1,720,975 research outputs found

    Cystoid macular edema following cataract surgery.

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    CYSTOID MACULAR EDEMA FOLLOWING CATARACT SURGERY Alberto Rossetti and Daniele Doro Cystoic macular edema (CME) is the most common cause of unexpected visual loss following cataract surgery. CME occurring in aphakic eyes with intraretinal fluorescein angiographic cystoid spaces has been termed the Irving-Gas syndrome. After extracapsular extraction chronic CME with permanent visual loss is estimated to occur in approximately 1% of patients. The majority of cases occur between 4 and 12 week after cataract surgery. Predisposing factors are intraoperative complication ( e.g. vitreous loss or vitreous traction at the wound, severe iris trauma), diabetic retinopathy, and pre-existing epiretinal membrane. The authors describe the pathogenesis , the diagnosis, the symptoms , the prevention and the medical therapy of CME

    Complete versus Core Pars Plana Vitrectomy in a patient with TTR Tyr114Cys amyloidosis Alberto Rossetti MD*, Luigi Spedicato MD, Daniele Doro MD. Department of Neurosciences, Clinica Oculistica, University of Padua, Padua, Italy. * e-mail: [email protected]

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    Results One week after right diagnostic core 23-gauge PPV her visual acuity (V.A.) was 20/25 and 20/50 in the R.E. and L.E., respectively (Fig 4). After one month gross vitreous opacities limited her V.A. to 20/50 in the R.E. Seven months later 23-gauge complete PPV and IOL implantation was performed in the L.E., where preoperative V.A. was 20/200. One week after PPV her left V.A. reached 20/25, and amyloid deposits layered onto the macula and scattered in the vitreous cavity were found in both eyes (Fig.5). In the L.E V.A. decreased to 20/70 seven months later; IOP never exceeded 20mmHg. In the R.E. severe ocular hypertension was controlled with a fixed combination of dorzolamide and timolol , and eventually amyloid material in the anterior chamber was found (Fig.6); her right V.A. ended in counting fingers owing to glaucomatous optic atrophy (Fig.5)

    Intracorneal blood removal six weeks after canaplasty

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    In a 71-year-old patient with bilateral open-angle glaucoma, intracorneal blood was found after a canaloplasty procedure in the right eye. Six weeks after surgery on ultrasound biomicroscopy examination, liquified blood and blood clots could be observed nasally in the deep corneal stroma close to the Descemet's membrane. The intracorneal blood was washed out with balanced saline solution following deep corneal incision and lamellar dissection. Descemet's membrane was reattached with air injection into the anterior chamber. Two months later, visual acuity improved to 20/50, intraocular pressure was 16 mm Hg without medication and confocal microscopy showed deep stromal folds and limited endothelial cell loss. Viscoelastic entering the cornea at Schwalbe's line and reflux of blood from the collector channels to Schlemm's canal can account for corneal hematoma. Even six weeks after canaloplasty, successful blood removal could be fulfilled without rupturing the Descemet's membrane

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Long-term follow-up with optical coherence tomography and microperimetry in eyes with metamorphopsia after macula-off retinal detachment repair

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    PURPOSE: to report the long-term sequential morphological and functional results in eyes with metamorphopsia after retinal detachment (RD) repair. PATIENTS AND METHODS: in six eyes of six patients aged 58.7 ± 11.0 years with metamorphopsia after successful buckling surgery for macula-off RD, best-corrected visual acuity (BCVA), fundus biomicroscopy, Amsler grid test, time-domain optical coherence tomography (TD-OCT) and central 12° microperimetry (MP-1) were performed at months 1, 3, 6, 12, and 18. At 5 to 6 years after surgery all patients underwent also spectral domain (SD)-OCT. RESULTS: three eyes slowly recovered pre-RD BCVA. In the remaining three eyes-with good final BCVA-the interrupted junction line between photoreceptor cell inner and outer segments (IS/OS) was progressively less evident after RD surgery; and the external limiting membrane was preserved on SD-OCT examination. In all eyes post-operative metamorphopsia faded with time, but fully disappeared in 6 years only in two eyes without photoreceptor abnormalities. One of the two eyes with subretinal fluid up to 6 months and IS/OS disruption had central dense scotoma with relatively unstable fixation on MP-1 and persistent metamorphopsia. Macular sensitivity (MS) increased from 9.7 ± 7.1 at month 1 to 13.5 ± 5.6 dB at the final check, and was weakly (r=0.33) correlated with post-operative BCVA and OCT abnormalities. CONCLUSION: long-standing metamorphopsia can occur after successful macula-off RD repair even without detectable photoreceptor disruption on OCT. Post-operative BCVA recovery weakly correlates with increasing MS, and late restoration of the photoreceptor layer may be observed. PMID: 20948555 [PubMed - indexed for MEDLINE

    Bilateral optic neuropathy and intraretinal deposits after pars plana vitrectomy in amyloidosis

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    Abstract Pathological examination of material from a nonextensive pars plana vitrectomy (PPV) in the right eye provided a diagnosis of nonfamilial amyloidosis in a 68-year-old woman, who presented with bilateral glass wool-like vitreous opacities. Genetic testing revealed a Tyr114Cys mutation in the transthyretin gene. Six months after PPV, perimetry showed intense constriction with a temporal island and central scotoma in the right eye. An extensive PPV was performed in the left eye. Spectral domain optical coherence tomography evidenced bilateral epimacular amyloid deposits and unreported reflective spots within the inner retina. One year later, visual acuity had decreased to 20/400 in the left eye, with mild vitreous opacity, pale cupped optic disc and inferior altitudinal field defect. Bilateral diurnal intraocular pressure, transiently increased after PPV, never exceeded 16 mmHg with medication. Our patient presented optic nerve blood supply impairment, due to amyloidosis, which caused optic atrophy. Epiretinal and intraretinal deposit detection could aid in diagnosing patients with suspected amyloidosis
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