1,721,357 research outputs found
Design, characterization and validation of an innovative biosensor for illegal hypertrophy treatments detection in cattle breeding.
Full text linkThe work done during this PhD program, and presented in this thesis had the goal to design, develop and characterize a system for the detection of illegal anabolic treatments in cattle breeding, independently from the particular anabolic substance used. The system is aimed to allow for faster and cheaper controls with respect to standard techniques such as mass spectrometry, gas chromatography, and histological exams. Moreover, the system allows for on-the-field controls, drastically reducing the costs related to sample transportation, analysis, and trained personnel.
The main strength of this system is the independence of the anabolic treatments detection, from the particular substance employed, which makes this system optimal as screening method. Then, once identified the animals which has been treated, further analysis can be performed by standard techniques for the anabolic substance identification and quantification.
The independence from the anabolic substance is achieved by adopting a novel paradigm for anabolic treatments detection, based on the identification of a common hypertrophic effect induced by the anabolic substance on an in-vitro culture of mouse myogenic cells. The cells provided with the anabolic substances receptors, are engineered to react to the hypertrophic stimulus with the over-production of lactate, which is then released in the cell medium. Then, the lactate concentration in the medium is detected by an electrochemical enzyme-based biosensor, which allows for a rapid and precise quantification by a cheap and miniaturizable device. The quantification of lactate produced by the engineered cells allows the detection of on-going hypertrophic effect and thus of the presence of anabolic substances in the biological sample collected from the cattle
Le Turbe psichiche nella sclerosi multipla: un prodotto della inadeguatezza della risposta sociale e sanitaria ai bisogni dei malati
Full text linkQuesta relazione si propone di richiamare l'attenzione su alcuni aspetti medico-sociali di un gruppo fra i più deboli e indifesi all'interno della società: quello degli individui affetti da sclerosi multipla
The place of robotics in post-stroke rehabilitation
No full textReducing the impact of stroke on the independence of elderly patients during daily life is becoming a primary societal goal in developed countries owing to population aging and to the incidence of stroke in elderly people. Rehabilitation plays a fundamental role in reducing the residual motor deficits of stroke patients, both during hospitalization (acute/subacute phase, inpatient rehabilitation) and after discharge (chronic phase, ambulatory/home rehabilitation). Since 1995, when the first pioneering robotic system for rehabilitation was presented, the use of robotics in post-stroke rehabilitation has been investigated intensely, and positive, although not yet fully satisfactory, clinical results were obtained. This article presents the most recent developments in this young research field, outlining the state of the art and the prospective role of robotics in post-stroke rehabilitation
The infectious hypothesis of multiple sclerosis: increasing incidence of the disease in Sardinia, insular Italy
No full textManipulability of a planar wire driven haptic device
No full textThis paper presents a planar 4 wire driven 3 D.o.F. mechanism. For a planar haptic interface, this device could provide planar forces and moment feedback to the human operator. The particular end-effector geometric configuration overcomes manipulability problems arising from other recent planar wire haptic interfaces. Moreover, an explicit forward kinematic pose solution is obtained by introducing a modified wire configuration. Complete kinematic and manipulability analyses are presente
- …
