38 soggetti (18 uomini e 20 donne) con età media di 49.1 ± 13.0 anni e indice di massa corporea (BMI) di 34.9 ± 4.21 Kg/m2, non diabetici. Dei soggetti arruolati al basale 24 soggetti (13 uomini e 11 donne) hanno raggiunto calo ponderale >7% del peso iniziale e sono stati quindi sottoposti a valutazione dopo calo di peso.
In tutti i soggetti sono state valutate: variabili antropometriche (peso, altezza, BMI, circonferenza vita), composizione corporea (massa grassa e massa magra) con Dual Energy X-ray Absorptiometry, variabili metaboliche (glicemia, insulinemia, trigliceridi, indice HOMA), leptina, adiponectina, hsPCR, abitudini alimentari (apporto giornaliero di grassi con la dieta, introito calorico quotidiano); e tramite RMN quantità di tessuto adiposo viscerale (VAT), sottocutaneo (SCAT) e contenuto lipidico di fegato e pancreas.
Dai risultati è emerso che le donne hanno minor grado di infiltrazione lipidica del fegato e del pancreas rispetto agli uomini. Il tessuto adiposo viscerale è risultato il principale predittore di deposizione di grasso ectopico sia nel fegato che nel pancreas.
E’ stata inoltre osservata correlazione negativa tra adiponectina e deposizione di grasso ectopico sia nel fegato che nel pancreas.
Dopo calo ponderale medio dell’ 8.9%, si è assistito a significativa diminuzione di BMI, circonferenza vita e percentuale di massa grassa, così come delle principali variabili metaboliche, ALT, leptina e hs-PCR. Si è osservato significativo decremento di tessuto adiposo viscerale addominale e tessuto adiposo addominale totale ( p < 0.001) e del contenuto lipidico del fegato e del pancreas (p = 0.001). Dopo calo ponderale è stato osservato che la percentuale dei soggetti con steatosi epatica è diminuita dal 75% al 12.5% (p = 0.008). La riduzione del grasso viscerale osservata dopo calo di peso è risultata essere il migliore predittore del decremento del contenuto lipidico di fegato e pancreas. Il miglioramento dell’insulino-resistenza osservato dopo calo ponderale è risultato predetto in modo indipendente dalle variazioni del contenuto lipidico del fegato, della circonferenza vita e della PCR ad alta sensibilità.In the last few decades there has been increasing focus on body fat distribution rather than on the degree of obesity. More recently great interest has been also focused on the ectopic fat deposition (i.e. deposition of triglycerides at the level of liver, muscle and pancreas). Weight loss improves metabolic complications of obesity through visceral fat reduction. However little is known about the effect of weight loss on various ectopic fat compartments and about the possible contribution of ectopic fat reduction on metabolic alterations of obese subjects.
The purpose of this study was to compare liver and pancreas fat infiltration in men and women and determine the relationship between body fat distribution, adipocytokines, inflammatory markers, daily energy intake, dietary fat and lipid content of liver and pancreas, before and after weight loss.
The study population underwent a weight-loss program designed to achieve a loss of 10% of initial weight. The caloric restriction was 500 kcal below the resting energy expenditure, as evaluated by indirect calorimetry.
The present analyses were performed on 38 subjects (18 men and 20 women) with mean age 49.1 ± 13.0 years and mean body mass index (BMI) 34.9 ± 4.21 Kg/m. 24 subjects (13 men and 11 women) reached a >7% of initial weight and were therefore evaluated at follow-up.
Weight, height, body mass index (BMI), waist circumference, fat mass and fat mass percentage as evaluated with DXA, as well as glucose, insulin, HOMA, cholesterol, triglycerides, HDL-Ch, Hs-CRP, daily energy and fat intake, leptin and adiponectin were evaluated before and after weight loss. Magnetic resonance was used to evaluate visceral, subcutaneous adipose tissue as well as liver and pancreas lipid content using in-phase and out-of-phase MRI sequence.
Obese subjects had significantly higher weight, waist circumference, SCAT, Deep SCAT, VAT, liver and pancreatic lipid content than lean subjects. Obese women had significantly lower VAT, liver and pancreas lipid content regardless same BMI. In multiple regression analyses, the variance of liver lipid content explained by gender and VAT was 46%. When HOMA was added into a multiple regression a small increase in the proportion of variance explained was observed. A 59.2% of the variance of pancreas lipid content was explained by gender and VAT.
After a mean body weight decrease of 8.9 %, BMI, Waist circumference, total and FM %, as well as all metabolic variables, ALT, Hs-CRP and adipokines but adiponectin and HDL-Ch, significantly decreased (all p<0.01). Visceral, subcutaneous and total abdominal adipose tissue significantly decreased (p<0.001), as well as liver and pancreas lipid content (p<0.001 and p=0.001 respectively). After weight loss, percentage of subjects with steatosis decreased from 75% to 12.5% and none of the subjects had grade 2 or 3 of steatosis. Visceral adipose tissue decrease was the best predictor of the reduction in liver and pancreas lipid content observed with weight loss. The insulin resistance improvement observed after weight loss is mainly independently related with liver lipid content decrease, waist circumference and systemic inflammation reduction
Flexible Job Shop Scheduling with Sequence-dependent Setup and Transportation Times by Ant Colony with Reinforced Pheromone Relationships
Full text linkThis paper proposes a swarm intelligence approach based on a disjunctive graph model in order to schedule a manufacturing system with resource flexibility and separable setup times. Resource flexibility assigns each operation to one of the alternative resources (assigning sub-problem) and, consequently, arranges the operation in the right sequence of the assigned resource (sequencing sub-problem) in order to minimize the makespan. Resource flexibility is mandatory for rescheduling a manufacturing system after unforeseen events which modify resource availability. The proposed method considers parallel (related) machines and enforces in a single step both the assigning and sequencing sub-problems. A neighboring function on the disjunctive graph is enhanced by means of a reinforced relation-learning model of pheromone involving more effective machine-sequence constraints and a dynamic visibility function. It also considers the overlap between the jobs feeding and the machine (anticipatory) setup times. It involves separable sequence-independent and dependent setup phases. The algorithm performance is evaluated by modifying the well-known benchmark problems for JOB shop scheduling. Comparison with other systems and lower bounds of benchmark problems has been performed. Statistical tests highlight how the approach is very promising. The performance achieved when the system addresses the complete problem is quite close to that obtained in the case of the classical job-shop problem. This fact makes the system effective in coping with the exponential complexity especially for sequence dependent setup times
Un falso problema di testo in Gregorio Nazianzeno (nota critica a carm. 2.1.12, v. 426)
No full textThe paper proposes an exegesis and a solution to a difficult reading in a poem of Gregory of Nazianzus
Replication for "Unsmoothing Returns of Illiquid Funds"
No full textReplication code for "Unsmoothing Returns of Illiquid Funds
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